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Posts by cryoEM papers

Structural mechanisms of pump assembly and drug transport in the AcrAB-TolC efflux system pubmed.ncbi.nlm.nih.gov/42007677/ #cryoEM

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cryoAgent: An agentic workflow for robust and adaptive end-to-end cryo-EM image processing www.biorxiv.org/content/10.64898/2026.04.16.718662v1 #cryoEM

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Full-Length Molecular Models of Brain-Derived α-Synuclein Fibrils Reveal a Fuzzy-Coat-Mediated Mechanism for Selective Peptide Binding www.biorxiv.org/content/10.64898/2026.04.16.718707v1 #cryoEM

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Adenylyl cyclase 9 as a molecular scaffold to dissect the regulatory mechanisms of membrane adenylyl cyclases www.biorxiv.org/content/10.64898/2026.04.18.719376v1 #cryoEM

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copick: An open dataset interface and toolkit for collaborative annotation and analysis of cryo-electron tomography data pubmed.ncbi.nlm.nih.gov/41999094/ #cryoEM

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The tumour suppressor RBM5 activates the helicase DHX15 to regulate splicing pubmed.ncbi.nlm.nih.gov/41994107/ #cryoEM

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Structural and biochemical characterization of a novel inhibitor of NMNAT1, the gatekeeper of nuclear NAD + biosynthesis pubmed.ncbi.nlm.nih.gov/41993279/ #cryoEM

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Mechanism of GPR84 allosteric modulation at a helix 8-proximate site pubmed.ncbi.nlm.nih.gov/41993300/ #cryoEM

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RNA polymerase inhibitors reveal active-site motions essential for the nucleotide-addition cycle pubmed.ncbi.nlm.nih.gov/41993335/ #cryoEM

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Structural determinants of endopilus assembly, stability and functional specificity in bacterial type II secretion pubmed.ncbi.nlm.nih.gov/41993355/ #cryoEM

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Structural Basis of Polypurine Track Strand Displacement by HIV-1 Reverse Transcriptase pubmed.ncbi.nlm.nih.gov/41993386/ #cryoEM

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Screening metatranscriptomes for ultrastable RNA secondary structures reveals hidden bacteriophages and novel capsid nanomaterials pubmed.ncbi.nlm.nih.gov/41993428/ #cryoEM

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VitriFlex: An Open-Source, Modular, and Customizable Robotic Platform for Cryo-EM Grid Preparation pubmed.ncbi.nlm.nih.gov/41993429/ #cryoEM

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Molecular basis for ligand-gating of the human GluD1 receptor pubmed.ncbi.nlm.nih.gov/41993446/ #cryoEM

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Structural principles of transcriptional collisions pubmed.ncbi.nlm.nih.gov/41993499/ #cryoEM

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Molecular architecture of the ciliary base in mammalian multiciliated cells pubmed.ncbi.nlm.nih.gov/41993500/ #cryoEM

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Molecular basis of nick ligation in the nucleosome by DNA Ligase IIIα pubmed.ncbi.nlm.nih.gov/41993504/ #cryoEM

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A brain-penetrant P2X7R antagonist mitigates Alzheimer's disease pathology pubmed.ncbi.nlm.nih.gov/41993524/ #cryoEM

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Nanoscale 3D Anatomy of the Western Flower Thrips Reproductive System Revealed by Volume Electron Microscopy: Extreme Miniaturization and Evolutionary Adaptations for Pest Fecundity pubmed.ncbi.nlm.nih.gov/41995254/ #cryoEM

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A robust workflow for 3D imaging of human mitochondria using cryo-electron tomography www.biorxiv.org/content/10.64898/2026.04.16.717704v1 #cryoEM

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Redox-Triggered Coupling Network Mediates Long-Range Energy Trans-duction in Respiratory Complex I www.biorxiv.org/content/10.64898/2026.04.14.716442v1 #cryoEM

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Integrating glycosylation in de novo protein design with ReGlyco Binder Design Filter www.biorxiv.org/content/10.64898/2026.04.16.718906v1 #cryoEM

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Pharmacological Rescue of Follicle-Stimulating Hormone Receptor Mutants. In vitro and In silico Studies☨ pubmed.ncbi.nlm.nih.gov/41988939/ #cryoEM

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Structural insights into inhibition mechanism of the helicase-primase complex from human herpesvirus 1 pubmed.ncbi.nlm.nih.gov/41990739/ #cryoEM

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Slow Dissociation of Nitazenes from the μ-Opioid Receptor Underlies the Challenge of Overdose Reversal www.biorxiv.org/content/10.64898/2026.04.14.718203v1 #cryoEM

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Asymmetric Hydration and Protonation Switching of Dual Aspartates Drive Flagellar Rotation www.biorxiv.org/content/10.64898/2026.04.14.718414v1 #cryoEM

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Highly Accurate Estimation of the Fold Accuracy of Protein Structural Models www.biorxiv.org/content/10.64898/2026.04.15.718808v1 #cryoEM

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Atomic structure and dynamics of the mechanosensitive channel MscL from E. coli by cryo-EM and solid-state NMR www.biorxiv.org/content/10.64898/2026.04.14.718163v1 #cryoEM

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A miniaturized MR1 metabolite display system with native-like protein features www.biorxiv.org/content/10.64898/2026.04.13.718121v1 #cryoEM

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Mutations in VCP cause Adams-Oliver syndrome with or without pulmonary hypertension pubmed.ncbi.nlm.nih.gov/41979051/ #cryoEM

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