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Posts by Phoolwanti Rani

The phage nucleus synergizes with an anti-defense protein to resist bacterial immunity Morgan et al. show that a phage-encoded protein functions as an antitoxin to counter DarTG2-mediated phage defense. They further explore the interplay between this anti-defense protein, the phage nucleus replication compartment, which encloses chimallivirus genomes, and the DarTG2 phage defense system.

Excited to share the last installation of my PhD work. Worked with an all-star team on this one who really made this all come together beautifully. @ranidreamer.bsky.social @amardeeep.bsky.social @benadler.bsky.social and many others. www.cell.com/cell-reports...

1 week ago 19 9 3 1
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One of my favorite capture 🫶🏽🫰
Not sure if he is teasing me 🫣

5 months ago 1 0 0 0
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Teachers are the quiet architects of tender minds. Shaping thought is never simple, yet it is among the most profound of callings. I remember mirroring their gestures, their words, their ways— as… | P... Teachers are the quiet architects of tender minds. Shaping thought is never simple, yet it is among the most profound of callings. I remember mirroring their gestures, their words, their ways— as thou...

www.linkedin.com/posts/phoolw...

7 months ago 2 0 0 0
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urldefense.com/v3/__https:/...

Feeling happy ❤️😇

8 months ago 4 1 0 1
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Synteny-aware functional annotation of bacteriophage genomes with Phynteny Accurate genome annotation is fundamental to decoding viral diversity and understanding bacteriophage biology; yet, the majority of bacteriophage genes remain functionally uncharacterised. Bacteriopha...

🚨 New preprint 🚨

My phage annotation tool, Phynteny, finally has a preprint and a brand new version powered by a cool AI transformer architecture and protein language models! #phagesky

www.biorxiv.org/content/10.1...

8 months ago 85 42 2 1
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Global vaccination effort saved 2.5 million lives from SARS-CoV-2 Thanks to vaccinations against SARS-CoV-2 in the period 2020-2024 2.533 million deaths were prevented at global level, one death was avoided for every 5,400 doses of vaccine administered. The 82% of the lives saved by vaccines involved people vaccinated before...

Global vaccination effort saved 2.5 million lives from SARS-CoV-2
->News-Medical | #Vaccination #Coronavirus #Health | More info from EcoSearch

8 months ago 66 27 2 2
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Structure of the virulence-associated Neisseria meningitidis filamentous bacteriophage MDAphi

Out in @pnas.org

Congrats @janboehning.bsky.social @abultarafder.bsky.social Miles Graham @mathieucoureuil.bsky.social
@mrclmb.bsky.social @hopitalnecker.bsky.social

www.pnas.org/doi/10.1073/...

9 months ago 57 18 1 1
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American science to soon face its largest brain drain in history Over the first half of 2025, the USA has cut science as never before. This disaster for American science is a gift to the rest of the world.

As happened in Germany in the 1930s, we will see an exodus of America’s greatest minds to other countries as scientists flee attacks by this administration on research. This is “Trump’s gift” to the world. And it is a catastrophe for the United States. bigthink.com/starts-with-...

8 months ago 153 65 3 3

Cools story about bacterial crosstalk influencing disease relevant traits! 🧪

8 months ago 13 5 0 0
Global Talent Ireland - Research Ireland Global Talent Ireland aims to attract exceptional mid-career and established researchers from across the globe to Ireland. Researchers funded through this programme are required to transfer their rese...

Research Ireland, on behalf of @deptoffhed.bsky.social, have today launched Global Talent Ireland - a new initiative to attract exceptional mid-career and established researchers from across the globe to Ireland.

For more information visit:
www.researchireland.ie/funding/glob...

9 months ago 65 36 2 10
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Antimicrobial resistance in chronic lung infection: the road to resistance Background Antimicrobial resistance (AMR) is a growing global health crisis and is particularly relevant to people living with chronic lung diseases such as bronchiectasis, cystic fibrosis and chronic...

#amrsky #microsky

thorax.bmj.com/content/earl...

9 months ago 1 1 0 0
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🌍🧽 The Aquatic Symbiosis Project, @utehentschel.bsky.social and @sangerinstitute.bsky.social are cranking out high-quality genome assemblies at record speed—setting the stage to answer remarkable questions about marine symbioses. 🌊🧬
👉 Blog: bit.ly/3INcrOA
📸 2 Elephant ear sponge: B. Mueller

9 months ago 28 9 1 0
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We have a preprint for you

EHD2 forms rings on caveolae necks, in contrast to most EHDs forming helices. We determined its structure on membranes and show that N-term acts as a spacer

By Elena, Vasya @vasiliimikirtumov.bsky.social, Jeff &Oli Daumke www.biorxiv.org/content/10.1...

10 months ago 107 34 4 0

Our latest preprint on peroxisomal fatty-acid transport is live!!

@ohsunews.bsky.social #OHSU @uofcalifornia.bsky.social #UCSF

10 months ago 14 8 1 0
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Well getting into photography

9 months ago 1 0 0 0

Although I am incredibly sad to miss ASV this year, I am very excited to have Tiia Freeman present our ongoing work on alphavirus evolution in @harmitmalik.bsky.social lab! 🦠🦟🌡️🧬

9 months ago 16 5 1 0

Tiia is a superstar, and will be presenting not one, but two separate projects that are currently in the works. Make sure to check out her flash talk (W4-9) and posters (P1-28 and P21-1) on Tuesday. We welcome and appreciate your thoughts and feedback! #ASV2025

9 months ago 12 4 0 0
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Preprint: “Structural modeling reveals viral proteins that manipulate host immune signaling”

Using AI-guided structural modeling, we find new families of viral proteins that sequester or cleave host immune signaling molecules

Congrats Nitzan Tal!

www.biorxiv.org/content/10.1...

9 months ago 78 34 1 0
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Recycling an old twitter thread for #ASV2025:

Heading to #ASV2023. One of my favorite meetings in virology.

My new students asked me for some tips on how to approach the meeting, so I thought I’d share some thoughts on scientific networking

9 months ago 19 6 1 0

Excited to share that our latest story on Restrictor is out now in @genesdev.bsky.social!! Big thank you to my fellow co-first author Hanneke, Karen @adelmanlab.bsky.social and co-authors Nathalie and Allison!

9 months ago 31 12 1 0
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MRC Postdoctoral Research Scientists x 5 - MRC Laboratory of Medical Sciences Applications are now open for up to five postdoctoral positions in the area of developmental epigenetics.

Interested in developmental epigenetics? So are we! Apply now to join us for your postdoc!

Multiple positions across multiple groups @mrc-lms.bsky.social

Projects spanning germline demethylation, gene regulation, genome architecture in development & disease 👇👇

lms.mrc.ac.uk/work/vacanci...

9 months ago 45 38 0 2
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Genome shuffling enables quantitative trait locus mapping in Bacillus subtilis Genetic mapping is a powerful tool for eukaryotic genetics that has only been applied to bacteria in limited circumstances. Quantitative trait locus (QTL) mapping generally relies on sexual recombinat...

Genome shuffling enables quantitative trait locus mapping in Bacillus subtilis

www.biorxiv.org/content/10.1...

9 months ago 6 3 1 0