A cropped illustration of a dark blue Erlenmeyer flask filled with blue liquid and bubbles, on a coral-red background. Text reads: 4.27.26
Something new is taking shape, and we can’t wait to share it with you. Stay tuned!
The plasmids from Karapidaki et al. are on Addgene!
Grab them here:
www.addgene.org/browse/artic...
Bacteriophages are in a constant arms race with bacteria 🦠 The Phage ORFeome pooled library from the Aaron Whiteley lab contains phage proteins that activate antiphage defense systems — a tool to dissect the mechanisms of bacterial immunity. Aaron Whiteley
Thanks to depositors Jianjun Zhao and Andrei Alexandrov who have shared their plasmids with us - we're happy to help! 🥰
Thanks @michaelmarty.bsky.social for sharing! Find the plasmids here: www.addgene.org/browse/artic...
Plasmids evolved in the wild. 🧬 This lab created a modular, synthetic ORI to improve their use in the lab. Our new post is by the depositor of SynORI:
Find the plasmid here! Thank you for sharing with Addgene 🧬
www.addgene.org/240559/
Thank you for sharing your biosensors! 💚
SynORI plasmids from the Chappell Lab solve problems with plasmid copy number and plasmid incompatibility. If you want to modify your plasmid instead of your experiment, check out their post about the tool here:
New at Addgene!
A new modular CRISPRi plasmid kit for programmable and reversible control of gene expression in plants
https://twp.ai/4hpwgk
Ryan Lister
Check out this comprehensive resource from Botman et al. characterizing your favorite fluorescent proteins in yeast - and get the plasmids here!
https://twp.ai/4hpweF
Joachim Goedhart
Be CRISPRecise with this kit for minimizing off-target cleavage! This post explains the two step process for selecting the best Cas9 variant for YOUR target from the CRISPRecise kit.
GRACE plasmids for mapping #CRISPR activity patterns can be found at www.addgene.org/browse/artic...
Thanks for sharing!
please email us at help@addgene.org with more details. thanks!
Wish you knew how to pick a high-fidelity Cas9 to minimize off-target cleavage without having to test multiple variants in a genome-wide assay? This straightforward approach might be for you:
New to Plasmidsaurus? They're offering the Addgene community their first three sequences free with code ADDGENE. https://twp.ai/4iwdRq
Plasmidsaurus earned this partnership for good reason — they've sequenced over 5 million plasmids since 2021, delivering whole-plasmid results overnight with consensus accuracy that frequently reaches Q60. Reliable for even the most complex constructs.
Graphic with the headline "Meet Our New Sequencing Partner" above an illustrated T-rex examining a circular plasmid map through a magnifying glass, with the Plasmidsaurus logo below.
Every plasmid in Addgene's collection represents someone's hard work. When a researcher publishes, the community should be able to access that new tool, as a fully verified construct, without delay. Our partnership with Plasmidsaurus is how we scale that commitment as our collection grows.
Cystector plasmids now available!
We are excited for our new partnership with @plasmidsaurus.bsky.social and it shows!
We had way too much fun drawing these plasmid-loving dinos 🦖 🧬
Whatever your CNS gene transfer experiment calls for — Addgene has an AAV for that. With 1,000+ in-stock preparations and 30,000+ on-demand options, the collection keeps growing with new deposits every day.
Browse AAV preparations: https://twp.ai/4ixUFp
New antibody release! We've expanded our catalog of synaptic cleft antibodies with @ipiproteins.bsky.social's new antibodies targeting neurexins and neuroligins. Find these and more in our IPI Collection page:
Graphic with the headline "Keeping Pace with Discovery" above the Addgene and Plasmidsaurus logos.
Researchers around the world are constantly developing and sharing new tools, and getting those materials verified and into scientists' hands quickly is what drives us. That's why we've partnered with Plasmidsaurus to scale our sequencing as the collection grows. https://twp.ai/4ixUFf
Probing cancer-specific vulnerabilities? The Yeo Lab's RBP CRISPR KO In Vivo Library targets 206 RNA-binding proteins prioritized from screens in KRAS-, BRCA1-, and MYC-driven cancers. Compact size + dox-inducible Cas9 make it perfect for in vivo screens in tumor xenografts.
Find the plasmids that make these desmosomes glow here ✨👉
www.addgene.org/depositor-co...
Blugene holding a plasmid. A speech bubble contains an icon that says saved, with a red bookmark.
Your favorite plasmid, saved!
Use the new save feature on Addgene's site to bookmark items, organize them into custom lists, and share with others on your project 🔖
Wondering what's the difference between Halorhodopsin and Channelrhodopsin? Curious how a plant photosensor domain could power your next gene editing experiment? Check out our Optogenetics Guide to learn about these tools and more to light up your lab! 🧠💡🔬
New at Addgene!
Do you study non-model bacteria? Cultivarium has you covered with their JEROBA (Jumping Element libRaries with Broad hOst rAnge) Toolkit. Use this kit to screen different transposon configurations and find the optimal constructs for your unique bacteria 🦠
https://twp.ai/4ixKCP
Never lose track of a plasmid again!
New on Addgene: Saved Lists! Save items as you browse, organize into custom lists, and share with collaborators when you're ready.
https://twp.ai/4ixKBR
