Switchable RNA motifs for dynamic transcriptional control of RNA condensates Abstract. RNA-driven phase separation is emerging as a promising approach for engineering biomolecular condensates with diverse functionalities. Condensate

We demonstrated how to make and dissolve #RNA #condensates through strand displacement using synthetic genes - excited to see this new paper out in @narjournal.bsky.social Collab w/ the Andersen group @esandersen.bsky.social academic.oup.com/nar/article/...

PyFuRNAce: An integrated design engine for RNA origami To realize the full potential of RNA nanotechnology and RNA origami, user-friendly design tools are needed. Here, we present pyFuRNAce, an open-source, Python-based software package with a graphical u...

Hey #RNA world, we are excited to share our RNA design engine #pyFuRNAce - an integrated tool for RNA origami experts and novices alike. Kudos to @monari-luca.bsky.social @floppleton.bsky.social et al! Preprint: www.biorxiv.org/content/10.1... Try it out at pyfurnace.de Feedback welcome!

Genetic encoding and expression of RNA origami cytoskeletons in synthetic cells - Nature Nanotechnology This study introduces RNA origami nanotubes as self-assembling cytoskeleton mimics for synthetic cells. Expressed in vesicles from DNA templates, these RNA structures reach micrometre lengths, deform ...

The Goepfrich lab @kgoepfrich.bsky.social yesterday published the creation of cytoskeleton-like structures with different properties inside lipid vesicles using RNA origami: www.nature.com/articles/s41...

The Cryo-EM: the next 50 years Symposium held yesterday at @ucberkeleyofficial.bsky.social was a smashing success!!

Foundations of Nanoscience

Abstract submission for FNANO is now open! They’re due Feb 1! Join us at molecular programming’s annual celebration of design, interfaces and applications (and also skiing) 🧬

www.fnano.org

We discovered 3 RNA families that form homo-oligomeric RNA-only complexes! Studying nature continues to expand my wildest imagination. Read about it: doi.org/10.1101/2024...
Vivian Wu, Svetlana Shabalina, Hyunbin Lee, Grace Nye, Eugene Koonin, Alex Gao, Rhiju Das, Wah Chiu

Amazing molecular animations with engaging soundscape!

Last year we met with about 60 scientists for 2 weeks to discuss what it means to synthesize life. Here is the summary of our discussion: chemrxiv.org/engage/chemrxiv/article-... We hope it represents diverse views and serves as a roadmap towards...

RNA’s Extreme Makeover - Lasker Foundation One day in November 2000, developmental biologist Victor Ambros sat down in his office at Dartmouth Medical School to read the latest issue of the journal Nature. Flipping through the pages, he was su...

Nice write up of the RNA revolution laskerfoundation.org/rnas-extreme...

Here is a starter pack for CryoEM/ET enthousiasts
To be completed
go.bsky.app/JmQksC

I would like to be added. Work on Cryo EM/ET of RNA.

To accelerate the X-odus, I created a DNA & RNA nanotech starter pack :) Comment if you want to be added!
go.bsky.app/7LUeJ61

I would like to join