Further cements #danionella as a robust model to study neurobiology 💪 🧪

An algorithm underlying directional hearing in fish Veith et al. show how a fish—Danionella cerebrum—can reliably startle away from sound. It uses the relative phase between particle motion and pressure to infer the direction of sound. This sensorimoto...

How do fish localize sound without interaural cues? @johve.bsky.social et al. found a behavioral algorithm for directional hearing that predicts behavior from a pressure/motion phase comparison and accounts for how this relationship varies with distance. www.cell.com/current-biol...

Tiny, transparent, and now charted! Our brain atlas of adult Danionella cerebrum includes >200 annotated regions, 29 whole-brain in situs, and male/female reference volumes – openly available, versioned and extendable. Work by @nkadobyansky.bsky.social and team.
www.biorxiv.org/content/10.6...

First whole-brain recording of social sound processing in a vertebrate. Surprises start in the hindbrain; thalamus gates conspecific calls; male and female brains diverge downstream. Work by @joerghenninger.bsky.social, @mh123.bsky.social sky.social and team. www.biorxiv.org/content/10.6...

They watched my entire brain while I was listening to my friends' gossip. Research 🤷

Protocol for assessing visual stimulus discrimination in Danionella cerebrum and Danio rerio using habituation/dishabituation Here, we present a protocol to assess visual discrimination in fish, specifically Danionella cerebrum and Danio rerio. We describe steps for the familiarization of subjects to reduce contextual novelt...

Our new paper is out
@mirkuz12
#zebrafish #danionella #number #numbersense
cell.com/star-protoco...

New morphometric analysis tool developed by Lu et al. applied to skeletal muscle cross-sections of four different juvenile teleost fish species. Main finding: Mosaic hyperplasia, i.e., the addition of new myofibers in the deep myotome, is near-zero in the small Danionella but dramatically enhanced in the giant danio relative to the intermediate grower zebrafish, establishing this mode of hyperplasia as a main driver of skeletal muscle growth in differently sized fishes.

Beautiful work led by Yansong (Kevin) Lu on skeletal muscle growth in zebrafish, giant danio, Danionella cerebrum, and killifish. HCR, new image analysis tool, scRNA-seq, and CRISPR. New international collaborations between Uni Melbourne, NCVC/Osaka, Stanford & ARMI www.biorxiv.org/content/10.6...

Whole-body Single-cell Spatial transcriptomic atlas of adult Danionella ~1 cm long

scRNAseq
MERFISH (500-gene)
HCR

Endothelial cell podxl+ (Fig S8)

Vascular vs Visceral mural cell (Fig S10)

Peter Reddien lab bioRxiv 2026
www.biorxiv.org/content/10.6...

Our latest study on the neurobiology of collective behavior is now posted as a preprint, led by UCSD PhD student Jo-Hsien Yu @anitajhyu.bsky.social @ucsandiego.bsky.social @danionella.bsky.social

www.biorxiv.org/content/10.1...

Oxytocin-mediated social preference and socially reinforced reward learning in the miniature fish Danionella cerebrum Penalva-Tena et al. demonstrate that Danionella cerebrum, a miniature fish that is gaining popularity as a neuroscience model, seeks out conspecifics and that the resulting social interactions can sup...

Out in Current Biology, by Ari Penalva and the Douglass lab: "Oxytocin-mediated social preference and socially reinforced reward learning in [☝️]":
www.cell.com/current-biol...
With a preview by Florian Engert:
www.cell.com/current-biol...

Danionella fishes - Nature Methods Miniature, transparent Danionella fishes, which are among the smallest living adult vertebrates, allow investigation of general principles of brain-wide neural circuits and evolutionary and developmen...

#Danionella in the creature column www.nature.com/articles/s41...

For today's #fluorescenceFriday, a transgenic Danionella cerebrum, the world's (second) smallest vertebrate (yep, "stout infantfish" are smaller, but no one has made them glow yet!). Picci by our very own @xinwei-wang.bsky.social

New work with @danionella.bsky.social from Naumann Lab @dukemedschool.bsky.social

Divergent Visuomotor Strategies in Teleosts: Neural Circuit Mechanisms in Zebrafish and Danionella cerebrum https://www.biorxiv.org/content/10.1101/2024.11.22.624938v1 Many animals respond to sensory cues with species-specific coordinated movements to successfully nav

Divergent Visuomotor Strategies in Teleosts: Neural Circuit Mechanisms in Zebrafish and Danionella cerebrum www.biorxiv.org/content/10.1101/2024.11....

I can't believe it!

do you accept distant cousins?

Switched waters to Bluesky. Still singing, still transparent, and back to having the smallest vertebrate brain around.