In 2024, researchers working with the Realizing Increased Photosynthetic Efficiency (RIPE) initiative reported that the engineered potatoes grew 7.5–30% better than wild-type counterparts. Image credit: RIPE Project/Claire Benjamin (photographer), licensed under CC BY 4.0.

Wary of #ClimateChange impacts, researchers are boosting #CropResilience but must account for crucial #PlantBiology tradeoffs that affect #productivity and #nutrition. A PNAS News Feature: https://ow.ly/u47i50YAFGY

#soybeans #wheat #HeatWave #photosynthesis #condensates

An intrinsically disordered tug of war that fine-tunes acetylation Acetylation of histones and transcriptional regulators modulates gene expression, but how acetyltransferases define target specificity remains puzzling. In Cell Reports, Gelder et al. have shown how i...

Massive thanks to @jhenninger.bsky.social for the thoughtful preview of @katiegelder.bsky.social's recent story on CBP-IDRs. It’s fantastic to see her findings situated in the broader context of one of biology’s most dynamic fields* #IDRs #transcription #condensates www.cell.com/cell-reports...

Glad to share our new @cp-trendscellbio.bsky.social article! We discuss how repair condensates and lipid domains work together to restore lysosome integrity or deciding if it's time for lysophagy. #Lysosomes #Condensates #DamageSignature #Lipids #Ions Check it out: doi.org/10.1016/j.tc...

Combine harvester moving through a golden wheat field during harvest, with dust rising behind it under an open sky. Image credit: Shutterstock/Fotokostic.

Intent on climate-proofing #plants, researchers are boosting #CropResilience while accounting for crucial #PlantBiology tradeoffs that affect #productivity and #nutrition. A PNAS News Feature: https://ow.ly/rafJ50Ywr8I

#ClimateChange #soybeans #wheat #HeatWave #photosynthesis #condensates

CD-CODE v2.2 RELEASE is live🤩

Our #database grew:
💡10 new #condensates
💡639 new #condensate - #protein connections
💡107 new c-mods
💡10 new #condensatopathies

🟣Find your favorite condensate cd-code.org and 👀see more details about the #release: cd-code.org/release

#cdcode #IDP #RBP #DatabaseUpdate

Our TDP-43-paraspeckle paper is now published in Nature Cell Biology! 🎉

www.nature.com/articles/s41...

A Nature Research Briefing on this study will follow shortly.

Congratulations to joint first authors Rachel, Cara and Ruaridh👍

#paraspeckle #condensates #TDP-43 #ALS

Redirecting

Really pleased to share the *final* version of @katiegelder.bsky.social's super work, profiling the functional roles of #IDRs in CBP. Published today 🎉

🔗https://doi.org/10.1016/j.celrep.2026.117109

#IDRs #condensates #transcription #CBP #generegulation #enhancers (1/7)

Thanks for having me @danbose.bsky.social, I had such a wonderful time! Lots of cool questions & great to hear about the exciting research on #condensates and #generegulation @sheffielduni.bsky.social!

Fantastic to welcome @fariatrypslab.bsky.social for our @mcb-sheffield.bsky.social seminar today. So much cool work on #condensates and #generegulation, and can't get over how awesome #trypanosomes are!

Membrane-protein-mediated phase separation orchestrates organelle contact sites Hoffmann, Nagao, et al. show that PDZD8, an endoplasmic reticulum (ER) membrane contact site protein, forms liquid-like condensates through its intrinsically disordered region. These condensates media...

What if organelles where glued together by #condensates ?

The whole workshop has been well organised and super interesting, I have taken a lot of inspiration away from the talks so far and I am excited to for the rest of the day/week. (2/3) #MembraneTrafficking #Organelles #Mechanobiology #Condensates

How does molecular valency shape condensate assembly and function? We used the CO2-fixing organelle in algae—the pyrenoid—to find out… 🧵

Preprint here!:
www.biorxiv.org/content/10.6...

@cellarchlab.com @phaips.vd.st @biologyatyork.bsky.social
#Rubisco #PhaseSeparation #Condensates #Pyrenoid

We’re hiring a PDRA and a technician!
If you’re passionate about #parasites #genomes #condensates then this project is for you! Help us decode the role of nuclear architecture in gene expression regulation in #Leishmania alongside the @mottramlab.bsky.social @york.ac.uk @ybri-uoy.bsky.social

Seriously some of the most fun I’ve had in this field so far! 🥳🥳 #kitp #roadmap #condensates

Really valuable #preprint on biological #condensates, with some welcome terminological clarity:“Some papers equate condensates with #LLPS, but it is often neither clear whether the involved objects have liquid-like properties…nor whether they actually form by phase separation.”👏👇

📰Check out our series of Issues thematically aligned with the expertise of our academic editors

Explore the 'In the Limelight' series
🔦https://buff.ly/4b4aRkm

#AlzheimersDisease #RNAbiology #Glycosphingolipids #Neurotransmitter #Antivirals #Lysosomes #Condensates #Bioplastics

Original post on mastodon.social

"These results have broad implications for biological processes regulated by membrane potential, particularly in contexts such as neuronal signaling, where condensate interactions with membranes may play a previously unrecognized regulatory role."

#neuron #condensates #cellMembrane […]

2025-12-08: “Drugging Condensates & Drug Discovery” Dewpoint workshop – ComeInCell

Next Monday, 8 Dec at 2 pm CET (Berlin time), join a 2h online lecture on drug development involving biomolecular #condensates by Dr. Diana Mitrea (Dewpoint Therapeutics) & organized by @comeincell.bsky.social

🔗 info & registration:
tinyurl.com/3xsd9tmu

Events (Jul – Dec 2025) – ComeInCell

Monday blues no more with these online events by @comeincell.bsky.social (coordination: @dimovalab.bsky.social)

· 8 Dec, 2pm CET: “Drugging #Condensates & Drug Discovery” Dewpoint workshop

· 15 Dec 2pm CET: “Life in #Biotech” Dewpoint workshop

tinyurl.com/39rpaf84
#CellBiology #Biophysics

🌟G&D SPOTLIGHT 🌟

REVIEW: RNA granules: functional compartments or incidental condensates?
By Andrea Putnam, Laura Thomas and Geraldine Seydoux
➡️ https://genesdev.cshlp.org/content/37/9-10/354.abstract

#RNAmetabolism #RNAgranules #phaseseparation #RiboNucleoProteins #condensates

Hierarchical interactions between nucleolar and heterochromatin condensates are mediated by a dual-affinity protein - Nature Cell Biology Rajshekar et al. show that a hierarchy of affinities layers pericentromeric heterochromatin around nucleoli, with the RNA helicase Pitchoune (DDX18) acting as a key dual-affinity linker in Drosophila ...

Hierarchical interactions between nucleolar and heterochromatin condensates are mediated by a dual-affinity protein #condensates #chromatin
www.nature.com/articles/s41...

puzzle pieces are connected to represent CD-CODE database concept. landscape orientation (4 puzzle pieces top row, 5 puzzle pieces lower row). Top row: puzzles representing applicability, API, infectious condensate with logo representing pathogen cell and condensate, condensatopathies with a stethoscope logo, text: CD-CODE CrowDSourcing Condensate Database and Encyclopedia. Bottom tow: puzzles representing community, CD-CODE logo, Biomolecualr condensates with logos for species (human, frog, mouse), c-mods with chemical compound logo, DNA, proteins, RNA minimalistic logos.

CD-CODE 2.0 is now published in @narjournal.bsky.social 🤩
CD-CODE 2.0 stores #biomolecular #condensates and their #protein and nucleic acid components and now includes repository of 🦠 infectious condensates, 💊 condensate-modulating compounds, and 🩺 condensatopathies
👀 doi.org/10.1093/nar/...

Nanoscale domains govern local diffusion and ageing within fused-in-sarcoma condensates - Nature Nanotechnology Single-molecule tracking reveals nanoscale domains within fused-in-sarcoma condensates. These nanodomains migrate to the condensate surface during ageing, seeding amyotrophic lateral sclerosis-linked ...

New paper: Nanoscale domains govern local diffusion and ageing within fused-in-sarcoma condensates

Single-molecule tracking reveals nanoscale domains within #FUS #condensates that migrate to the condensate surface during ageing, seeding #ALS fibrils.

www.nature.com/articles/s41...

Many thanks #AntonioCostaFilho for the kind invitation to participate in the pre-meeting #SBBf course “Phase separation at membrane interphases: Biomolecular condensates in Actions”. Happy share session with #RumianaDimova #Condensates #LLPS #Bioimaging #Phasors #DANprobes

So proud of Chris Ng who successfully defended his PhD thesis recently!! Thank you to his examiners Alex Borodavka & Paolo Arosio. It’s been such a fun journey and we wish Chris great success with his new job ❤️ @lauraitzhaki.bsky.social @phar.cam.ac.uk #biomolecular #condensates

@science.org ATP-dependent remodeling of #chromatin #condensates reveals distinct #mesoscale outcomes | Science www.science.org/doi/10.1126/...

Attention colleagues! Interested in an interdisciplinary #PhD? 🧬 Apply now for one of 12 PhD positions exploring biomolecular #condensates! This program involves several PoL PIs, bridging the gap between physics and biology.

Apply here: dresdencondensates.org/join-us/
🗓Deadline: 24. October

🤩 We are delighted that Sheena Mali has joined #ComeInCell! She will be working in Di Michele’s lab in the UK. Her project will focus on engineering interactions between #syntheticRNA #condensates and #cellmembranes. More details: www.comeincell.org/dc17-sculpti...

Welcome, Sheena! #HorizonEurope

Check out our latest, where we investigate the molecular origin of differences between Lys and Arg and their roles in biomolecular #condensates

@dipcehu.bsky.social

www.biorxiv.org/content/10.1...

Visualizing nuclear structures often recognizable in electronmicroscopy imaging for chromatin. Nice.
@danfengcai.bsky.social #bodies #nucleus #dynamic #condensates #geneexpression www.biorxiv.org/content/10.1...