Cell-type-targeted mitochondrial transplantation rescues cell degeneration - Nature MitoCatch is a cell-type-specific mitochondrion-targeting system that links mitochondria and the cell surface by protein binders and delivers mitochondria into the target cell.

Last 2 weeks of research on #Mitochondria in #Health and #Disease! 📚
biomed.news/bims-mitdis/...
biomed.news/bims-mitdis/...

Among highlights 👇
www.nature.com/articles/s41...

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Pearling drives mitochondrial DNA nucleoid distribution The distribution of mitochondrial DNA–containing nucleoids is essential for mitochondrial function and genome inheritance; however, no known mechanisms can explain nucleoid segregation or their regula...

Easter edition of #Mitochondria in #Health and #Disease!
🐰🐣
biomed.news/bims-mitdis/...

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Perling drives mtDNA nucleoid distribution
www.science.org/doi/10.1126/...

https://www.nature.com/articles/s42255-026-01476-1

Latest published research on #Mitochondria in #Health and #Disease! 📚 #week13
biomed.news/bims-mitdis/...

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PLIN5 phosphorylation orchestrates mitochondria lipid-droplet coupling to control hepatic lipid flux and steatosis

Mitochondrial control of glycerolipid synthesis by a PEP shuttle https://www.cell.com/cell/abstract/S0092-8674(26)00224-2?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0092867426002242%3Fshowall%3Dtrue

#Mitochondria in #Health and #Disease - last 2 weeks of published research 📚:
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biomed.news/bims-mitdis/...

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Mito control of glycerolipid synthesis by a PEP shuttle
www.cell.com/cell/abstrac...

Vitamin B2 and B3 nutrigenomics reveals a therapy for NAXD disease A nutrigenomics framework identifies genetic diseases amenable to vitamin B2 and B3 therapies. This approach nominates vitamin B3 as a therapy for NAXD deficiency, a lethal neurodevelopmental disorder...

Last 2 weeks of literature on #Mitochondria in #Health & #Disease! 🤍 💚
biomed.news/bims-mitdis/...
biomed.news/bims-mitdis/...

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Vit B2 and B3 nutrigenomics reveals a therapy for NAXD disease
www.cell.com/cell/fulltex...

Rare Disease Day – 28 February 2026
Let’s unite to improve diagnosis and understanding of mitochondrial disease.

These rare conditions can affect any organ, at any age, impacting at least 1 in 4,000 people. Greater awareness and research are vital.

#RareDiseaseDay #MitochondrialDisease

A genetically encoded bifunctional enzyme mitigates redox imbalance and lipotoxicity - Nature Metabolism The authors present a genetically encoded tool based on a bifunctional enzyme that can regenerate NAD+ while executing an engineered glycerol shunt. The tool successfully restored redox imbalance and ...

A wonderful collection of literature from #week8 on #Mitochondria in #Health & #Disease! 📚

biomed.news/bims-mitdis/...

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A [...] bifunctional enzyme mitigates redox imbalance and lipotoxicity
www.nature.com/articles/s42...

The next big thing in wellness is…mitochondria? People are suddenly very concerned about the powerhouse of the cell.

The next big thing in wellness is mitochondrial health.
www.vox.com/advice/47803...

Mitochondrial superoxide regulates nuclear envelope integrity and ageing via redox-mediated lipid metabolism - Nature Metabolism Mitochondrial superoxide production is shown to preserve nuclear envelope integrity by controlling lipid peroxidation, with impact on nuclear and organismal ageing in C. elegans.

A new collection of papers on #Mitochondria in #Health and #Disease! #MitochondrialDisease 📚
biomed.news/bims-mitdis/...

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Mt superoxide regulates nuclear integrity and ageing via lipid metab

www.nature.com/articles/s42...

Mitochondria painting - without the pain(t). Unvarnished mitochondrial biology, live, and at scale.

A new collection of papers from #week5 on Mitochondria in Health & Disease! #MitochondrialDisease
biomed.news/bims-mitdis/...

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Among highlights
www.nature.com/articles/s41...

https://academic.oup.com/nar/article/54/2/gkag008/8433879?login=false

A new collection of papers on Mitochondria in Health and Disease! #week3 #MitochondrialDisorders
biomed.news/bims-mitdis/...

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Human mitochondrial helicase Twinkle has RNA binding, annealing, and strand-exchange activities

Hexokinase detachment from mitochondria drives the Warburg effect to support compartmentalized ATP production - Nature Metabolism Hexokinase detachment from the outer mitochondrial membrane is shown to support aerobic glycolysis in cancer cells. Differential localization of the HK1 isoform to the outer mitochondrial membrane, co...

Latest collection of papers on mitochondria in health and disease! #MitochondrialDisease #week3

biomed.news/bims-mitdis/...

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www.nature.com/articles/s42...

I asked AI to describe my contribution to the mitochondrial field. Received this. It's quite impressive and pretty accurate.

Excited to speak at the symposium “Artificial Intelligence in Mitochondrial Medicine”

🧬 Exploring how AI is transforming mitochondrial medicine
📍 Pisa, Italy | 🏨 Hotel Galilei
📅 Jan 23, 2026

#AIinMedicine #MitochondrialMedicine #DigitalHealth #PrecisionMedicine

Mitochondrial control of fuel switching via carnitine biosynthesis Environmental adaptation often involves a shift in energy utilization toward mitochondrial fatty acid oxidation, which requires carnitine. Besides dietary sources of animal origin, carnitine biosynthe...

Last 2 weeks of research papers relevant to #MitochondrialDisease!
biomed.news/bims-mitdis/...
biomed.news/bims-mitdis/...

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Mitochondrial control of fuel switching via carnitine biosynthesis
www.science.org/doi/10.1126/...

Recommendations for mitochondria transfer and transplantation nomenclature and characterization - Nature Metabolism This Consensus Statement provides a nomenclature framework and experimental recommendations for studying mitochondrial transfer and transplantation.

Reviews/Perspectives Top #Citations 2025: 🥇🧪

Jonathan Brestoff (Washington U Dept Med), Keshav Singh (@mitoscientist.bsky.social, U Alabama) et al.

Recommendations for mitochondria transfer and transplantation nomenclature and characterization

Recommendations for mitochondria transfer and transplantation nomenclature and characterization - Nature Metabolism This Consensus Statement provides a nomenclature framework and experimental recommendations for studying mitochondrial transfer and transplantation.

Reviews/Perspectives Top #Altmetric 2025: 🥇🧪

Jonathan Brestoff (Washington U Dept Med), Keshav Singh (@mitoscientist.bsky.social, U Alabama) et al.

Recommendations for mitochondria transfer and transplantation nomenclature and characterization

🌹🌹May all that is beautiful and meaningful and brings you and your family joy be yours throughout the coming year! Wish you a very happy new year!🌹🌹

End-of-year selection of papers on #MitochondrialDisease! 📚
biomed.news/bims-mitdis/...

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Have a great 2026! ✨

Mitochondria are among nature's most remarkable gifts to us. These tiny powerhouses are essential for providing
energy and stand at the forefront of anti-aging science, serving as the driving
force behind strategies to promote healthy longevity.

🍃 🏛️ ✏️ 🧪 Forgotten NIH Required Attachments for Applications
Dec 22, 2025

Death By a Thousand Cuts Capstone Archive Submission YouTube video by Usha Sookai

Powerful short documentary about the researchers affected by NIH grant terminations and broad extortion of universities.

youtu.be/DaTOmUZHeik

1/2

A woman scientist is reading books in the library.

Christmas edition🎄of #MitochondrialDisease collection of papers! 🎁 📚
biomed.news/bims-mitdis/...

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Fuel your mitos well and happy holidays!

It's an honor to see Yuva Biosciences and our contributions in the field featured in this mitochondrial story in The Washington Post today.

https://www.cell.com/cms/10.1016/j.cell.2025.11.002/asset/6a29b9bb-e6a4-4eb7-a86a-b1f1f5fd697f/main.assets/fx1_lrg.jpg

Such a great collection of papers on #mitochondrialdisease from #week49! 📚 Congratulations to all authors! biomed.news/bims-mitdis/...
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Innate immune and metabolic signals induce mitochondria-dependent membrane lysis via mitoxyperiosis
Wang et al

https://www.cell.com/cell/abstract/S0092-8674(25)01242-5?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0092867425012425%3Fshowall%3Dtrue

#mitochondrialdisease collection of papers from #week48! 📚
biomed.news/bims-mitdis/...

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Inhibition of oligomeric BAX by an anti-apoptotic dimer
Newman et al