I predicted someone like Trump many years ago, in THE DEAD ZONE. So now I'm saying this--in the next 12-16 months, we're going to find out if the two machines for the removal of a man unable to fulfill his duties actually work. They are impeachment and the 25th amendment. He is deeply unwell .
I would be interesting to match some of the novel branches you are seeing to what we have.
Our work on 'hidden diversity' in unbinned contigs is now published in @natmicrobiol.nature.com :
www.nature.com/articles/s41...
See the linked threads for more details!
Yes, thanks for the wonderful study. What we've been seeing, and I've been saying. We are nowhere close to exploring the diversity still out there. We have currently characterizing lots of new phyla - hundreds of classes.
Dm me your email
Yeah, these are among the bigger open questions. We are just starting to see the lineages closest to euks. Examining more of these Heimdall, will reveal a lot. Those that we have imaged are revealing intracellular structures. for example, www.biorxiv.org/content/bior...
With @valdeanda.bsky.social @katyappler.bsky.social @emaguilarpine.bsky.social
Having a hard time keeping up with the fast-moving field of origin of eukaryotes/Asgards archaea? Our new perspective article can help, we review the status of research over the last decade and where it's going.
The archaeal roots of eukaryotic life
www.pnas.org/doi/10.1073/...
Yes.
Scientists are one step closer to understanding the origins of complex life on Earth after shedding new light on a mystery about our microbial ancestors. https://cnn.it/4srOEWd
Fun new paper out today - a collaboration led by @stephkoe.bsky.social and @ettema.bsky.social found lots of new Euk-like proteins in Asgard Archaea
www.nature.com/articles/s41...
Anyone have any new Asgards to read? If not, we have a new one coming on Monday haha.
Nice review! Actually next year will be the tenth anniversary of Asgards. Last year was the 10th of Loki.
🧵 1/10 New paper out in @natmicrobiol.nature.com from my postdoc at @mib-wur.bsky.social! 🎉
How eukaryote-like was the archaeal ancestor of eukaryotes? Sequence searches alone can't tell us — so we used protein structure prediction to look deeper. 🧬
www.nature.com/articles/s41...
Finally out in @natmicrobiol.nature.com: Prediction of eukaryotic cellular complexity in Asgard archaea using structural modelling. Great work by @stephkoe.bsky.social @kassipan.bsky.social @jvhooff.bsky.social
www.nature.com/articles/s41...
#NatMicroPicks
Aerobic archaeal-eukaryotic ancestor? 🦠🫁
The ancestor of eukaryotes may have combined hydrogen metabolism with aerobic respiration, shaping early cellular complexity.
#MicroSky
www.nature.com/articles/s41...
Nature research paper: Oxygen metabolism in descendants of the archaeal-eukaryotic ancestor
go.nature.com/4rSfRRw
By combining the ecological and evolutionary analyses, we present a Heimdallarchaeia-centric model for the origin of eukaryotes, based on our expanded genomic catalogue. #eukaryogenesis
9/12
Cytochrome c oxidase subunits in
Heimdallarchaeia show sequence homology and structural similarity to eukaryotic Complex IV.
Thus, providing a new perspective of the increasing complexity of the electron transport chain in these archaea.
8/12
Sequence and structural analysis of [NiFel-hydrogenases and flanking Complex I-like subunits identified 19 novel subgroups (doubling groups 3 and 4). Extensive structural analyses across Asgardarchaeota may further bridge the evolution of group 4 [NiFel-hydrogenases and Complex I.
7/12
Our findings show the current closest archaeal order to eukaryotes, Hodarchaeales, has been identified primarily in shallow coastal sediments and encode cytochrome c oxidase, heme biosynthesis, & responses to reactive oxygen species. Hodarchaeales also co-occur with Alphaproteobacteria.
6/12
