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Posts by Charlotte Wright

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Social dinner: where science meets fish and chips at Cambridge ๐ŸŸ๐ŸŸ๐Ÿป๐Ÿ˜€ Our stay ended- but the real takeaway? Two weeks of #HiC #genomic mapping, now safely packed into our brains ๐Ÿงฌ ๐Ÿง โ˜บ๏ธ โ€ฆ and already in use at home๐Ÿ‘ฉ๐Ÿผโ€๐Ÿ’ป๐Ÿง‘๐Ÿปโ€๐Ÿ’ปโ˜บ๏ธ @10klepgenomes.bsky.social

1 month ago 1 1 0 0
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We are thrilled to announce the next ECR (and apparently butterfly)-themed session of the Integration of Speciation seminar, featuring @charlottewright.bsky.social and @thymelicus.bsky.social + careers Q&A with Dr Sally Potter. Find the link on the Ios website & mailing list.

1 month ago 16 13 0 2

Chromosomes are often classified as either monocentric (single centromere per chr) or holocentric (centromeric activity spread across each chr).

In reality, there is a continuum in centromere organisation - and cyperids are a fascinating system to explore this in as James shows in this preprint! ๐ŸŒฑ

1 month ago 14 5 0 0
seminar announcement with photos of speakers and talk titles

seminar announcement with photos of speakers and talk titles

The integration of speciation seminar series is restarting, with the first session coming up on *Tuesday March 3rd @ 5pm CET*, featuring two talks by @naturalselection.bsky.social and @andreaestandia.bsky.social + career Q&A with @markravinet.bsky.social as part of the ECR in Speciation theme.

1 month ago 31 20 1 2
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New pre-print with some updates on ivory:miR193 in a highly polymorphic moth.

www.biorxiv.org/content/10.6...

We mapped ivory (again!?) this time controlling aspects of camouflage in Anticarsia gemmatalis. Mapping, SVs, Expression and Function.

Comments/suggestions welcome!

1 month ago 35 14 0 2

This wide-ranging review was a true team effort that synthesises so many areas because of the diverse expertise of @vmshirey.bsky.social, @lepphylo.bsky.social, @janehillyork.bsky.social & Fabien Condamine, Naomi Pierce & Akito Kawahara (8/8)

1 month ago 4 0 0 0

Together, we highlight the remarkable progress made in understanding the ecology & evolution of Lepidoptera but also emphasise how much still needs to be done! With advances including in genomics, we predict that progress will rapidly be made towards tackling many longstanding questions! (7/8)

1 month ago 1 0 1 0

Finally, we review ongoing efforts to conserve Lepidoptera and discuss key aspects that should be prioritised in conservation efforts. We also highlight new technologies that are enhancing our ability to monitor populations including automated monitoring devices (6/8).

1 month ago 1 1 1 0
World maps that capture the geographic distribution of genera-level richness for Lepidoptera.

World maps that capture the geographic distribution of genera-level richness for Lepidoptera.

Third, we bring together previous work and publicly available occurrence data to examine patterns in geographic diversity of Lepidoptera and identify biodiversity hotspots. We also evaluate biases in how well diversity is captured globally and discuss concerning declines (5/8).

1 month ago 1 1 1 0
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Barchart that shows rapid growth in genomic resources for Lepidoptera and a count of chromosome-level genomes per superfamily.

Barchart that shows rapid growth in genomic resources for Lepidoptera and a count of chromosome-level genomes per superfamily.

Second, we chart the rapid rise in lepidopteran genomics. Genomes are driving progress in evolutionary genetics, pest management & conservation efforts. We also discuss challenges including taxonomic biases (spoiler: butterflies are v popular) and underrepresented geographic regions (4/8)

1 month ago 0 0 1 0
Phylogenies and diversification dynamics of six diverse butterfly families.

Phylogenies and diversification dynamics of six diverse butterfly families.

..we also explore the timing & drivers of lep diversification, including their relationships with plants. By comparing diversification patterns from five butterfly families, we show a general trend of increasing diversification rates towards the present - a pattern not seen in many other taxa! (3/8)

1 month ago 1 0 1 0
A time-calibrated phylogeny of lepidopteran superfamilies.

A time-calibrated phylogeny of lepidopteran superfamilies.

First, we discuss progress made in unravelling how different groups of Lepidoptera are related to each other and highlight where uncertainty remains. We also survey the estimates of when Lepidoptera originated and the challenges of using fossils to date Lepidoptera (2/8)

1 month ago 1 0 1 0
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Evolution, genomicsย and conservation of butterflies and moths - Nature Reviews Biodiversity Butterflies and moths are key indicators of functioning and healthy ecosystems around the world. This Review describes the evolutionary history of the order Lepidoptera and tracks shifts in researcher...

Now online! In this review, we cover four major topics on butterflies and moths: their evolutionary history and diversification dynamics, genomics, global diversity patterns, and conservation ๐Ÿฆ‹๐ŸŒ (1/8) @natrevbiodiv.nature.com
www.nature.com/articles/s44...

1 month ago 85 44 2 0
Participants of the workshop during Charlotte's presentation. Many screens show Hi-C maps being curated in real time.

Participants of the workshop during Charlotte's presentation. Many screens show Hi-C maps being curated in real time.

(1/3) The 2nd Genome Curation Workshop continues!

Today, participants explored Merian elements and chromosome evolution in #Lepidoptera in a fantastic talk by @charlottewright.bsky.social

More info below ๐Ÿ‘‡๐Ÿฆ‹

2 months ago 16 6 1 0
Time-calibrated phylogeny of the family Drosophilidae showing major species groups, surrounded by representative adult flies that highlight the remarkable morphological diversity of this model insect group. The composite image was created using Microsoft PowerPoint. Fly photographs were taken by Darren J. Obbard and are published under the Creative Commons Attribution License with permission.

Time-calibrated phylogeny of the family Drosophilidae showing major species groups, surrounded by representative adult flies that highlight the remarkable morphological diversity of this model insect group. The composite image was created using Microsoft PowerPoint. Fly photographs were taken by Darren J. Obbard and are published under the Creative Commons Attribution License with permission.

The #fly community aims to achieve a comprehensive genomic study of the Drosophilidae family. @pankajd.bsky.social @bernardkim.bsky.social @petrovadmitri.bsky.social @darrenobbard.bsky.social present a comparative gene annotation for 301 #Drosophilidae species @plosbiology.org ๐Ÿงช plos.io/4c3pyrI

2 months ago 10 7 0 0

It was great to start the week off by welcoming the second cohort of budding curators to the Project Psyche Genome Curation Workshop! Over the next two weeks they will become experts in piecing together genomes and will use these skills to curate some Project Psyche genomes! ๐Ÿ”Ž๐Ÿงฌ

2 months ago 14 3 0 0
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๐ŸŒJustin Gerlach's blog post traces the remarkable journey of Partula conservation from the nearโ€‘total collapse of wild populations in the 1970s, following the introduction of the predatory rosy wolf snail, to successful reintroduction efforts.

2 months ago 2 2 1 0
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Artificial nighttime lighting is suppressing moth activity Moths move significantly less when exposed to artificial nighttime light, new research shows. Mothsโ€™ attraction to artificial light, such as streetlights, is common knowledge and has been much studied...

Moths move significantly less when exposed to artificial nighttime light, new research from the Centre for Ecology and Conservation at the University of Exeter, Cornwall shows.
Read More: news.exeter.ac.uk/faculty-of-e...

@uniexecec.bsky.social #ExeterEcology

2 months ago 42 13 2 0

Yet another reason why butterflies and moths are so interesting! Unlike other studied organisms that organise their DNA into two forms of chromatin, silkworms have a mysterious third form of chromatin folding..

2 months ago 10 3 0 1
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10kLepGenomes | COST Action CA23122 The 10kLepGenomes COST Action aims to take advantage of the massive amount of data being produced by genome initiatives, in order to understand pressing issues of biodiversity loss, pest control, and ...

๐Ÿ“ฃ The 2nd #STSM call of #10kLepGenomes is complete!
Eight researchers have been awarded funding for short scientific missions to boost collaboration, training, and knowledge exchange across the network.

Congrats to the selected candidates and thanks to everyone who applied! ๐Ÿฆ‹
www.10klepgenomes.eu

2 months ago 16 7 0 1
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๐Ÿฆ‹๐Ÿงฌ A milestone for biodiversity genomics.
Project Psyche is building chromosome-level genomes for ~11,000 European butterflies & moths โ€” 1,000 sequenced, 3,000+ collected, across 34 countries.

๐Ÿ”— Read the publication: bit.ly/ProjectPsyche
@projectpsyche.bsky.social

#BiodiversityGenomics ๐Ÿงฌ๐ŸŒ

3 months ago 44 21 1 3

Always inspiring to start the year at @popgroup2026.bsky.social !
If you were there and want to learn more about pangenomes, thereโ€™s still time to register for our meeting in Edinburgh in June, co-organised with @charlottewright.bsky.social & @joanameier.bsky.social royalsociety.org/science-even...

3 months ago 9 5 0 0
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Programme - SMBE 2026 - Copenhagen Denmark SMBE 2026 Programme Days Hours Minutes Seconds CONFERENCE PROGRAMME This programme overview presents the preliminary conference program, offering a general outline of the planned sessions and activiti...

Join us at #SMBE2026 in Copenhagen this summer!

๐Ÿ”ต With @ergabiodiv.bsky.social & @official-smbe.bsky.social

๐ŸŸฃ Symposium 21 | From genomic graphs to evolutionary insights: standardising #pangenomes for population inference

๐ŸŸข smbe2026.org/programme/
#biodiversity #genomics

4 months ago 8 8 0 0
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Haplotype-Resolved Chromatin Conformation Data Reveals Relationship Between Transposable Elements and Chromosomal Pairing Abstract. Chromosomal structural changes happen when genomic stability is compromised, such as in disease or in species hybrids. In these contexts, diminis

Genutis et al. used data from an hybrid Drosophila cell line to show that pairing among trans homologous chromosomes was affected by the presence of nearby TEs. Mouse data show a similar pattern, suggesting a highly conserved TE-pairing association.

๐Ÿ”— doi.org/10.1093/gbe/evaf222

#genome #evolution

4 months ago 2 2 0 0

How does population size shape the dynamics of structural variants across the genome?
Check out our new paper in @science.org www.science.org/doi/10.1126/...

4 months ago 30 11 1 2
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Pangenomics transforms evolutionary biology | Royal Society This Theo Murphy meeting organised by Dr Joana Meier, Dr Henry North and Dr Charlotte Wright, will showcase cutting-edge pangenome tools, applied uses of pangenomes which are transforming health and a...

Are you excited about pangenomics? If so, join us in Edinburgh on 8-9th June to discuss the latest methods & insights from using these approaches across biodiversity! More details here:

royalsociety.org/science-even...

Organised together with @henrylnorth.bsky.social & @joanameier.bsky.social!

4 months ago 20 15 0 1

Our paper on ancestral conditions of caddisflies (described in the quoted post) is now out!

doi.org/10.3897/zook...

4 months ago 15 7 1 0
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Two evergreen bagworms feeding

Two evergreen bagworms feeding

One abbot's bagworm hanging out

One abbot's bagworm hanging out

Pre-print and weird repro thread time!

I've posted here about scale insects a lot, but ~half of my research is on Lepidoptera. My lab is developing bagworm moths (Psychidae) as models for comparative genomics.

You probably know them like you see in the pics below: caterpillars that make cases.

4 months ago 19 6 2 1
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How many types of butterfly can you recognise?

1000 species of butterfly and moth have been genetically sequenced, as part of a project to map the genome of all 11,665 species in Europe, co-led by Darwin Research Fellow Dr Charlotte Wright.

www.darwin.cam.ac.uk/news/sequenc...

4 months ago 1 1 0 0
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Helixer: ab initio prediction of primary eukaryotic gene models combining deep learning and a hidden Markov model - Nature Methods By leveraging both deep learning and hidden Markov models, Helixer achieves broad taxonomic coverage for ab initio gene annotation of eukaryotic genomes from fungi, plants, vertebrates and invertebrat...

We all wish peer review to be rapid and professional: doesnโ€™t always go like that. But I am relieved to finally see Helixer by @alisandra-denton.bsky.social and team published in Nature Method. Congratulations! www.nature.com/articles/s41...

4 months ago 11 5 0 1