A new #OpenAccess paper provides first global estimates of the impact of fortification on dietary micronutrient adequacy, finding 38.6bn inadequate person-nutrient intakes, and models cost-effectiveness of aligning standards and improving compliance on fortification www.thelancet.com/journals/lan...

Reopening the humanitarian corridor from Gaza to the West Bank and East Jerusalem for medical evacuations In late November, 2025, five human rights organisations petitioned the Israeli High Court of Justice to allow for the evacuation of patients from the Gaza Strip into the West Bank and East Jerusalem. ...

A new @lancetgh.bsky.social article from CISAC professor Tom Dannenbaum and colleagues urges reopening humanitarian access to Gaza, warning of severe consequences for civilian health and care delivery.
www.thelancet.com/journals/lan...

Lancet Global Health: The lenacapavir paradox: why a promising prevention tool raises difficult questions about African HIV response priorities

by Reuben Granich
@lancetgh.bsky.social

▶️ bit.ly/4m9E6sJ

Energy and health in low-income and middle-income countries Reliable and affordable clean energy is essential for modern living and powering economies. Access to clean energy has increased substantially in low-income and middle-income countries over the past t...

Have you read our huge new #OpenAccess Series of papers on energy and health in LMICs yet? From the health burden of polluting household cooking fuels to equitable and reliable electricity access in health-care facilities, energy is a health intervention. www.thelancet.com/series-do/en...

Madhukar Pai on tuberculosis Podcast Episode · The Lancet Global Health in conversation with · March 16 · 36m

And our podcast for this month is a chat with @madhupai.bsky.social on what we're getting wrong about tuberculosis and how to fix it: #WorldTBDay
Apple: podcasts.apple.com/us/podcast/m...
Spotify: open.spotify.com/episode/3kJy...

Tuberculosis at a crossroads This World Tuberculosis Day, as ever, the world has everything it needs to end tuberculosis in our lifetimes. Yet in 2024, 1·23 million people died of tuberculosis, indicating that tuberculosis persis...

Our editorial this month is entitled "Tuberculosis at a crossroads" - what now for tuberculosis programmes and global solidarity? #WorldTBDay www.thelancet.com/journals/lan...

The tuberculogenic environment Tuberculosis persists as the world's deadliest infectious disease, despite improved diagnostics and effective treatment. The tuberculogenic environment describes the sum of influences, vulnerabilities...

This #WorldTBDay here are some recent bits from us to think about:

First, Mikaela Coleman and colleagues argue for reframing tuberculosis as a complex systems problem, in their Health Policy on the tuberculogenic environment www.thelancet.com/journals/lan...

Madhukar Pai on tuberculosis - The Lancet Global Health in conversation with What systems fix would unlock the biggest equity gains? Should countries target patients with TB or conduct universal interventions? What does self-reliance look like post-aid cuts? Madhukar Pai joins...

#WorldTBDay @lancetgh.bsky.social podcast on tuberculosis, with host @gavincleaver.bsky.social

www.buzzsprout.com/1358155/epis...

Added value of this study Our analysis exploits a balanced 156-country panel (2000–22; 3588 observations) that pairs population-weighted temperature distributions with WHO-harmonised inactivity data. By applying a fixed-effects, non-linear bin model and extensive robustness checks, we estimate exposure–response functions: each extra month >27·8°C raises inactivity by 1·44 percentage points globally and 1·85 percentage points in low-income and middle-income countries, with hotspots exceeding 4 percentage points across Central America, the Caribbean, eastern sub-Saharan Africa, and equatorial southeast Asia. Integrating these exposure–response functions with the Coupled Model Intercomparison Project-6 projections yield the first physical inactivity forecasts to 2050, translating projected heat exposure into additional deaths and productivity losses. Our study therefore contributes to the geographical, temporal, and policy evidence that can inform climate-resilient action in global health. Implications of all the available evidence Taken together, current evidence and our new findings indicate that rising temperatures will lead to substantial increases in physical inactivity-related health and economic burdens—by 2050 we project 0·47–0·70 million additional premature deaths annually and $2·40–3·68 billion in productivity losses under plausible climate scenarios (SSP1–2.6 to SSP5–8.5), equivalent to 7·19–10·73 percentage points of 2022 physical inactivity-attributable deaths (6·52 million) and 5·12–7·85 percentage points of 2022 physical inactivity productivity losses ($46·92 billion). Heat-responsive urban design, subsidised climate-controlled exercise facilities, and integration of heat risk messaging into physical activity guidelines emerge as immediate adaptation priorities, while ambitious mitigation is essential to avert a heat-driven sedentary transition. Future research should couple subnational accelerometer surveillance with high-resolution climate projections…

New in this month's issue:

Christian Garcia-Witulski and colleagues quantify the effect of climate change on physical activity, finding that every additional month with a mean temperature above 27.8°C results in a 1.44% rise in physical inactivity globally www.thelancet.com/journals/lan...

Added value of this study Our analysis exploits a balanced 156-country panel (2000–22; 3588 observations) that pairs population-weighted temperature distributions with WHO-harmonised inactivity data. By applying a fixed-effects, non-linear bin model and extensive robustness checks, we estimate exposure–response functions: each extra month >27·8°C raises inactivity by 1·44 percentage points globally and 1·85 percentage points in low-income and middle-income countries, with hotspots exceeding 4 percentage points across Central America, the Caribbean, eastern sub-Saharan Africa, and equatorial southeast Asia. Integrating these exposure–response functions with the Coupled Model Intercomparison Project-6 projections yield the first physical inactivity forecasts to 2050, translating projected heat exposure into additional deaths and productivity losses. Our study therefore contributes to the geographical, temporal, and policy evidence that can inform climate-resilient action in global health. Implications of all the available evidence Taken together, current evidence and our new findings indicate that rising temperatures will lead to substantial increases in physical inactivity-related health and economic burdens—by 2050 we project 0·47–0·70 million additional premature deaths annually and $2·40–3·68 billion in productivity losses under plausible climate scenarios (SSP1–2.6 to SSP5–8.5), equivalent to 7·19–10·73 percentage points of 2022 physical inactivity-attributable deaths (6·52 million) and 5·12–7·85 percentage points of 2022 physical inactivity productivity losses ($46·92 billion). Heat-responsive urban design, subsidised climate-controlled exercise facilities, and integration of heat risk messaging into physical activity guidelines emerge as immediate adaptation priorities, while ambitious mitigation is essential to avert a heat-driven sedentary transition. Future research should couple subnational accelerometer surveillance with high-resolution climate projections…

New in this month's issue:

Christian Garcia-Witulski and colleagues quantify the effect of climate change on physical activity, finding that every additional month with a mean temperature above 27.8°C results in a 1.44% rise in physical inactivity globally www.thelancet.com/journals/lan...

Energy and health in low-income and middle-income countries Reliable and affordable clean energy is essential for modern living and powering economies. Access to clean energy has increased substantially in low-income and middle-income countries over the past t...

Our new issue is out today! In this month's edition we have an amazing new Series on #energy and health in LMICs, which covers everything from clean energy uptake to the burden of disease from energy production across five #OpenAccess papers www.thelancet.com/series-do/en...

Ahead of World Tuberculosis Day, I spoke with @gavincleaver.bsky.social for this podcast by @lancetgh.bsky.social

Spotify - open.spotify.com/episode/3kJy...

Apple - podcasts.apple.com/us/podcast/m...

Population impact of South Africa's human papillomavirus (HPV) vaccination programme on HPV prevalence in adolescent girls with and without HIV: a repeat cross-sectional study In this large-scale evaluation of South Africa's two-dose HPV vaccination programme, we observed impacts similar to those seen with three-dose programmes in high-income settings, including equivalent ...

We also have a large-scale evaluation of South Africa's HPV #vaccination programme www.thelancet.com/journals/lan...
An article on global #climate justice in LMICs www.thelancet.com/journals/lan...
And an editorial on TB at a funding crossroads www.thelancet.com/journals/lan...

Energy and health in low-income and middle-income countries Reliable and affordable clean energy is essential for modern living and powering economies. Access to clean energy has increased substantially in low-income and middle-income countries over the past t...

Our new issue is out today! In this month's edition we have an amazing new Series on #energy and health in LMICs, which covers everything from clean energy uptake to the burden of disease from energy production across five #OpenAccess papers www.thelancet.com/series-do/en...

Tuberculosis at a crossroads This World Tuberculosis Day, as ever, the world has everything it needs to end tuberculosis in our lifetimes. Yet in 2024, 1·23 million people died of tuberculosis, indicating that tuberculosis persis...

"This World TB Day, as ever, the world has everything it needs to end tuberculosis in our lifetimes. Yet in 2024, 1·23 million people died of tuberculosis, indicating that tuberculosis persists as the world's deadliest infectious disease" @lancetgh.bsky.social

www.thelancet.com/journals/lan...

Published in @lancetgh.bsky.social

Therapies based on #GLP-1 receptor agonists: significance, challenges, and opportunities www.thelancet.com/journals/lan...
#OpenAccess

#MedSky #EndoSky

Image: The first issue of The Lancet Regional Health Africa journal cover. Credit: David Sacks - Getty Images.

🆕 Out now: the inaugural issue of The Lancet Regional Health – Africa, a Gold Open Access journal.

"As a journal, we stand for the decolonization of health and medical research in Africa."

Explore the full issue 👉 spkl.io/63320AIdt8

Thank you to The Lancet Global Health's statistical and peer reviewers in 2025 The following individuals reviewed at least one paper for The Lancet Global Health in 2025, including those who co-reviewed with a colleague. We sincerely thank every one of them and hope to engage fu...

A sincere thank you to everyone who peer reviewed content for our journal in 2025, who we've listed here by name! You do so much to help us all improve research worldwide www.thelancet.com/journals/lan...

The effect of Indigenous American genomic ancestry on type 2 diabetes in Mexico: an analysis of 134 548 individuals from the Mexico City Prospective Study The percentage of inherited AMR ancestry is strongly associated with prediabetes and type 2 diabetes in this admixed Mexican population. These findings suggest that most of the Mexican population has ...

Published in @thelancetph.bsky.social

The effect of Indigenous American genomic ancestry on type 2 #diabetes in Mexico: an analysis of 134 548 individuals from the Mexico City Prospective Study www.thelancet.com/journals/lan...
#T2D #Mexico
#OpenAccess

#MedSky #EndoSky

From emergency to integration: research as the bridge in mpox control The lifting of the status of mpox as a Public Health Emergency of Continental Security (PHECS) is a major epidemiological and political milestone.1 However, this change in status should not be confuse...

A bumper crop of mpox content - 1 comment and 4 research articles 👇

From emergency to integration: research as the bridge in mpox control

www.thelancet.com/journals/lan...

Safeguarding women and girls in the age of AI As artificial intelligence (AI) technologies become increasingly embedded in global health research and practice, they offer new opportunities to address gaps in women's health, including maternal health and gender equity. Additionally, as shown by Peige Song and colleagues in this issue, AI could help identify and prioritise research directions that address the needs of marginalised groups. Yet these technologies may also be misused to amplify harm and perpetuate inequities. The recent Grok AI scandal, involving the non-consensual creation and dissemination of explicit sexual images of women and girls through generative AI, is a clear warning of the misuse of AI.

As AI technology becomes more embedded in everyday life, they offer opportunities to address gaps in women’s health, but also pose significant harm when misused.

A @lancetgh.bsky.social Editorial discusses how to safeguard women and girls in the age of AI: spkl.io/63328AxHOA

Three generations of women. Copyright: JOHN BIRDSALL SOCIAL ISSUES PHOTO LIBRARY/SCIENCE PHOTO LIBRARY

Our latest Editorial reflects on recent advances in women's health, as highlighted in our #InternationalWomensDay Infographic, but notes that we must remain aware of the risks of regression or misuse.
www.thelancet.com/journals/lan...
#IWD

On International Women's Day, we have published an Infographic that celebrates a decade of practice-changing research in women's health and looks forward to a new era of dedicated advocacy.
www.thelancet.com/infographics...
#IWD @thelancet.com

Figure 1 from the article, which outlines the policy areas and interventions which need change to adapt environments to enable healthy diets and active living, to create knowledge, motivation, and skills for healthy behaviour, and to transform the health system to respond to the obesity crisis

For #WorldObesityDay, two recent pieces in @lancetgh.bsky.social:
First, a Health Policy online today #OpenAccess outlines how countries signed up to the WHO Acceleration Plan to Stop Obesity can integrate and scale chronic obesity care within their health systems:
www.thelancet.com/journals/lan...

A Panel from the Comment, which reads: Panel Future directions Recommendations • Increase awareness among health-care professionals, media, and wider society of the serious health needs that GLP-1 receptor agonists exist to address, reframing public understanding of these as essential medicines to reduce multimorbidity and premature mortality • Include GLP-1 receptor agonists for use on obesity as a standalone condition (not solely as a comorbidity) in global technical guidance and the WHO Essential Medicine List • Advocate for inclusion of GLP-1 receptor agonists in national essential medicines lists and health insurance (universal health coverage) packages • Develop a global strategy to accelerate access to affordable newer treatments where more appropriate to lower-income and middle-income countries' (LMICs') health systems • Lobby global health funders and national ministries of health and finance to allocate funding to enable capacity strengthening for health-care professionals on obesity care • Include obesity within undergraduate, postgraduate, and continuing medical curricula

And we also have a Comment on GLP-1 receptor agonists and how they might fit into the wider obesity agenda, looking at their potential role in LMIC health systems and ensuring equitable access

#WorldObesityDay

www.thelancet.com/journals/lan...

Figure 1 from the article, which outlines the policy areas and interventions which need change to adapt environments to enable healthy diets and active living, to create knowledge, motivation, and skills for healthy behaviour, and to transform the health system to respond to the obesity crisis

For #WorldObesityDay, two recent pieces in @lancetgh.bsky.social:
First, a Health Policy online today #OpenAccess outlines how countries signed up to the WHO Acceleration Plan to Stop Obesity can integrate and scale chronic obesity care within their health systems:
www.thelancet.com/journals/lan...

A paragraph from the article, which reads: Under the America First Global Health Strategy, however, health cooperation is explicitly subordinated to geopolitical calculation. As the State Department makes clear; “the President and Secretary of State retain the right to pause or terminate programs which do not align with the national interest”.3 In this context, political divergence or non-compliance does not unfold gradually. It occurs abruptly, unevenly, and often without institutional recourse. The suspension of crucial HIV funding to South Africa illustrates this shift. Citing diplomatic positions on major conflicts, land expropriation laws, and alignment with alternative geopolitical blocs, the USA has shown how political alignment now overrides epidemiological logic.4 Disease burden, programmatic performance, and technical capacity provided no insulation. A high-capacity health system was exposed to withdrawal without buffers, timelines, or negotiated safeguards. For many low-income and middle-income countries, the central risk is no longer inefficiency or reform failure. It is abandonment.

A new Comment in The Lancet Global Health lays out the necessary strategic shifts to protect global health in the era of "America First", covering:

- Institutional cooperation
- Legal counterweights
- Redefining the role of multilateral institutions

www.thelancet.com/journals/lan...

Protecting global health in the era of the America First Strategy As Washington recasts its global health agenda, the America First Global Health Strategy (AFGHS) presents itself as a corrective to decades of aid dependence.1 Open-ended assistance is replaced with t...

"The policy challenge is therefore not how to restore a depoliticised global health order, but how to protect health systems in an environment in which leverage determines engagement and continuity." powerful piece in @lancetgh.bsky.social from Nelson Evaborhene www.thelancet.com/journals/lan...

Prevalence estimates of small vulnerable newborns in China (2012–22): a modelling study Although the prevalence of SVNs in mainland China has stabilised overall, a reversal occurred after 2018, with western provinces showing substantially higher levels than central and eastern provinces....

New modelling study on small vulnerable newborns (SVNs) in China 2012-2022 draws on data from over 14 million livebirths across 30 provinces to show stable but persistently high national SVN prevalence with marked subnational heterogeneity - read #openaccess here: www.thelancet.com/journals/lan...

Gaps in government recognition of the service needs of women who experience intimate partner violence: a comparative case study analysis of policies and implementation across eight countries Intimate partner violence (IPV) is a substantial health and human rights concern. Governmental policies to address IPV are well-documented, but most available evidence on implementation focuses on spe...

On violence against women, a large gap between laws & their implementation exists. Yet we have few tools to measure it. Our @lancetgh.bsky.social article draws on admin & survey data on IPV survivors to assess the “recognition gap” across countries www.thelancet.com/journals/lan... @giga-hamburg.de