Excited to share some of my PhD work on ubiquitin www.biorxiv.org/content/10.1...!

Huge collaborative effort from many people

Check out the whole story here

Detecting Protein Higher-Order Structural Changes Using Kinase as a Phospho-Labeler We developed an approach to detect protein conformational changes on a proteome-wide scale by labeling proteins with phosphate groups through in vitro kinase reactions. This structural proteomics appr...

We utilized protein kinases to probe substrate protein structures. The phosphate groups enabled selective extraction of labeled sites.
Detecting Protein Higher-Order Structural Changes Using Kinase as a Phospho-Labeler www.biorxiv.org/content/10.1...

Mass-spectrometry-based proteomics: from single cells to clinical applications - Nature This Review summarizes advances in mass-spectrometry-based proteomics and explores the potential applications of these technologies in the clinic.

In our latest @Nature review with Tiannan Guo & Judith Steen, we explore how technological breakthroughs are revolutionizing MS-based proteomics: From enhanced sensitivity enabling single-cell analysis to high-throughput plasma proteomics & AI-based data interpretation
www.nature.com/articles/s41...

Release DIA-NN 2.0 · vdemichev/DiaNN We are excited to announce DIA-NN 2.0, the most significant milestone in the history of DIA-NN development. Key Breakthroughs Proteoform Confidence mode: DIA-NN 2.0 solves the long-standing chall...

DIA-NN 2.0 is released! We consider it the biggest step forward in the history of DIA-NN. On modern LC-MS almost all identifications are now peptidoform-confident, with major improvements e.g. for phospho. Some other cool things too: github.com/vdemichev/Di...

#teamMassSpec here is a starting pack in case you just moved over, or in case you've been absent for a while. This is #proteomics or #massspec related. The pack is not comprehensive but it's a start.

go.bsky.app/HH7kqEh

Here's a new list for early career researchers (=not had your own lab for ages) in proteomics.

Feel free to ask to be added or removed, I've tried to make a guess but could've got it wrong.

I think it's good to also have an ECR network.

#teamMassSpec

go.bsky.app/Dp8PHX1