Regulator-derived growth and fitness costs of Salmonella SPI-2 expression are environment specific and T3SS independent
www.biorxiv.org/content/10.6...

Very nice work! Really looking forward to hearing the full story next month at your seminar @ihsmumacsic.bsky.social See you then!

Preprint alert 🚨 (1/10) 🧵

𝘈𝘶𝘵𝘰𝘱𝘩𝘢𝘨𝘺 𝘪𝘴 𝘢 𝘱𝘢𝘳𝘢𝘥𝘰𝘹 𝘪𝘯 𝘱𝘭𝘢𝘯𝘵 𝘪𝘮𝘮𝘶𝘯𝘪𝘵𝘺:
It can promote resistance, susceptibility, or restrict cell death 🤯

So what is its actual role?

We show it acts as a spatial organizer of immunity across cell types 🌱🦠 #proteostasis

www.biorxiv.org/content/10.6...

📋 Join us on Friday 10th for a fascinating talk by Claude Becker from the Ludwig-Maximilians University of Munich (Germany) as part of the #IHSMLaMayoraSeminars series

Don't miss it!
🕑 9:30 AM
📍 IHSM La Mayora Auditorium

U-box E3 structural mechanisms and immune signaling networks. (a) NMR structure of the AtPUB14U-box (PDB: 1T1H, pale cyan). (b) Superimposition of the AtPUB14U-box (PDB: 1T1H, pale cyan), GmPUB13U-box (PDB: 7C96, wheat), and OsCIE1U-box (PDB: 7XED, light pink). (c) Crystal structure of the OsCIE1U-box (light pink) and OsUBC8 (light blue) complex (PDB: 7XED). (Bottom left) Close-up view of the E2-binding network with surface patch A. (Bottom middle) Close-up view of the OsCIE1U-box dimerization interface. (Bottom right) Close-up view of the E2-binding network with surface patch B. (d) Crystal structure of the GmPUB13U-box (wheat)-Avr1d (pale green) complex (PDB: 7C96). (right) Zoom-in views of the interaction network between GmPUB13U-box-Avr1d. (e) Two views of the crystal structure of the AvrPtoB CTD (C-terminal domain) (PDB: 2FD4, raspberry) showing the core fold, loops 1 and 2, and the partially disordered N-terminal domain regions. (f) Surface and cartoon representation of the AvrPtoBCTD (PDB: 2FD4, raspberry). Close-up view of the E2-binding residues. (g) Superimposition of the AtPUB14U-box (PDB: 1T1H, pale cyan) and AvrPtoBCTD (PDB: 2FD4, raspberry). Close-up view of the E2-binding residues. (h) Models of U-box E3s in positively regulating immunity. (Left) PUB2/4-interacting PTI components in Arabidopsis. (Left middle) Chitin-activated CERK1 phosphorylation of CIE1 (i), preventing E3-ligase activity and promoting the immune response as well as PUB44 and the MAPK cascade (ii), promoting PBI1 degradation and releasing WRKY45, in rice. (Right middle) PUB17-mediated degradation of KH17 in potato. (Right) Positive feedback loop by the MYC2-PUB22-JAZ4 module to promote JA signaling in tomato. (i) (Left) Secretion of SDE5 by CLas bacteria promotes PUB21-mediated MYC2 degradation and suppresses JA signaling in citrus. (Left middle) PUB25/26-mediated degradation of MYB6 and increased Verticillium dahliae susceptibility in Arabidopsis. (Right middle) PUB12/13-me…

🧬 From the plant journal: Ubiquitin ligases act as molecular switches that tune plant immunity, offering new routes to strengthen disease resistance without compromising growth. (Natalie Hamada, Katherine A. Hand, Nitzan Shabek)

▶️ onlinelibrary.wiley.com/doi/full/10....

#PlantScience #PlantBiology

Microbial communities can harbor many species that do not coexist in pairs, yet can coexist in the full community. Here we provide the mathematical foundations of emergent coexistence, and explain why it can't be predicted from pairwise tests journals.plos.org/ploscompbiol...

Interesting and important work from the @gittacoaker.bsky.social and Jie Zhu labs. There is so much to learn from spatial analyses of plant-pathogen interactions!

#ISMPMI members, our new temporary website is up, full site coming soon! In the mean time you can visit the site for membership, donation and congress information: ismpmi.org

🧑‍🚀 Nuestras nuevas titulaciones para el próximo curso: 

*Máster de Diseño, Arte y Nuevas Tecnologías: Gestión de Proyectos y Estrategias Culturales
*Máster en Biotecnología y Biología Vegetal
*Máster en Investigación e Innovación en Educación Física
*Grado en Inteligencia y Analítica de Mercados

XVIII Meeting of Plant Molecular Biology #RBMP2026
rbmp2026.com/RBMP/en/info

📅 July 1–3, 2026
📍 Bilbao, Spain

⏳ Only 1 week left!

🗓 Early registration deadline March 27

🎯 Take advantage of the early registration rate

👉 Secure your spot & share this information with colleagues

#PlantScience

On the cover: Arabidopsis thaliana ENDO-β-MANNANASE2 (AtMAN2), tagged with the fluorescent protein mRuby2 (shown in magenta), localized inside yeast cells even after removal of its predicted transmembrane domain. Pichia yeast cell walls were stained with calcofluor white (shown in cyan).

(🧵 1/2) On the cover of our #LatestIssue: the Arabidopsis thaliana ENDO-β-MANNANASE2 (AtMAN2), tagged with the fluorescent protein mRuby2 (magenta), localized inside yeast cells even after removal of its predicted transmembrane domain...

*Photomontage

My third PhD anniversary 🎂 begins as a research fellow at UMR #PVBMT from @cirad.bsky.social La Réunion. Hello #xanthomonas world 🦠🌱
Thanks to all that contributed to this goal achievement ✨

Still not in the final format but couldn't wait to share it with you, after a long jpurney to get here. Our latest work (with @davidalbesa.bsky.social lab) on Tke5 T6SS toxin from my favourite bug P. putida KT2440. 🧵 1/5 www.nature.com/articles/s42...

#theustunlab logo (by Şuayb Üstün)

On our way to the #MBP2026 meeting @theustunlab.bsky.social member @manuelgonzalezfuen.bsky.social will talk about P-bodies/immunity & @seedbarrett.bsky.social will present his project on P-bodies/ABA - since we all 💚 P-body condensates they also made it on our updated logo 😅

theustunlab.com

The Üstün Lab Visit the post for more.

We just updated our lab homepage

„Plant #Proteostasis and its role in stress adaptation“

Check it out:

theustunlab.com

Registration is now open for the EMBO Workshop "#Ubiquitin and ubiquitin-like proteins in health and disease" in #Monopoli, Italy, 28 Sep–2 Oct 2026.

Registration deadline: 31 May
Abstract submission deadline: 15 Jun

https://meetings.embo.org/event/26-ubiquitin
#EMBOubiquitin #EMBOevents 🧪

TSL Summer Conference in Plant-Microbe Interactions, 20th – 31st July… Inviting Early Career Researchers to join international experts in discussing the latest approaches and discoveries in Plant-Microbe Interactions …

Join us in Norwich this July for the TSL Summer Conference in Plant-Microbe Interactions! ☀️🌱🧬

Discuss the latest approaches & discoveries in plant health with international and local speakers.

⏰ APPLY by 30 March '26

⬇️

🔥Fantastic paper!🔥

TE with a role in vegetative phase change and gametogenesis, mediated by 24-nt siRNAs acting in trans to a wide range of genes. Found by GWAS in A. thaliana 🌱. Congratulations to the authors! 👏🏻👏🏻👏🏻
#epigenetics #plantscience
www.pnas.org/doi/10.1073/...

Next-generation proximity labeling: redefining protein interactomes Protein–protein interactions (PPIs) are fundamental to cellular function and metabolic regulation. Mapping these complex molecular networks is essential for understanding signaling pathways, yet it remains challenging due to their transient nature. We discuss how next-generation proximity labeling is evolving from bulk methods toward precise, dynamic PPI mapping, providing actionable biological insights.

Next-generation proximity labeling: redefining protein interactomes #plantscience

In Vivo Monitoring of Energy Metabolism with Genetically Encoded Fluorescent Biosensors All organisms fuel and build themselves through their energy metabolism. While classic biochemistry conceptualizes the fluxes of energy and matter, our understanding of how energy metabolism works in ...

In Vivo Monitoring of Energy Metabolism with Genetically Encoded Fluorescent Biosensors - www.annualreviews.org/content/jour...

Agro-Hub is about to start!
🌱
Looking forward to two days of good science performed by our Andalusian PhD students!
@ihsmumacsic.bsky.social @ibvf-sevilla.bsky.social @csicdivulga.bsky.social @iascsic.bsky.social @eezcsic.bsky.social @irnase.bsky.social @csicandalextrem.bsky.social

Investigadores de seis centros del CSIC en Andalucía asistirán al tercer Agro-Hub Students Meeting el 12 y 13 en Sevilla El Instituto de Bioquímica Vegetal y Fotosíntesis (IBVF) acogerá los días 12 y 13 de marzo de 2026 la...

Investigadores de seis centros del CSIC en Andalucía asistirán al tercer Agro-Hub Students Meeting el 12 y 13 en Sevilla www.europapress.es/andalucia/no...

This! 👇

Our researcher Rafa Morcillo is co-organizing the workshop “Scientific Communication in Practice” within the ROOT-BENEFIT COST Action.
📍Larissa, Greece | 📅4–6 March 2026.
Scientists, communicators & creatives join forces to create impactful science outreach materials.

Model for membrane trafficking in the immune response to powdery mildew fungi.

#TansleyInsight article: Plant immunity depends on endomembrane trafficking

📖 nph.onlinelibrary.wiley.com/doi/10.1111/...
by Thordal-Christensen et al.

@sohini-d.bsky.social #PlantScience

Cover of Microbiology Outlooks featuring an article by Dr Damien Meyer on integrating game dynamics with within-host evolution genomics.

Is virulence a fixed trait? This first commentary in Microbiology Outlooks considers why it may be better understood as a context-dependent evolutionary strategy. Discover the Open Access article: https://doi.org/10.1099/mout.0.00001

👩 En el #DiaInternacionalDeLaMujer #8M destacamos el talento, la dedicación y la aportación de todas las mujeres que trabajan en el #CSIC

🔬 Su compromiso es clave para impulsar una ciencia al servicio de la sociedad

Seguimos trabajando por un entorno más igualitario 👇

CSIC Igualdad – Un compromiso colectivo – CSIC | Aprende En una institución gubernamental como el CSIC, al igual que en toda la administración pública, la igualdad entre mujeres y hombres es más que un concepto ético o una aspiración social; la igualdad entre las personas es un pilar fundamental para que las instituciones funcionen adecuadamente y p...

Hoy, Día Internacional de la Mujer, el CSIC reafirma su compromiso con una ciencia más inclusiva y con la integración de la perspectiva de género en la investigación.

👉 Conoce el itinerario CSIC Igualdad:

Conmemoramos el Día Internacional de la Mujer destacando las voces y perspectivas de mujeres que lideran centros e institutos del CSIC en Andalucía, junto con las delegadas del CSIC en Andalucía y Extremadura, quienes comparten su visión, experiencia y compromiso con la ciencia y la igualdad

#8M