RESEARCH COMMUNICATION: Chromatin architecture reprogramming reveals novel epigenetic dependencies in breast cancer
By Garcia-Martinez et al. and Lluis Morey
➡️ https://genesdev.cshlp.org/content/40/7-8/429.full

Lluis Morey
#chromatin #transcription #breastcancer #histone

Как устроена транскрипция в Jitsi Meet: Jigasi, SIP и путь до EMR Когда мы проектировали пайплайн автоматического запо...

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Origin | Interest | Match

A H3K27me3 reader complex couples H3K27me3 accumulation to nascent transcription of transposable elements in Paramecium - Genome Biology Background The ability to deposit histone H3K27-trimethyl (me3) marks is essential for transcriptional repression by Polycomb Repressive Complex 2 (PRC2). This is largely attributed to Polycomb repres...

Our latest publication is now out at Genome Biology!
link.springer.com/article/10.1...

We uncover a unique association between a H3K27me3 reader complex and active transcription.
A thread with our key findings: (1/8)

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Transcription by Ben Lerner review – a stunning exploration of technology and storytelling Ranging from quantum mechanics to eating disorders to the nature of fiction, this is a breathtaking interrogation of family, connection and memory

Transcription by Ben Lerner review – a stunning exploration of technology and storytelling www.theguardian.com/books/2026/m...

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Ethylene Signaling Enhances Mitochondrial Stress Tolerance Independently of the Transcription factor ANAC017 in Arabidopsis Abstract. Mitochondria are central to plant metabolism, yet the diversity of mechanisms plants use to cope with mitochondrial stress and its implications i

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academic.oup.com/jxb/advance-...

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www.biorxiv.org/content/10.6...

Ancestry snip for Richard Dixon showing 1861 England Census has his birth transcribed as 1796 Napoehenter, Kent, England and the 1871 it is now Wapckester.

Didn't realise Napchester was such a tricky word ......
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An intrinsically disordered tug of war that fine-tunes acetylation Acetylation of histones and transcriptional regulators modulates gene expression, but how acetyltransferases define target specificity remains puzzling. In Cell Reports, Gelder et al. have shown how i...

Massive thanks to @jhenninger.bsky.social for the thoughtful preview of @katiegelder.bsky.social's recent story on CBP-IDRs. It’s fantastic to see her findings situated in the broader context of one of biology’s most dynamic fields* #IDRs #transcription #condensates www.cell.com/cell-reports...

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RESEARCH PAPER: Exosome-mediated decay of unstable long extended precursors of human telomerase RNA is dependent on 5′-cap trimethylation
By Samajdar et al. and Luis Batista
➡️ https://ow.ly/Ko1u50YyStI

Huntsman Cancer Institute
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RESEARCH COMMUNICATION: Chromatin architecture reprogramming reveals novel epigenetic dependencies in breast cancer
By Garcia-Martinez et al. and Lluis Morey
➡️ genesdev.cshlp.org/content/early/2025/12/18...

Lluis Morey
#chromatin #transcription

Species phylogeny, genomic and transcriptomic data, and Ne proxies used in the present study. Left: Phylogenetic tree of the 100 metazoan species considered. Middle: Available genome and transcriptome datasets of each species concerned, including CAGE-seq, 3′-end-seq, RNA-seq, coding genes, and BUSCO genes. Right: Ne and proxies.

What is the evolutionary significance of alternative #transcription initiation, #splicing & #polyadenylation? This study of 75 metazoan species suggests that most transcript diversity reflects deleterious RNA processing errors rather than adaptive function @plosbiology.org 🧪 plos.io/3Pcs2e6

Species phylogeny, genomic and transcriptomic data, and Ne proxies used in the present study. Left: Phylogenetic tree of the 100 metazoan species considered. Middle: Available genome and transcriptome datasets of each species concerned, including CAGE-seq, 3′-end-seq, RNA-seq, coding genes, and BUSCO genes. Right: Ne and proxies.

What is the evolutionary significance of alternative #transcription initiation, #splicing & #polyadenylation? This study of 75 metazoan species suggests that most transcript diversity reflects deleterious RNA processing errors rather than adaptive function @plosbiology.org 🧪 plos.io/3Pcs2e6

Species phylogeny, genomic and transcriptomic data, and Ne proxies used in the present study. Left: Phylogenetic tree of the 100 metazoan species considered. Middle: Available genome and transcriptome datasets of each species concerned, including CAGE-seq, 3′-end-seq, RNA-seq, coding genes, and BUSCO genes. Right: Ne and proxies.

What is the evolutionary significance of alternative #transcription initiation, #splicing & #polyadenylation? This study of 75 metazoan species suggests that most transcript diversity reflects deleterious RNA processing errors rather than adaptive function @plosbiology.org 🧪 plos.io/3Pcs2e6