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Posts by Hannah R. Abrams

When you read about applications of "AI" in medicine, a good Q to ask is "what is the billing code for that 'service'?"

In the case of "screening" for IPV, no indication is required (unlike "assessments").

To document physical abuse, you can use ICD-10 code T74.1. Relevant source:

1 week ago 16 9 1 1
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Toxicity of Capecitabine and Oxaliplatin as Adjuvant Therapy for Stage III Colorectal Cancer Patients With Diverting Stoma | JCO Oncology Practice PURPOSEStandard adjuvant treatment for stage III colorectal cancer (CRC) combines intravenous oxaliplatin with a fluoropyrimidine, either with intravenous 5-fluorouracil with folinic acid…

CapeOx vs FOLFOX for adjuvant treatment in people w stage III colorectal #cancer & a diverting stoma:

- ⬆️ hospitalizations, mostly GI effects (35% vs 18%)
- ⬆️ rate of dose-reducing oxali (92% vs 40%)
- ⬆️ diarrhea, mucositis, HFS

😨 mFOLFOX6 much better for QOL. #CRCSM ascopubs.org/doi/10.1200/...

2 weeks ago 1 0 0 0

This is especially important now that we're dealing with Medicaid paperwork requirements because it's so difficult to document gig work (which is disproportionately performed by Black and Hispanic workers, who are in turn more vulnerable to falling through the cracks and losing health coverage).

3 weeks ago 26 11 1 0

Unfortunately every complaint I have seen about the Pitt from health care-associated people makes it sound more accurate to real life…

3 weeks ago 1 0 0 0

NGL, I kinda did see "rural hospital closures" becoming a hot-button issue. The framing is already so polarized- crowding out similar focus on urban hospital closures (which also lead to bystander effects, e.g., crowding at surviving hospitals & worsen access for urban-dwelling communities of color)

3 weeks ago 5 1 2 0

Someone with a platform and a gift for policy/research translation needs to get ahead of this.

3 weeks ago 11 4 0 0
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The Power of “I Don't Know”

“Will it work?”
 
“I don't know…
 
But we have a plan.”
 
“I don't know” does not mean “I have nothing to offer.” It means “I will not pretend to know when I don't, and I will stand with you in the uncertainty.”
 
Loved this @ascocancer.bsky.social #ArtofOncology by #radonc Dr Sondos Zayed

3 weeks ago 10 1 2 0

Something that shouldn’t be lost is @drugmonkey.bsky.social highlighting these are training awards. Overall a devastating blow to the groups targeted.

Not only were grants terminated (which shrinks the pool of people who can stay in science), a huge drop off in new awards also shrinks the pipeline.

4 weeks ago 13 5 1 0
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a bald man is holding a hairless cat and the caption says it 's a homonym ALT: a bald man is holding a hairless cat and the caption says it 's a homonym

Great learning on data science algorithms by Tina Hernandez-Boussard: when a predictive algorithm works @stanford-cancer.bsky.social but fails when used at @massgeneralbrigham.bsky.social because one hospital uses "Depends" to refer to an adult diaper and the other uses "depends" only as a verb...

3 weeks ago 1 1 0 0
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"You're getting mixed signals as to what you represent, and the kind of work that you should be doing" said Jahn Jaramillo, a Ph.D. candidate at the University of Miami who recently published an analysis of the F31 awards that were terminated after his own grant was terminated. His grant, which had received a perfect peer review score, was on HIV in the Latino immigrant community. In some ways, the grant was squarely within the priorities of the Trump administration, which announced a plan in 2019 to end the HIV epidemic. Miami, where Jaramillo is based, is an area of high priority for that initiative. The work also felt particularly meaningful to Jaramillo, as a way to help communities he is part of.

"You're getting mixed signals as to what you represent, and the kind of work that you should be doing" said Jahn Jaramillo, a Ph.D. candidate at the University of Miami who recently published an analysis of the F31 awards that were terminated after his own grant was terminated. His grant, which had received a perfect peer review score, was on HIV in the Latino immigrant community. In some ways, the grant was squarely within the priorities of the Trump administration, which announced a plan in 2019 to end the HIV epidemic. Miami, where Jaramillo is based, is an area of high priority for that initiative. The work also felt particularly meaningful to Jaramillo, as a way to help communities he is part of.

But now, it feels as if his identities are being weaponized. "I was able to do that kind of community outreach work. You speak the language, you're very close to the community, so you're able to get research participants that perhaps had never engaged in research before," Jaramillo said.
But when his grant was terminated halfway through the project, he added, "you're disappointing them, you're confusing them.
That has long-term impacts with regards to them trusting research."

But now, it feels as if his identities are being weaponized. "I was able to do that kind of community outreach work. You speak the language, you're very close to the community, so you're able to get research participants that perhaps had never engaged in research before," Jaramillo said. But when his grant was terminated halfway through the project, he added, "you're disappointing them, you're confusing them. That has long-term impacts with regards to them trusting research."

Infuriating story

Future Dr. Jaramillo got a perfect score on his proposal. “Diversity” awards are scored w/ the same criteria as others.

The new admin claims they are exchanging “DEI” for “merit”. In practice they are shutting down research mid-project even if they have the highest “merit”

4 weeks ago 30 12 3 2
Title page and abstract:
Cost-Effectiveness of Maintaining Higher Stem-Cell Collection Thresholds in the Chimeric Antigen Receptor T-Cell Era for Multiple Myeloma
Ehsan Malek, MD 1 ; Brian Betts, MD 1 ; Megan Herr, PhD 1 ; Marco Davila, MD 1 ; Shernan Holtan, MD 1 ; James J. Driscoll, MD, PhD 2,3 ; and Han Yu, PhD 1

Title page and abstract: Cost-Effectiveness of Maintaining Higher Stem-Cell Collection Thresholds in the Chimeric Antigen Receptor T-Cell Era for Multiple Myeloma Ehsan Malek, MD 1 ; Brian Betts, MD 1 ; Megan Herr, PhD 1 ; Marco Davila, MD 1 ; Shernan Holtan, MD 1 ; James J. Driscoll, MD, PhD 2,3 ; and Han Yu, PhD 1

FIG 3. Cost breakdown by strategy. Stacked bar chart of per-patient costs for the no-boost and boost
strategies. In the no-boost arm, all costs are attributable to hospitalization for infection. In the boost
arm, upfront reserve collection accounts for the majority of costs, while infection-related costs are
markedly lower. Total costs for each strategy represent the sum of upfront collection/storage fees
and longitudinal infection-related hospitalization costs. USD, US dollars.

Figure demonstrates cost per patient >$20,000 in boost group, under $5000 in no boost group. Majority of costs attributable to cost of stem cell collection up-front.

FIG 3. Cost breakdown by strategy. Stacked bar chart of per-patient costs for the no-boost and boost strategies. In the no-boost arm, all costs are attributable to hospitalization for infection. In the boost arm, upfront reserve collection accounts for the majority of costs, while infection-related costs are markedly lower. Total costs for each strategy represent the sum of upfront collection/storage fees and longitudinal infection-related hospitalization costs. USD, US dollars. Figure demonstrates cost per patient >$20,000 in boost group, under $5000 in no boost group. Majority of costs attributable to cost of stem cell collection up-front.

Should we be reserving stem cells for every patient with #myeloma treated with BCMA CAR T?

Reduces severe infections by over half, but >4x cost. Need risk-stratification (or IVIG) to make sustainable.

Cost effectiveness modeling in #JCOCCI :
ascopubs.org/doi/10.1200/...
@ziadbakouny.bsky.social

4 weeks ago 3 1 1 0
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This is cool: fullerenes, these neat carbon structures discovered in 1985 @ Rice University, significantly reduced incidence of radiation dermatitis in people with head & neck cancer getting radiation.

Tx groups not perfectly matched, but encouraging study.
ascopubs.org/doi/10.1200/...

4 weeks ago 1 0 0 0

This would be terrible.

99% of Medicare Advantage enrollees have prior authorization, a departure from how traditional Medicare has historically operated (though Oz is changing that), which causes delays and denials. What’s more, networks are often very limited, further reducing access to care.

1 month ago 29 17 1 0
Table 3. Practice Implications for Oncology Providers in Low-Broadband Settings
Practice Domain	Key Implication
Proactive Offering	Proactively offer VTVs even in low-broadband regions; patients may adopt VTV when given the option
Modality Matching	Reserve in-person care for essential physical examinations, labs, transfusions, or imaging, while offering VTV for follow-ups, counseling, and routine check-ins
Situational Flexibility	Frame VTV as a safe and practical alternative, especially, during adverse weather, long travel distances, or out-of-state circumstances
Digital Readiness	Build digital comfort through low-stakes trial runs, patient portal tutorials, or staff-led technology coaching to reduce first-visit barriers
Relational Care	Validate patients' preference for face-to-face care while emphasizing strategies to maintain connection, attention, and trust during VTV
Future Planning	Normalize VTV as a scalable option that patients may increasingly rely on with aging, mobility limitations, or worsening weather conditions

Table 3. Practice Implications for Oncology Providers in Low-Broadband Settings Practice Domain Key Implication Proactive Offering Proactively offer VTVs even in low-broadband regions; patients may adopt VTV when given the option Modality Matching Reserve in-person care for essential physical examinations, labs, transfusions, or imaging, while offering VTV for follow-ups, counseling, and routine check-ins Situational Flexibility Frame VTV as a safe and practical alternative, especially, during adverse weather, long travel distances, or out-of-state circumstances Digital Readiness Build digital comfort through low-stakes trial runs, patient portal tutorials, or staff-led technology coaching to reduce first-visit barriers Relational Care Validate patients' preference for face-to-face care while emphasizing strategies to maintain connection, attention, and trust during VTV Future Planning Normalize VTV as a scalable option that patients may increasingly rely on with aging, mobility limitations, or worsening weather conditions

2. How do people living in low broadband access areas feel about Telehealth visits? Surprisingly open - and asking for more proactive outreach.

ascopubs.org/doi/10.1200/...

1 month ago 0 0 0 0
TABLE 2. Participant-Reported Measures: Prognostic Perceptions and
Hope at the Time of Phase I Clinical Trial Enrollment
27.4% report goal of cancer treatment is to cure cancer, 40% describe themselves as not terminally ill, and 37.8% report never or rarely discussing prognosis with oncologist.

TABLE 2. Participant-Reported Measures: Prognostic Perceptions and Hope at the Time of Phase I Clinical Trial Enrollment 27.4% report goal of cancer treatment is to cure cancer, 40% describe themselves as not terminally ill, and 37.8% report never or rarely discussing prognosis with oncologist.

Two important patient-perspective studies JCO OP @jco-asco.bsky.social this week:
1. What do people w/ advanced cancer participating in early-phase clinical trials (ie, Phase 1) understand about their prognosis?

27% believe cancer is curable
38% report never discussing prognosis w/ oncologist.

1 month ago 1 0 1 0
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Interplay Between Psychological Burden, Economic Stress, and Quality of Life in Chronic Myeloid Leukemia Care: An Integrated Analysis | JCO Oncology Practice PURPOSEAs survival rates among patients with chronic myeloid leukemia (CML) have improved significantly, treatment goals have expanded from disease control to optimizing long-term quality of life…

Shift in #CML care in era of 📈 treatment options: many patients still have poor quality of life when experiencing multiple side effects of their TKIs despite excellent disease control. Justifies need for tx-free remissions, wider STAMPi access @jco-asco.bsky.social

ascopubs.org/doi/10.1200/...

1 month ago 1 0 0 0
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Broken incentives: when a $3K/year cancer treatment may cost patients more than a $200K/year one. 💸

Why isn't structured exercise getting the uptake it should? Follow up in @jco-asco.bsky.social on economics of #ChallengeTrial @csoncol.bsky.social

ascopubs.org/doi/pdf/10.1...

1 month ago 2 1 0 0
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a woman says that seems silly with a netflix logo behind her ALT: a woman says that seems silly with a netflix logo behind her

Cancer screenings are supposed to be provided at no cost to the patient, but way too often, patients receive medical bills for ancillary services. Those are medical services delivered solely because of screening but not classified as screening themselves (e.g., anesthesia for colonoscopy).

1 month ago 2 1 1 0
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Ancillary Services to Screening Mammography and Colonoscopy Burdened by Patient Cost-Sharing - Journal of General Internal Medicine Journal of General Internal Medicine -

🚨🚨🚨 NEW PAPER ALERT 🚨🚨🚨
In this @journalgim.bsky.social brief report, @alexhoagland.bsky.social, our clinical co-authors, and I lay out ancillary services to screening mammography and colonoscopy, for which patients receive medical bills.
link.springer.com/article/10.1...

cc: @acscan.bsky.social

1 month ago 5 4 1 0

In terms of healthcare systems, accessibility of healthcare, area-level concentrated advantage has implications for the profitability of healthcare provision to residents in these areas. Health systems- even non-profit- are incentivized to provide care where residents have greater "ability to pay."

1 month ago 3 2 1 0

Yes, poverty is frequently racialized AND spatialized. Occupational segregation, residential segregation, etc concentrate disadvantage (e.g., lower educational attainment, lower entry into higher paying professions, lower likelihood of having employer-sponsored health insurance...).

1 month ago 3 1 1 0
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Same-Day Multidisciplinary Clinics for Patients With Newly Diagnosed Adult Solid Tumor Cancer: A Systematic Review | JCO Oncology Practice PURPOSESame-day, colocated multidisciplinary clinics (MDCs) aim to expedite complex cancer care, yet their added value over sequential referral remains uncertain. We systematically reviewed comparativ...

Are you an oncologist? Do you have strong opinions about pros & cons of same-day multi-D clinics for people newly diagnosed w/ solid tumors?

I suspect there's about 95-99% overlap between "yes" answers...

A little data to inform those opinions in @jco-asco.bsky.social:
ascopubs.org/doi/10.1200/...

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Clinical Trial Participation Among Patients With Pancreatic Cancer: A Pancreatic Cancer Action Network Patient Survey | JCO Oncology Advances PURPOSEDespite ongoing efforts, outcomes among patients with pancreatic ductal adenocarcinoma (PDAC) remain poor. Clinical trials are indispensable for therapeutic innovation, yet accrual among…

Surprising finding in JCO OA: Pancreatic cancer patients at a community site were MORE likely to be offered & participate in a clinical trial than those at an academic site. Caveat of selection bias, but credit to these clinics! @pancan.bsky.social
@jco-asco.bsky.social
ascopubs.org/doi/full/10....

1 month ago 0 0 0 0
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Perhaps It Was Too Good to Be True: Oncologists Struggle to Report G2211 | JCO Oncology Practice

New article in @jco-asco.bsky.social gets into the details, but why do you think people are not yet using it?

ascopubs.org/doi/10.1200/...

1 month ago 2 0 0 0
Fig 2. Medicare projected versus actual utilization of G2211. All physicians were anticipated to report 83.7 million uses of the code but only reported 24.7. Hematology/oncology physicians expected to report 3.2 million but only reported 1.6 million.

Fig 2. Medicare projected versus actual utilization of G2211. All physicians were anticipated to report 83.7 million uses of the code but only reported 24.7. Hematology/oncology physicians expected to report 3.2 million but only reported 1.6 million.

Why aren't docs using code G2211?

G2211 is a new billing code for longitudinal care of complex conditions, but overall MDs are using it ~25% the rate anticipated. Other pay was adjusted to make room, so this is in net a loss to MDs providing continuity of care - the thing we want.

1 month ago 2 0 1 0
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Trump Required Hospitals To Post Their Prices for Patients. Mostly It’s the Industry Using the Data. - KFF Health News Politicians have pushed for price transparency in health care. But instead of patients shopping for services, it’s mostly health systems and insurers that are using the information, as fodder for nego...

Regardless of the partisan affiliation of the sitting president, "price transparency" was always going to be most useful for firms with actual market power versus patient-consumers #InformationAssymetry

1 month ago 28 6 2 0
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Adding to my HPM 756 slides. The point about homicide is especially salient.

2 months ago 54 23 3 1
Fig 1. Reference characteristics to the article by Ross et al by year of publication. Stacked area chart depicting the distribution of citation characteristics referencing the article by Ross et al, categorized by publication year (2010-2025). Each color represents a distinct citation characteristic: Affirmative, contrastive, assumptive, conceptual, methodologic, perfunctory, and negative. Vertical dashed lines mark two key regulatory events: the 2011 cisplatin label update and the 2015 label revision.

Fig 1. Reference characteristics to the article by Ross et al by year of publication. Stacked area chart depicting the distribution of citation characteristics referencing the article by Ross et al, categorized by publication year (2010-2025). Each color represents a distinct citation characteristic: Affirmative, contrastive, assumptive, conceptual, methodologic, perfunctory, and negative. Vertical dashed lines mark two key regulatory events: the 2011 cisplatin label update and the 2015 label revision.

It's taken over 10 years for an erroneous reference to (almost) make it out of the citation chain.

Less about the reference itself (incorrect claim re: cisplatin ototoxicity) and more about our science.

Case report here @jco-asco.bsky.social:
ascopubs.org/doi/10.1200/...

2 months ago 1 0 0 0
Low-Intensity Vibration to Reduce Symptoms and Improve Physical Functioning in Cancer Survivors With Chemotherapy-Induced Peripheral Neuropathy: A Pilot Randomized Trial | JCO Oncology Practice PURPOSEChemotherapy-induced peripheral neuropathy (CIPN) can have deleterious effects on mobility and quality of life in people with cancer. Vibration therapy shows promise as a CIPN intervention but…

Increasing options for chemotherapy-induced peripheral neuropathy: in a 38-patient RCT, low intensity vibration was safe, well adhered-to, and improved neuropathy + function:

ascopubs.org/doi/10.1200/... #oncsky @jco-asco.bsky.social @ohsuknight.bsky.social

2 months ago 7 3 0 0