The more challenging targets CASP gets, the more the structural biology community will learn!

a cartoon of a man in a blue hat driving a vehicle ALT: a cartoon of a man in a blue hat driving a vehicle

#EvergreenTweet to journals: If you require me to make an account to decline a manuscript review, i'm not going to decline. I'm just going to delete your email. Following up with increasingly harassing emails for me to respond is going to put you on my journal blacklist

Will see how it goes on Friday. 🫣

“More natural”. A lot of stuff that is extremely natural is also extremely dangerous.

👀

There needs to be a giant billboard in every major American city that touts this. In any other era except this suicidal science administration, this would be a miraculous, wondrous thing.

Right? This thing, while cool, is not back-translating its own sequence (or another amino acid sequence). So, I do not see sequence information flowing in a way that is at odds with the central dogma. But maybe I am missing something…

The University of California system and California State system together enroll 770,000 students.

770,000

That's three quarters of a MILLION students in a PUBLIC education system that ranges in quality from good to world-class.

This is a miracle.

Dear funders, if you want to improve the success rate of your calls for scientific proposals, increase the budget instead of introducing new rules to try to reduce the number of applications.

With all the cuts to research funding in European countries, everyone is turning to the ERC...

The ERC should be a source of supplementary funding, not a substitute.

Every country in Europe must invest in basic research and increase its budgets!!!!

One of you good science people reposted this (presumably) without noticing that the thing in the background behind the moon is… also the moon. Please try not to amplify AI slop masquerading as science. Thx.

1/ Excited to share our preprint! 🥳

Degradation of aromatic compounds, including BTEX pollutants, requires highly endergonic aromatic ring reduction. Using #cryoEM and in situ #cryoET, we show how BCRII couples electron bifurcation modules in one giant redox machine

www.biorxiv.org/content/10.6...

This is why Russia is still fighting, why the war continues and why people are dying: Because Trump and Vance encouraged Putin to believe he could win

Very nice maps! Impressive! Did I read this correctly - this was done without even using @olibclarke.bsky.social's HR-HAIR approach?

Perhaps Magyar's most important promise, and the one that certainly resonates with voters: "never again a country without consequences!"

The crowd chants: "To prison! To prison!" [with the corrupt officials of the outgoing government]

The small protein cryo-EM paper I helped start has been accepted in Nature Communications - what a relief. Thanks to @landerlab.bsky.social and @olibclarke.bsky.social for their constructive review. Congratulations to all co-authors, and wishing everyone good luck.

www.nature.com/articles/s41...

Why Trump's approval won't go much below mid 30s as long as the Murdoch disinformation machine is allowed to act with impunity:
www.pewresearch.org/short-reads/...

Absolutely love the fact that (some) journals see a vector drawing of a protein complex in your paper and automatically assume you stole it from BioRender. 🙃

""I think people are sick of being told they can't have healthy rivers and seas, just because powerful financiers want to keep making money from our water bills.

"Our government is listening to them [water companies] but not to us,""

www.bbc.co.uk/news/article...

Live your life so that this is not the response to you losing your job.

“Science and antiscience are not the two sides of science” really voices what people don’t understand about why many of us have no wish to engage with MAHA.

Hungary election live: Polls in Hungary close in tightly fought election after 16 years under Viktor Orbán Prime minister has been trailing in the polls to Péter Magyar in race that could have repercussions for Europe, the US and Russia

GUARDIAN: "Viktor Orbán is now speaking at Fidesz’s election night and he says the election result is “clear” as he concedes defeat." www.theguardian.com/world/live/2...

👀

Not that I expect him to know this, but a blockade is an act of war

An armistice can take weeks to negotiate. A comprehensive peace treaty can take months. No one on Earth who knows a thing about history or diplomacy thought anything could be resolved in six hours. This will confirm for everyone the extreme incompetence and bad faith of the American regime.

Why tempted?

It is a bit insane that the Artemis II crew started from the earth, flew around the moon, and came back to the earth, faster than it takes for the journals to send your paper out for review.

Picture of hot cross buns.

Good. They do not call this a cross hot-bun, either.