Great effort by @yuemauom.bsky.social and collaboration with @ackermannkatrin.bsky.social @belab.bsky.social group. Research performed in @mcf-uom.bsky.social @uommib.bsky.social @fbmh-uom.bsky.social
In our study in @natcomms.nature.com we used #EPR #DEER #PELDOR spectroscopy with single subunit heterologous spin labelling and monitored the entire cap conformational ensemble of the human mechanosensitive TRAAK channel and showed it adopts two states in membranes.
www.nature.com/articles/s41...
15 PhD positions fully funded! Apply until 6 January 2026
www.findaphd.com/phds/?Keywor... #DoctoralTraining #ResearchCareers #LifeSciences #BiomedicalResearch #ResearchOpportunities#PhDPositions#MSCA#EU#Antimicrobialresistance#Microbiology#Structuralbiology
We have a new academic post opening for a Lecture/Senior-Lecturer in Structural Biology @mcf-uom.bsky.social @fbmh-uom.bsky.social @manchester.ac.uk The University of Manchester is ranked among the top Universities worldwide. QS world rankings: 34th (2025)
www.jobs.manchester.ac.uk/Job/JobDetai...
Congratulations to Maria Chiara Pagliero and Anand Anilkumar who were the winners of the IEPRS Poster Prizes awarded from the International EPR Society at the 10th EFEPR Summer School at The University of Manchester
@officialuom.bsky.social
Funded by @ukri.org
@mcf-uom.bsky.social @uommib.bsky.social @fbmh-uom.bsky.social
In our study @elife.bsky.social we uncover the mechanism of mPPase inhibition. Over 20x structures to date are in a symmetric form. We use EPR(PELDOR/DEER) and reveal asymmetric binding at the active site while maintaining symmetric conformation at periplasmic site
elifesciences.org/reviewed-pre...
@Bruker's ELEXSYS E580Q Spectrometer has found its new home at the University of Manchester (@OfficialUoM)!
Watch as an empty lab is turned into a cutting-edge #EPR lab & hear from Prof. Christos Pliotas, who leads the research group driving innovation.
👉 youtu.be/Hz4fCqh8PeY [youtu.be]
webinar poster
Wednesday, April 23, 9 am EDT / 3 pm CEST, IVEM webinar, Christos Pliotas @pliotasgroup.bsky.social University of Manchester, Accessing uncharted membrane protein ensembles by structural biological EPR spectroscopy www.eprseminars.org #NMRchat #NMR #EPR #ESR 🧲 🧪
2025 IES John Weil Young Investigator Award: Nino Wili his outstanding contributions to theory and instrumentation in the field of EPR spectroscopy.
2025 IES Medal in Biology/Medicine: awarded to Olav Schiemann for his seminal contributions advancing the field of EPR in Biology via his pioneering efforts to resolve structural aspects of spin labelled nucleic acids and proteins.
Early-career fellowships at the University of Manchester!
To celebrate 200 years of The University of Manchester, the Faculty of Biology Medicine and Health offers a 3-year Postdoctoral Fellowship to support exceptional early-career researchers:
www.bmh.manchester.ac.uk/research/sup...
Apply now for the 10th EFEPR Summer School in Manchester, UK, 31st Aug – 6th Sept 2025.
Attendees will receive training in advanced EPR theory & methods including hands on practical sessions. chemistry.manchester.ac.uk/epr/connect/... Expression of interest deadline: 21st Mar 2025
& Collab with @stemuench.bsky.social @drjonlippiat.bsky.social @astbury-bsl.bsky.social @astburycentre.bsky.social @mcf-uom.bsky.social @uommib.bsky.social @mariangeladiony.bsky.social
In our recent article we show the YbiO mechanosensitive channel can achieve pore openings of 3nS under membrane tension equalling the largest known gated-pore MscL and we also solve a cryo- EM structure of a YbiO in a sub-open state. Great effort by @lane-b.bsky.social www.cell.com/structure/fu...
We reviewed recent pulsed EPR Spectroscopy (PELDOR/DEER/PDS) applications on integral membrane proteins, enabled through Spin Labelling. Great to see the field moving forward!
www.sciencedirect.com/science/arti...
New starter pack on EPR - ESR spectroscopy: go.bsky.app/KJZ4P8X
