Massive thanks to @jhenninger.bsky.social for the thoughtful preview of @katiegelder.bsky.social's recent story on CBP-IDRs. It’s fantastic to see her findings situated in the broader context of one of biology’s most dynamic fields* #IDRs #transcription #condensates www.cell.com/cell-reports...
Glad to share our new @cp-trendscellbio.bsky.social article! We discuss how repair condensates and lipid domains work together to restore lysosome integrity or deciding if it's time for lysophagy. #Lysosomes #Condensates #DamageSignature #Lipids #Ions Check it out: doi.org/10.1016/j.tc...
Combine harvester moving through a golden wheat field during harvest, with dust rising behind it under an open sky. Image credit: Shutterstock/Fotokostic.
Intent on climate-proofing #plants, researchers are boosting #CropResilience while accounting for crucial #PlantBiology tradeoffs that affect #productivity and #nutrition. A PNAS News Feature: https://ow.ly/rafJ50Ywr8I
#ClimateChange #soybeans #wheat #HeatWave #photosynthesis #condensates
CD-CODE v2.2 RELEASE is live🤩
Our #database grew:
💡10 new #condensates
💡639 new #condensate - #protein connections
💡107 new c-mods
💡10 new #condensatopathies
🟣Find your favorite condensate cd-code.org and 👀see more details about the #release: cd-code.org/release
#cdcode #IDP #RBP #DatabaseUpdate
Our TDP-43-paraspeckle paper is now published in Nature Cell Biology! 🎉
www.nature.com/articles/s41...
A Nature Research Briefing on this study will follow shortly.
Congratulations to joint first authors Rachel, Cara and Ruaridh👍
#paraspeckle #condensates #TDP-43 #ALS
Really pleased to share the *final* version of @katiegelder.bsky.social's super work, profiling the functional roles of #IDRs in CBP. Published today 🎉
🔗https://doi.org/10.1016/j.celrep.2026.117109
#IDRs #condensates #transcription #CBP #generegulation #enhancers (1/7)
Thanks for having me @danbose.bsky.social, I had such a wonderful time! Lots of cool questions & great to hear about the exciting research on #condensates and #generegulation @sheffielduni.bsky.social!
Fantastic to welcome @fariatrypslab.bsky.social for our @mcb-sheffield.bsky.social seminar today. So much cool work on #condensates and #generegulation, and can't get over how awesome #trypanosomes are!
The whole workshop has been well organised and super interesting, I have taken a lot of inspiration away from the talks so far and I am excited to for the rest of the day/week. (2/3) #MembraneTrafficking #Organelles #Mechanobiology #Condensates
How does molecular valency shape condensate assembly and function? We used the CO2-fixing organelle in algae—the pyrenoid—to find out… 🧵
Preprint here!:
www.biorxiv.org/content/10.6...
@cellarchlab.com @phaips.vd.st @biologyatyork.bsky.social
#Rubisco #PhaseSeparation #Condensates #Pyrenoid
We’re hiring a PDRA and a technician!
If you’re passionate about #parasites #genomes #condensates then this project is for you! Help us decode the role of nuclear architecture in gene expression regulation in #Leishmania alongside the @mottramlab.bsky.social @york.ac.uk @ybri-uoy.bsky.social
Seriously some of the most fun I’ve had in this field so far! 🥳🥳 #kitp #roadmap #condensates
Really valuable #preprint on biological #condensates, with some welcome terminological clarity:“Some papers equate condensates with #LLPS, but it is often neither clear whether the involved objects have liquid-like properties…nor whether they actually form by phase separation.”👏👇
📰Check out our series of Issues thematically aligned with the expertise of our academic editors
Explore the 'In the Limelight' series
🔦https://buff.ly/4b4aRkm
#AlzheimersDisease #RNAbiology #Glycosphingolipids #Neurotransmitter #Antivirals #Lysosomes #Condensates #Bioplastics
"These results have broad implications for biological processes regulated by membrane potential, particularly in contexts such as neuronal signaling, where condensate interactions with membranes may play a previously unrecognized regulatory role."
#neuron #condensates #cellMembrane […]
Next Monday, 8 Dec at 2 pm CET (Berlin time), join a 2h online lecture on drug development involving biomolecular #condensates by Dr. Diana Mitrea (Dewpoint Therapeutics) & organized by @comeincell.bsky.social
🔗 info & registration:
tinyurl.com/3xsd9tmu
Monday blues no more with these online events by @comeincell.bsky.social (coordination: @dimovalab.bsky.social)
· 8 Dec, 2pm CET: “Drugging #Condensates & Drug Discovery” Dewpoint workshop
· 15 Dec 2pm CET: “Life in #Biotech” Dewpoint workshop
tinyurl.com/39rpaf84
#CellBiology #Biophysics
🌟G&D SPOTLIGHT 🌟
REVIEW: RNA granules: functional compartments or incidental condensates?
By Andrea Putnam, Laura Thomas and Geraldine Seydoux
➡️ https://genesdev.cshlp.org/content/37/9-10/354.abstract
#RNAmetabolism #RNAgranules #phaseseparation #RiboNucleoProteins #condensates
Hierarchical interactions between nucleolar and heterochromatin condensates are mediated by a dual-affinity protein #condensates #chromatin
www.nature.com/articles/s41...
puzzle pieces are connected to represent CD-CODE database concept. landscape orientation (4 puzzle pieces top row, 5 puzzle pieces lower row). Top row: puzzles representing applicability, API, infectious condensate with logo representing pathogen cell and condensate, condensatopathies with a stethoscope logo, text: CD-CODE CrowDSourcing Condensate Database and Encyclopedia. Bottom tow: puzzles representing community, CD-CODE logo, Biomolecualr condensates with logos for species (human, frog, mouse), c-mods with chemical compound logo, DNA, proteins, RNA minimalistic logos.
CD-CODE 2.0 is now published in @narjournal.bsky.social 🤩
CD-CODE 2.0 stores #biomolecular #condensates and their #protein and nucleic acid components and now includes repository of 🦠 infectious condensates, 💊 condensate-modulating compounds, and 🩺 condensatopathies
👀 doi.org/10.1093/nar/...
New paper: Nanoscale domains govern local diffusion and ageing within fused-in-sarcoma condensates
Single-molecule tracking reveals nanoscale domains within #FUS #condensates that migrate to the condensate surface during ageing, seeding #ALS fibrils.
www.nature.com/articles/s41...
Many thanks #AntonioCostaFilho for the kind invitation to participate in the pre-meeting #SBBf course “Phase separation at membrane interphases: Biomolecular condensates in Actions”. Happy share session with #RumianaDimova #Condensates #LLPS #Bioimaging #Phasors #DANprobes
So proud of Chris Ng who successfully defended his PhD thesis recently!! Thank you to his examiners Alex Borodavka & Paolo Arosio. It’s been such a fun journey and we wish Chris great success with his new job ❤️ @lauraitzhaki.bsky.social @phar.cam.ac.uk #biomolecular #condensates
@science.org ATP-dependent remodeling of #chromatin #condensates reveals distinct #mesoscale outcomes | Science www.science.org/doi/10.1126/...
Attention colleagues! Interested in an interdisciplinary #PhD? 🧬 Apply now for one of 12 PhD positions exploring biomolecular #condensates! This program involves several PoL PIs, bridging the gap between physics and biology.
Apply here: dresdencondensates.org/join-us/
🗓Deadline: 24. October
🤩 We are delighted that Sheena Mali has joined #ComeInCell! She will be working in Di Michele’s lab in the UK. Her project will focus on engineering interactions between #syntheticRNA #condensates and #cellmembranes. More details: www.comeincell.org/dc17-sculpti...
Welcome, Sheena! #HorizonEurope
Check out our latest, where we investigate the molecular origin of differences between Lys and Arg and their roles in biomolecular #condensates
@dipcehu.bsky.social
www.biorxiv.org/content/10.1...
Visualizing nuclear structures often recognizable in electronmicroscopy imaging for chromatin. Nice.
@danfengcai.bsky.social #bodies #nucleus #dynamic #condensates #geneexpression www.biorxiv.org/content/10.1...
Come and hear about our latest story! It's a really nice series as well- sign up for the mailing list for updates #condensates #UKcondensates
