Top: A picture of the aye-aye named Elphaba. Image credit: David Haring, Duke Lemur Center. Bottom: Pedigree structure of the aye-ayes used in this study. The 18 individuals sequenced in this study are shown: males as squares and females as circles. Two individuals (IDs 100937 and 100935) appear multiple places in the pedigree, each time connected by a dashed line. Elphaba is at the bottom right.
Aye-ayes are clearly unusual, but @glom.bsky.social @3rdreviewer.bsky.social &co show that they also have an unusual pattern of #MutationBias; older females transmit more mutations than males. This is a first for mammals, raising questions about other #lemurs 🧪 @plosbiology.org plos.io/40SR4kj