In any case, it's important to remember that the CD was just a theoretical framework; something put together when we knew very little, which was useful for stating problems clearly and thus guiding experiments. If we do find things that "break" it, great!
Announcement for Immunology 2026 attendees about room changes for sessions LYM5, MPF2, LYM6, CAREER/NET18, TIME4, and MPF3.
Stay in the loop! 📢 Make sure to refresh your AAI Events mobile app right now to see the most up-to-date room changes and schedule updates. Don't miss a beat (or a session)!
The number of grant applications is rising sharply. Our capacity for their evaluation isn’t.
ERC President Maria Leptin explains why stricter resubmission limits are being introduced for 2027 calls and what they mean for applicants.
🔗 link.europa.eu/xF7kjc
How does the immune system respond to the world around it? #LIG26
Early bird registration and abstract submission are open for this one-day London event exploring how environmental inputs are sensed, integrated, and translated into immune responses.
🔗 vist.ly/4ysjf
I'm looking for #NewPIs (<3 years as lab heads) in the gene regulation/functional genomics space. If you are one or know one, please comment below! 🧪
Skin inflammation and itch response are independently regulated by distinct nociceptor subsets @cp-immunity.bsky.social
www.cell.com/immunity/ful... @inserm.fr
We invite researchers from around the world to showcase their 3Rs achievements on the global stage by applying for our annual NC3Rs 3Rs Prize: nc3rs.org.uk/internationa...
Somatic mutations in autoimmune lymphocytes may allow them to escape tolerance constraints through a polyclonal cascade of somatic evolution @nature.com @sangerinstitute.bsky.social @ims-mrl.bsky.social @cuh.nhs.uk @imartincorena.bsky.social
www.nature.com/articles/s41...
Banner shows the pint of science logo and the dates for the 2026 NC3Rs sponsored events: Newcastle 18 May, Bristol 19 May, London 20 May.
We are thrilled to be returning to @pintofscience.uk for our twelfth year as festival sponsors! Join us in Newcastle, Bristol and London as NC3Rs-funded scientists showcase innovations in replacement approaches and explore the future of alternatives to animals. 🎟️ pintofscience.co.uk/sponsor/nc3rs/
Wildlife trade drives animal-to-human pathogen transmission over 40 years
New in @science.org ‼️ In the most comprehensive study to date, we show that wildlife trade is driving animal-to-human zoonotic spillover at a planetary scale, with +1 spillover per host every 10 years. Live animal markets and illegal trade pose even greater risks. 🔓 www.science.org/doi/10.1126/...
We have a new story out at @natcomms.nature.com!
This time our lab tackled the enigmatic "autoinflammation of unknown origin". These #autoinflammatory patients don't fit the criteria of classical syndromes. It wasn't even clear they were a single group, to be honest
www.nature.com/articles/s41...
Register for our upcoming welfare webinar focusing on habituating dogs, minipigs and non-human primates to procedures in toxicology studies to refine their use in regulatory safety assessment: nc3rs.org.uk/events/welfa...
📅 Thursday 14 May, 12.30 – 13.30 (GMT)
📜 Certificates of attendance available
Announcement for a lecture by Clemens Plaschka from Vienna's Research Institute of Molecular Pathology on mRNA packaging and export, scheduled for Monday 27th April at 11am BST.
On 27th April, we’ll be welcoming Clemens Plaschka back to the LMB to present an #LMBSeminar on ‘Mechanisms of mRNA packaging and export’
Clemens, previously an LMB postdoc, is now a Senior Group Leader at IMP, Vienna - @plaschkalab.bsky.social.
Talk details: mrclmb.ac.uk/news-events/...
Job opportunity for a #FlowCytometry technician, School of Biology, University of Edinburgh, UK. We do cool flow with fungi, bacteria, diatoms, space particles, as well as mammalian cells. Spectral, conventional and sorts. Join us! Details here: elxw.fa.em3.oraclecloud.com/hcmUI/Candid...
Check out this new work from @ckylau.bsky.social and @ritatewari.bsky.social labs on proteins that bridge Plasmodium cytoskeleton and it's motility apparatus. Congrats to all authors!!
PD-1 promotes the survival of both IEL precursors and thymocytes destined for other fates, while the downregulation of CD8-β is a hallmark of autoreactive MHC I-restricted thymocytes that survive negative selection @immunohorizons.bsky.social
academic.oup.com/immunohorizo...
Cristina Rada holding a coffee mug in a bright office with a computer and bookshelves behind her.
Group of seven posing indoors against a vertical blind backdrop in a relaxed setting.
Cristina Rada and Michael Neuberger collaborating and writing mathematical equations on a whiteboard.
From joining the LMB as a student with César Milstein in 1989, to overseeing over 100 PhD students at any one time as Director of Studies, Cristina Rada has certainly had a varied career at the LMB.
Read her recollections of life at the LMB here: mrclmb.ac.uk/careers-and-...
This is a great paper - even down to the honest way the authors critique their own findings in the final sentence of the results
www.nature.com/articles/s41...
Here you have some of the best examples of scientists and colleagues you can find!
I have been unreasonably fortunate to work with some extremely clever and notably kind people during my career so far. Katerina is a prime example of such. Whilst I obviously cannot guarantee the outcome of any endeavour, I'll be damned if I don't recommend this PhD opportunity most wholeheartedly!
Tuft cells shape airway remodeling by eliciting OXGR1- and SOX9-dependent stem cell programs
www.nature.com/articles/s41... @natcomms.nature.com @harvardmed.bsky.social
Excited to share our work on the structure and function of cytoplasmic lattices within mouse embryos. A collaborative effort with @niakanlab.bsky.social and work led by @kashishsingh.bsky.social and @inaharasimov.bsky.social . It is now out on BioRxiv: www.biorxiv.org/content/10.6...
Aging disrupts sympathetic innervation of the thymus @cp-cellreports.bsky.social @einsteinmededu.bsky.social @maryanovichlab.bsky.social
www.cell.com/cell-reports...
In vivo screening reveals new regulators of Natural Killer cell development and functional response to acute cytomegalovirus infection
www.biorxiv.org/content/10.6...
Kate McDole, Group Leader in @cellbiol-mrclmb.bsky.social joins The Light-Sheet Chronicles podcast to talk building light-sheet microscopes, imaging development and why errors always occur in the middle of the night.
Listen here: youtu.be/tAjlZ6by0P8?...
#LMBintheNews
Commensal-driven serotonin production modulates in vivo delivery of synthetic and viral vectors @science.org
www.science.org/doi/10.1126/...
Great paper by Lucas Albacete, @simonbullock11.bsky.social, @marta-shahbazi.bsky.social at @cellbiol-mrclmb.bsky.social @mrclmb.ac.uk.
Coordinated stress response!
www.biorxiv.org/content/10.6...
So happy to see this out! Reañly cool!!! Congrats, Katie & Kate!
Microscopic view of a glowing, irregularly shaped primordial germ cell with long protrusions with purple and green fluorescence against a dark blue background.
How do primordial germ cells (PGCs) migrate across a developing embryo?
#LMBResearch from Katharine Goodwin and Kate McDole (@cellbiol-mrclmb.bsky.social) uncovers the mechanisms PGCs use in mouse embryos to navigate this long and surprisingly risky journey.
Read more: mrclmb.ac.uk/news-events/...
