Congratulations to Pilar for her very successful PhD defense - stay tuned for her next manuscript and fantastic quantitative microscopy :)

Congratulations to Lukas @pekarekl.bsky.social for winning the poster prize at the DGfB Molecular Biophysics meeting in Hünfeld last week 🏆 - it was a fantastic meeting with lots of interesting talks & great to catch up with colleagues and sad that we missed out on many of our Israeli colleagues.

... and finally saw that the survival fraction goes down 4-fold in presence of the peptide. Yay - this sounds like another great new adventure ahead. Great work by Kate and Pilar, 🙏 support by @tudresden.bsky.social and BMFTR. Take a look at bioRxiv to find out more 🔎: doi.org/10.64898/202... 6/6

This was a new adventure for us to develop an assay to stress bacteria 🧫 and test how good they adapt to antibiotic stress. We stress bacteria 🦠 with e.g. Ciprofloxacin and see if they adapt via a provided mobile integron system ± peptide. We determine many factors using also microscopy… 5/

…modify single amino acids to gain or lose function. It is dose dependent and works with a peptide as short as 7 aa. But wait 🫷- does it also work in bacteria? 4/

… use this to find a small molecule, which inhibits tail binding and thus destabilises the complex and reduces the ability to adapt to antibiotic stress in bacteria? Yes, and Kate 👩‍🔬 came up with a few different peptides … and we can control destabilisation … 3/

DNA elements were important for mechanics, but also protein mutations decreased recombination significantly. In particular the C-terminal extensions (the little pig-like ;) tails linking IntI1) stabilised the complex significantly and truncation reduced recombination. Hm💭 - could we maybe … 2/

Our newest bioRxiv on the bacterial integron is out (link below). 🧑‍🔬
How it started: Rising #AMR are a challenge for health. A key player is the bacterial integron. Do you remember its recombination efficiency 🧬🧬 correlated with the mechanical stability 💪 of a recombinase-DNA complex? 1/6

The Division of Biological Physics @mpipks.bsky.social seeks a Research Group Leader in #biophysics, #softmatter physics, or related areas. (Further particulars in the ad.)

Apply by the 3rd of April 2026 at pks.mpg.de/bprgl to join us in Dresden!

🌟 #MeetOurDataStewards #7: Cornelia Wetzker

Although processing and analyzing multidimensional data sets can be quite demanding, it is important to conduct research in a #FAIR manner. If you need help with data handling, feel free to contact our data stewards.

👉 nfdi4bioimage.de/help-desk/

🌟#MeetOurDataStewards #7: Cornelia Wetzker
Cornelia can help you with requests regarding research data management in general, #bioimage data handling and management e.g. in the platform #OMERO and publication in public repositories.
👉 nfdi4bioimage.de/about-us/dat...

Exciting times and new ideas to address the rise of AMR bacteria - looking forward to see how far we can push this idea with the support of the GO-Bio program.

Deadline is approaching (Feb 9) to apply for a PI position at Institut Pasteur. Come join us and contribute to an amazing scientific environment!!!

Postdoc Position: Cellular Biophysics | Radboud University Do you want to work as a Postdoc Position: Cellular Biophysics at the Faculty of Science? Check our vacancy!

Want to join the Chromatin Biophysics team? We are recruiting a postdoc!

⬇️⬇️⬇️

Apply through the website here www.ru.nl/en/working-a...

We are looking for a new technician 🥼 - initially limited with the option to a permanent position. If you are interested in molecular biology🧫, biochemistry🧬, a dynamic🕺, international🌍, welcoming science enthusiasts 🧑‍🔬 take a closer look👇 - Re-post appreciated www.verw.tu-dresden.de/StellAus/ste...

Oh this looks 🤩. #smFRET

Thanks for making all these efforts to outreach. In case anyone has questions, please do not hesitate to contact me. 📝🧑‍💻

3 more days to apply for a PhD position within our training program on biomolecular condensates 👇👇. 12 positions within our a focus from physics and theory to experimental biophysics to biology and medicine/disease.

Au revoir #mifobio2025. It was a fantastique, inspiring meeting- merci beaucoup for the invite and the great organization and all the workshops from homebuilt microscopes to the newest company developments. 🤩

I am very much looking forward to an inspiring week at #Mifobio2025 - thanks for the invite! I am counting on learning new exciting (pun intended) insights on fluorescence and happy to share our experience and vision on large throughput #smFRET .

Are you interested in Biomolecular Condensates and looking for a PhD training? Check out the 12 (!) open PhD positions (also 1 on smFRET & condensates 🙃) in Dresden @rtg3120.bsky.social @tudresden.bsky.social starting April 2026. Apply latest by 24 Oct 2025 here: dresdencondensates.org/join-us/

🔬For 22 years, we have been organizing #Mifobio "Functional Microscopy for Biology" the @cnrs.fr thematic school.

🎓 Courses, Seminars, Round Tables, Workshops. The overall theme concerns #biological_imaging in its most interdisciplinary aspects.

👉 Program: imabio-cnrs.fr

#GDRImaBio #Mifobio2025

Independent research fellowships leading to tenured positions at the John Innes Centre.

Repost = nice. Thank you very much!!!

Helmut Grubmüller

📢 We are hiring #PhD students and #Postdocs at the
@mpi-nat.bsky.social in
in the Department of Theoretical and Computational #Biophysics in Göttingen 🇩🇪! 🔗 check our current job adverts at www.mpinat.mpg.de/grubmueller and find your project. Submit your #application today! #job

Just started our @bcube-tud.bsky.social - organized Engineering Life 2025 #25EngLife conference in #Dresden! Excited to have everybody around!

🚨 #JobAlert We're looking for a new Administrative Coordinator at B CUBE @tudresden.bsky.social

Got a experience in admin + finance management? Know your way around German law + love strategic work?

Apply now ➡️ tud.link/szpsam
🗓️ Deadline: Aug 21

#Jobs #ScienceJobs #Dresden #CMCB #TUDresden

Few spots left on our @bcube-tud.bsky.social organised hashtag #Symposium:
Engineering Life 2025: Origin and Function of Mechanical Forces in Biology ⚙️🧬

📆 September 1-3, 2025
📍 Steigenberger Hotel de Saxe, Dresden

Register now (Deadline 31 July 2025): engineering-life-dresden.de

Enzymatic Oxygen Scavenging for Photostability without pH Drop in Single-Molecule Experiments Over the past years, bottom-up bionanotechnology has been developed as a promising tool for future technological applications. Many of these biomolecule-based assemblies are characterized using variou...

Curious to try it out - also: a non-acidifying alternative to GOC and PCD is Pyranose oxidase which we described here doi.org/10.1021/nn30... - maybe this helps you as well.

🚨 #JobAlert. please share: The DRESDEN-concept Genome Center (DcGC) 🧬 @dcgenomecenter.bsky.social is looking for the new Head of Facility!

🗓️ Deadline for applications: August 11

More information here ➡️ tud.link/fz5hr8

@tudresden.bsky.social @mpi-cbg.de

Merci @amazeld.bsky.social et Kévin for the great discussions and time during my short visit @institutpasteur.bsky.social. Always enjoyable to be in Paris.

🔥 Job alert! We are looking for an enthusiastic PhD candidate in the new Chemical Glycobiology Lab at @tudresden.bsky.social! Master in Chem or similar, experience in organic chem including chemoenzymatic, and most importantly: enthusiasm!

Deadline 8th July:

www.verw.tu-dresden.de/StellAus/ste...