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Posts by Paul Daly

Please have a look at our recent work on Trichoderma nordicum (a recently described species) and biocontrol of oomycete-caused crop diseases

www.mdpi.com/2309-608X/12...

8 hours ago 0 1 0 0
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📖 Read this important perspective piece in the April issue of #GENETICS that outlines the limitations of Mendelism in genotype-phenotype mapping and advocates for new experimental paradigms to understand context-dependent genetic effects.

🔗 buff.ly/4OAZJS2

5 days ago 4 1 0 0
PNAS Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

What if plant immunity doesn’t stop bacteria from arriving - but from staying?
Excited to share our new Dangl Lab paper (doi.org/10.1073/pnas.2535583123), asking a fundamental co-evolutionary question: which flagellar function is targeted by plant immunity?
#Coevolution #Plant-Microbiome #PNAS
🧵1/8

3 weeks ago 52 29 2 1
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Ever wondered how the #cuticle, a hallmark of land plants, was established?

In our latest study, we show that the CUTIN SYNTHASE enzyme family was a key driver of this evolutionary innovation. #plantscience

▶️ www.biorxiv.org/content/10.6...

A thread 🧵 [1/8]

3 weeks ago 88 39 4 1

The transcription factor SiROCX controls a monocot-specific CAZyme program for host cell wall remodeling during symbiotic root colonization www.biorxiv.org/content/10.64898/2026.03...

1 month ago 1 1 0 0
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And so it begins!!! #Fungal26 is underway!

Thanks to the great work of Antonis Rolas @rokaslab.bsky.social and Meritxell Riquelme

1 month ago 12 2 0 0

Construction of a randomly barcoded insertional mutant library in the filamentous fungus Trichoderma atroviride www.biorxiv.org/content/10.1101/2025.11....

4 months ago 3 1 0 1

Calling all OrthoFinder users!

We’ve just released GLADE, a tool to infer gene gains, losses, duplications, and ancestral genomes across a phylogeny.

GLADE runs directly on OrthoFinder results.
www.biorxiv.org/content/10.6...
github.com/lauriebelch/...

(1/10)

2 months ago 104 48 1 2
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Warfare among rice sheath pathogens: Rhizoctonia solani AG 1-IA neutralizes Pseudomonas fuscovaginae cyclic lipopeptides | Applied and Environmental Microbiology Rice is a global staple crop that is susceptible to various pathogens, including Pseudomonas fuscovaginae, causing sheath brown rot, and Rhizoctonia solani AG 1-IA, which causes sheath blight. Notably...

Warfare among rice sheath pathogens: Rhizoctonia solani AG 1-IA neutralizes Pseudomonas fuscovaginae cyclic lipopeptides

#ApplEnvironMicrobiol by Jasmine De Rop from Monica Höfte at @fbwugent.bsky.social

journals.asm.org/doi/10.1128/...

3 months ago 7 2 0 0

Please take a look our recent method paper (please DM me for full text)

Rapid detection of Pythium soft rot in ginger (Zingiber officinale) caused by Pythium myriotylum using LAMP | Plant Disease apsjournals.apsnet.org/doi/10.1094/...

3 months ago 2 0 0 0
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The changing roles of Escherichia coli Nature Microbiology - Richard Lenski traces the legacy of Escherichia coli and how science is evolving to use this model organism in new ways.

"The changing roles of Escherichia coli" -- a short essay by yours truly.

rdcu.be/eVtXT

4 months ago 164 59 1 4
Illustration of a clinical therapy setting in which a clinician sits at a desk holding playing cards while a computer screen displays a LLM prompt reading, ‘How does that make you feel?’ A patient lies on a couch in the background, conveying a conceptual commentary on the use of artificial intelligence in therapy.
Image credit: Dave Cutler (artist).

Illustration of a clinical therapy setting in which a clinician sits at a desk holding playing cards while a computer screen displays a LLM prompt reading, ‘How does that make you feel?’ A patient lies on a couch in the background, conveying a conceptual commentary on the use of artificial intelligence in therapy. Image credit: Dave Cutler (artist).

Opinion: The “machinal bypass” examines how #AI can replace—not augment—our own presence. From #researchers to #clinicians, what happens when we let machines stand in for ourselves? In PNAS Front Matter: https://ow.ly/Tro450XLB5q

#AI #psychology #psychiatry #MentalHealth #LLM

4 months ago 3 2 0 0
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Mapping the Earth’s Hidden Fungal Kingdom | Joint Genome Institute Leveraging massive comparative genomics to decode millions of mystery genes and lay a future-ready foundation

“The enormous diversity of fungal genomes...offers catalogs of enzymes, secondary metabolites & other parts lists for biotechnology, bioenergy & biomaterials."—Igor Grigoriev, Fungal & Algal Program Head.
🖥️🧬🍄🍄‍🟫

jgi.doe.gov/user-science/science-sto...

4 months ago 7 2 0 0
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How #fungi sense and respond to light.

Primer in our current issue👇

www.cell.com/current-biol...

4 months ago 29 8 0 1
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Cell wall patterning regulates plant stem cell dynamics The plant cell wall regulates development through spatiotemporal modulation of its chemical and mechanical properties. Pectin methylesterification is recognized as a rheological switch controlling wal...

Out in @science.org this week:
PME5 is sequestered in the nucleus and released during cytokinesis allowing its activity to be timed with cell division.

www.science.org/doi/10.1126/...

#PlantScience
#PlantSci

4 months ago 52 22 0 1
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Helixer: ab initio prediction of primary eukaryotic gene models combining deep learning and a hidden Markov model - Nature Methods By leveraging both deep learning and hidden Markov models, Helixer achieves broad taxonomic coverage for ab initio gene annotation of eukaryotic genomes from fungi, plants, vertebrates and invertebrat...

AI model Helixer predicts eukaryotic genes ab initio, directly from a plain text FASTA file.

No RNA-seq.
No protein homology.
No repeats, hints, or curated evidence.

Raw genome → accurate gene models.
Deep learning + HMM, published in @natmethods.nature.com

www.nature.com/articles/s41...

4 months ago 71 32 3 2
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Congrats to the prize winners at Asian Mycological Congress #AMC2025 #mycology #fungi

4 months ago 5 0 0 0
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Keynote talk from Zhensheng Kang at #AMC2025 on wheat stripe rust. Very interesting pathogen life cycle.

4 months ago 1 0 0 0
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Great to present at #AMC2025 in session with @sunilmundra.bsky.social @qurban38.bsky.social Sakae Horisawa and Feng Cai

4 months ago 1 0 0 0
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Starship transposons, HGT on ToxA from Fei Liu from CAS at #AMC2025

4 months ago 2 0 0 0
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Interesting talk from Marta @mf-s.bsky.social at AMC 2025 #AMC2025 on astromycology

4 months ago 2 0 1 0
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Lots of tools & resources for Cordyceps militaris for gene editing from Caihong Dong at #AMC2025

4 months ago 1 0 0 0
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Interesting talk at AMC 2025 #AMC2025 from Arend van Peer on incompatibility in mushrooms

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Interesting keynote talk from Chengshu Wang at AMC 2025 #AMC2025

4 months ago 2 0 0 0
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Interesting opening talk of AMC 2025 from Marc Stadler @ms-fungi.bsky.social

4 months ago 1 0 0 0
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AMC 2025 starting today in Guangzhou, China with next-gen mycologists symposium. lots of details of the schedule on website www.amc2025.cn

#AMC2025

Big life-size schedule

4 months ago 2 0 0 0

Check it out!

5 months ago 9 3 0 0
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Demystifying fungal systematics: A gateway to fungal literacy and societal/ecological relevance through familiar species Fungal systematics can feel overwhelming given the vast species diversity within this kingdom, with numerous subgroups at every taxonomic rank. This often creates a disconnect between the undertsnidn...

We are delighted to let you know that your Plants, People, Planet article 'Demystifying Fungal Systematics: A Gateway to Fungal Literacy and Societal/Ecological Relevance Through Familiar Species' has been published on Early View.

nph.onlinelibrary.wiley.com/doi/10.1002/...

5 months ago 32 22 0 1

Please take a look at our latest work on regulation in Trichoderma harzianum in response to oomycete cell walls

Share link (free access until end Dec 2025): authors.elsevier.com/a/1m55I3MmJP...
See also from here: doi.org/10.1016/j.mi...

5 months ago 2 1 0 0
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Beware giving this site your unpublished data Users noticed the website had fake testimonials and a domain name registered seemingly overnight.

PSA: Many of you may have noticed a website floating around called formatmypaper(dot)com. People rightly noted something was fishy. I dig into what happened here:
open.substack.com/pub/ubadah/p...

5 months ago 32 23 1 2