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Reactive microglia (🟠) and astrocytes (βšͺ️) as well as AΞ² plaques (πŸ”΅) in the hippocampal dentate gyrus of a 5xFAD mouse model of Alzheimer's disease.

#FluorescenceFriday

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Mouse brain stem section with GLP-1-producing neurons marked in green and low-activity neurons in magenta.

Mouse brain stem section with GLP-1-producing neurons marked in green and low-activity neurons in magenta.

This is a fun #FluorescenceFriday pic. My favorite NTS neurons that express a GLP-1 precursor in Green and the inverse activity marker phospho pyruvate dehydroxylase in magenta. Awesome work by my master's student Patience Otiya.

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#FluorescenceFriday
This microscopicπŸ”¬ object is a specialized immune cell (microglia) that resides in your retinaπŸ‘οΈ and is responsible for damage control and refinement of neural circuits. GFP labeled

@urneuroscience.bsky.social @urochestersmd.bsky.social @flaumeye.bsky.social @uofrbme.bsky.social

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Happy #FluorescenceFriday! Our #CellLineOfTheWeek is LAMP-1 - illuminating lysosomes. 🧫 ✨

Our stem cell lines & plasmids are available for just the cost of shipping to reduce the barriers to scientific discovery.

πŸ“¦ Hosted by @coriellinstitute.bsky.social & @addgene.bsky.social

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Happy #FluorescenceFriday! Today we are excited to share this video which shows a cleared mouse brain hemisphere following depletion of endogenous microglia and transplantation of human cells (magenta).

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The @mind-western.bsky.social #fluorescencefriday entry focus on the hippocampus of an aggressive AD model Appnl-g-f with IBA1 (yellow) and abeta (magenta). thanks to @shahrzadbahrampour.bsky.social @nadiahaghbinphd.bsky.social and @kesummers.bsky.social

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We had soooo much fun learning from Steve Farber this week. Please enjoy this zebrafish larval #FluorescenceFriday image with macrophages in red (the extensions!! 😍) and lipid uptake in the gut in green.

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microscopy images of a developing mouse spinal cord showing nuclei, actin, and membrane stains in rainbow coloring

microscopy images of a developing mouse spinal cord showing nuclei, actin, and membrane stains in rainbow coloring

Happy #FluorescenceFriday! This is a confocal πŸ”¬ series of a developing 🐭 spinal cord showing nuclei, actin, and cellular membrane stains colored in 🌈 Microscopy by postdoc @christinaadaly.bsky.social πŸ‘©β€πŸ”¬ πŸ§ͺ

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Such a beautiful example demonstrating the importance of developing and using robust biosensors
#FluorescenceFriday

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✨ Somite symmetry never fails to mesmerize 🐟
Trunk somites of a 1-day-old zebrafish embryo with nuclear (πŸ’™) and membrane (🧑) labelling πŸ“Έ Image credit: Matyas Bubna-Litic (Mongera lab, UCL) πŸ”¬ #FluorescenceFriday

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#Cilia are beautiful!

That's it, that's the tweet.

Oh, and Happy #FluorescenceFriday πŸ”¬

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A dark-blue background with bright red/yellow neurons arranged in a diagonal band through the middle. The right side is faintly striped, typical of the striatum.

A dark-blue background with bright red/yellow neurons arranged in a diagonal band through the middle. The right side is faintly striped, typical of the striatum.

Happy #FluorescenceFriday! Since I got to do some rare patching this week, enjoy this sagittal brain slice with ChAT+ interneurons in the Striatum, labelled in pAce-mNeonGreen.

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This #FluorescenceFriday post is for those who do 2-photon calcium imaging. Make your videos pop! @filip-tomaska.bsky.social released code and a demo to make the neural activity in your videos clear.
Code: github.com/ftomaska/roi...
Video demo: youtu.be/my1CE9sn2FQ

E.g.: bsky.app/profile/spen...

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Fluorescence Friday - Massage edition ! 🀏

By @pierre-bercier.bsky.social

#CellBiology #Microscopy #Nucleus #FluorescenceFriday
@crg.eu @prbb.org

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I can make my own flowers. πŸ’

Even in the lab. πŸ‘©πŸ»β€πŸ”¬

🀍πŸ§ͺ

#FluorescenceFriday #WomenInScience #LabLifeΒ #WomenInSTEM #ScienceCommunicationΒ Β #ResearchLife #SciencePhotography #flowers

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πŸ¦‚The haunting scorpion fluorescence! πŸ¦‚
The scorpions are embedded in resin. Fluorescence is produced with ultraviolet light, but most wavelengths produce fluorescence. We use them to test animal and wide-field fluorescence imagers.

#FluorescenceFriday #SciComm #SciArt #BioArt

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Featured image with Nat Prunet - FocalPlane Featured image with Nat Prunet - News

We are delighted to share this week’s featured image from Nat Prunet @nat-prunet.bsky.social, showcasing pollen grains from various plant species. Read our post to discover more about the image and learn about Nat’s research.

#FluorescenceFriday

focalplane.biologists.com/2026/03/27/f...

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For #FluorescenceFriday: an image that didn’t make the final paper. A dopaminergic, anaxonic OB neuron with dendritic release sites in magenta. Gephyrin in orange; TH in cyan confirms the GFP-labelled cell’s identity.

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πŸ₯š Egg hunt but make it neuroscience & microscopy for #FluorescenceFriday !πŸ’

With Easter around the corner, I'm sharing some of my latest imaging & sciart work: mouse olfactory bulbs made to look like beautiful FabergΓ© eggs! πŸ‘‘

The images were taken from 3D datasets of whole cleared mouse brains.

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Single molecular fluorescence in situ hybridization to outline white matter tracts (green, labeling MBP) and serotonin neurons marked in purple with TPH2

Single molecular fluorescence in situ hybridization to outline white matter tracts (green, labeling MBP) and serotonin neurons marked in purple with TPH2

Early for #FluorescenceFriday, but got an early peek in a project meeting - strucure is just so incredible - zoom in of tryptophan hydroxylase 2 labeling 🟣 of serotonin neurons in the dorsal raphe of human 🧠. Experiment and image credit to @ishbeldelrosario.bsky.social @svitlanabach.bsky.social

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Some work life impressions of the week:

Huge-a&& KIT logo downtown, our new slogan #scienceforimpact (I like it)

Friday evening Campus North institute sunset panorama

Drosophila testes imaging for revisions with @erhardtlab.bsky.social lab, samples looking great! #FluorescenceFriday #latergram

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Repost for #FluorescenceFriday and more #Hype4Hydrozoa

🟑 = developing or newly matured stinging cells in tentacles of a feeding polyp from a colony of β€˜hermit crab fur’ or Hydractinia symbiolongicarpus

πŸ§ͺπŸͺΌπŸ§ͺ

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micrograph of a section of neonatal mouse lung tissue showing cilia in yellow and nuclei in blue.

micrograph of a section of neonatal mouse lung tissue showing cilia in yellow and nuclei in blue.

Happy #FluorescenceFriday! Here is a micrograph of a section of a neonatal 🐭🫁 showing showing cilia in 🟑 and nuclei in πŸ”΅. Cilia are marked by the protein Arl13b. πŸ”¬ by postdoctoral fellow Sam Hack πŸ‘©β€πŸ”¬ πŸ§ͺ

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A movie from 9 years ago and I've never noticed the actin wave inside these cells until now 😱 It looks like a cluster of actin filament moving from 1 place to the other and pushing the cell membrane out to form protrusions. Reminds me of an ocean undercurrent. How interesting! #FluorescenceFriday

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For today’s #FluorescenceFriday, the #rods clearly chose chaos
What you’re looking at are long, beautifully coiled outer segments of rod #photoreceptors… basically the retina showing off its inner spaghetti aesthetic.
Elegant, tangled, and absolutely essential for seeing in low light.

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#FluorescenceFriday

This is beautiful by the way πŸ€©πŸ”¬

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A vivid #solvatochromism study of new two-photon absorbing chromophore by Meryem where it displays different colours in different solvents under UV #irradiation, as solvent #polarity influences its electronic states.😍😍 #fluorescencefriday @standrewschem.bsky.social @standrewsosc.bsky.social

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Fluorescence microscopy image of a section of human brain tissue using in situ hybridization techniques to label molecular markers of nuclei in the thalamus with different colors (yellow, red, pink and blue dots)

Fluorescence microscopy image of a section of human brain tissue using in situ hybridization techniques to label molecular markers of nuclei in the thalamus with different colors (yellow, red, pink and blue dots)

Double posting for #FluorescenceFriday to give the human 🧠 some face time - thalamus! How well molecular expression defines the anatomy of the sub-nuclei is really just exquisite - we've had a lot of fun getting to explore this region! Image credit to RA Felix Siewe in @kr-maynard.bsky.social lab πŸ”¬πŸ§ͺ

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First #FluorescenceFriday post! Some islands in the human NAc 🏝️🧠. Forever fascinated with this really cool population. Shoutout to @svitlanabach.bsky.social for the incredible Visium-HD targeting!

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Fluorescence microscopy of a section of mouse brain tissue with neurons labeled in green and red based on projection target

Fluorescence microscopy of a section of mouse brain tissue with neurons labeled in green and red based on projection target

For #FluorescenceFriday πŸ§ πŸ”¬πŸ§ͺ - mPFC projection neurons heading to ventral tegmental area 🟒 or the locus coeruleus πŸ”΄. Processes on some of these GPF+ neurons are just AMAZING! Image credit to our Circuits team! @jorge-miranda.bsky.social @rehg-j.bsky.social and Daniel Olivares!

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