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Posts by Jessica Little

Line graph showing the percentage distribution of Candida species from 2016 to 2024.
Candida albicans is the most common species in most years, declining from about 36% to 32%.
Candida glabrata increases overall, rising from about 25% in 2016 to a peak around 34% in 2024.
Candida parapsilosis fluctuates between roughly 8% and 17% before declining to about 8% by
2024. Candida tropicalis and unspecified/other species remain relatively stable at lower levels
(about 6–12%). Multiple-species infections decrease slightly over time. Candida auris is absent
before 2022 and then increases to about 5% by 2023–2024.

Line graph showing the percentage distribution of Candida species from 2016 to 2024. Candida albicans is the most common species in most years, declining from about 36% to 32%. Candida glabrata increases overall, rising from about 25% in 2016 to a peak around 34% in 2024. Candida parapsilosis fluctuates between roughly 8% and 17% before declining to about 8% by 2024. Candida tropicalis and unspecified/other species remain relatively stable at lower levels (about 6–12%). Multiple-species infections decrease slightly over time. Candida auris is absent before 2022 and then increases to about 5% by 2023–2024.

Candida glabrata emerges as the most common cause of candidemia: analysis of a large hospital-based database, United States, 2016–2024

academic.oup.com/cid/advance-...

Jeremy Gold & colleagues at CDC Mycotic Diseases Branch, @jessicalittlemd.bsky.social and @drluiso.bsky.social

1 week ago 31 16 4 1
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New webinar on fungal diagnostics!

Link in next post

3 months ago 2 4 2 0
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Controversial US study on hepatitis B vaccines in Africa is cancelled $1.6m project drew outrage over ethical questions about withholding vaccines proven to prevent disease

BREAKING: The controversial hepatitis B vaccine trial in Guinea-Bissau has been *cancelled,* I can now report. A senior official with Africa CDC confirmed the cancellation and said GB officials are working to make sure any research is conducted ethically:
www.theguardian.com/us-news/2026...

3 months ago 729 283 9 85

The full protocol of the study in Guinea Bissau provides no reassurance. If anything is spells out just how insanely unethical the planned study is. The PI who wrote the protocol tried to defend the indefensible by writing to me directly. I responded publicly.
Read 👇
substack.com/@bktitanji/n...

3 months ago 138 58 10 9
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Scoop: The leaked protocol of the CDC-funded Hepatitis B vaccine trial in Guinea-Bissau. “This is another Tuskegee.” The protocol reveals that the trial will withhold the Hepatitis B birth dose from thousands—without placebos, without universal maternal screening, and with endpoints critics call indefensible.

The leaked protocol of the CDC-funded Hepatitis B vaccine trial in Guinea-Bissau. “This is another Tuskegee.”

It is worse because it is clear upfront that this is unethical and poorly designed.
@insidemedicine.skystack.xyz

open.substack.com/pub/insideme...

3 months ago 4 1 0 1
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Invasive Fungal Disease in Transplantation: Prevention in a Shifting Landscape | Contagion Live Invasive fungal diseases remain a major cause of morbidity and mortality in patients undergoing transplant, with shifting epidemiology, emerging resistance, and geographic variation underscoring the u...

Quick read on #fungal infections in #transplant patients. @jessicalittlemd.bsky.social rocks! #IDSky #MedSky www.contagionlive.com/view/invasiv...

3 months ago 11 6 0 0
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Combination Therapy for Protracted COVID-19: When More is More

Combination Therapy for Protracted COVID-19: When More is More

✅ Just Accepted
#IDSky

9 months ago 4 2 1 0
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Protracted SARS-CoV-2 Infection in B-cell Depleted Patients: Immunologic and Viral Characteristics and Response to Dual and Extended Antiviral Therapy Immunocompromised patients remain at risk for protracted SARS-CoV-2 infections with persistent viral shedding that could pose a wider public health risk.

Protracted SARS-CoV-2 Infection in B-cell Depleted Patients: Immunologic and Viral Characteristics and Response to Dual and Extended Antiviral Therapy

✅ Just Accepted
⭐ Editor's Choice
#IDSky

9 months ago 4 4 0 0
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Advisory Committee on Immunization Practices at a Crossroads In this Viewpoint, former members of the Advisory Committee on Immunization Practices (ACIP) caution that the sudden change in the ACIP may reverse the achievements of US immunization policy, includin...

Important read from all 17 highly qualified ACIP members who recently dismissed - read and share widely

jamanetwork.com/journals/jam...

10 months ago 77 41 0 3
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Advisory Committee on Immunization Practices at a Crossroads In this Viewpoint, former members of the Advisory Committee on Immunization Practices (ACIP) caution that the sudden change in the ACIP may reverse the achievements of US immunization policy, includin...

Very proud of the 17 ACIP members for publishing this jamanetwork.com/journals/jam...

10 months ago 15 8 0 3
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One Hundred Days, Incalculable Losses Emily J Erbelding, M.D., M.P.H; One Hundred Days, Incalculable Losses, The Journal of Infectious Diseases, , jiaf317, https://doi.org/10.1093/infdis/jiaf31

"The story of the negative impact on the future of infectious disease research will only become part of public discourse if scientists speak up loudly"

A must read.

One Hundred Days, Incalculable Loses @jidjournal.bsky.social

Emily Erbelding, MD - NIAID/DMD

academic.oup.com/jid/advance-...

10 months ago 75 39 2 4
Leading Life Science Organizations: Unlawful Grant Terminations Pose Grave Threat to America’s Innovation Pipeline - ASCB Amicus Brief Filed in Support of Suit Calling for Immediate Funding Restoration WASHINGTON, DC – Four leading life science organizations, including the ASCB, filed an amicus brief today asking the cou...

Unlawful grant terminations are harming young scientists and threatening innovation. ASCB joins leaders calling for immediate funding restoration.

www.ascb.org/society-news...

11 months ago 143 71 2 7
Four Leading Science Organizations File Amicus Brief Supporting Funding Restoration ASM joined leading life science organizations in an amicus brief filed in support of a suit calling for immediate funding restoration.

Together with leading science organizations, ASM filed an amicus brief calling for immediate restoration of NIH grants supporting early-career scientists. Read the press release: asm.org/press-releas...

11 months ago 148 57 2 2

🚨UPDATE: Rümeysa Öztürk has now suffered three separate asthma attacks while in DHS custody.

She has not received her required asthma medications—a violation of her fundamental right to medical care.

This is cruelty, it is neglect, and it is a damning moral and legal failure.

1 year ago 13633 5798 224 238

ASH decries HHS restructuring and CDC layoffs. The Blood Disorders Division addresses SCD, thrombosis, hemophilia, thalassemia, and more. Millions' health is at stake; ASH urges immediate action.

#Fight4Hematology #HemeSky #MedSky

1 year ago 82 37 2 2
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'Bloodbath' at NIH and Elsewhere at HHS Begins Splinter is your home for news and opinions that challenge power in our political and economic system that's becoming more unhinged each and every day.

Today our nation's world leadership in science begins a slow death. We lose all the potential innovation, jobs, medicines, novel treatments, & science discoveries to save and improve lives. CDC & NIH will be a shell of themselves.

Will hurt for decades.

www.splinter.com/bloodbath-at...

1 year ago 2 3 0 0
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‘It’s a bloodbath’: Massive wave of job cuts began at US health agencies | CNN A massive wave of job cuts began at US health agencies early Tuesday, with some employees receiving early morning emails that their jobs were eliminated and some unable to access the building when the...

A sad day for science & public health www.cnn.com/2025/04/01/h...

1 year ago 68 27 0 3
SCiMaP

Just in NIH grants, It looks like beautiful Iowa City, home of the U of Iowa, will lose $71m in funding. That's almost $1k per resident. And that's before all the other cuts to SSA, FDA, etc.

Anyone in Iowa City that can offer more insight?
scienceimpacts.org
H/T to Prathima !

1 year ago 18918 5617 885 255
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We are committed to supporting #CancerCare providers and patients who may be affected by public health issues. A listing of measles and vaccination resources can be found on our website and will continue to be updated: asco.org/news-initiat...

1 year ago 13 10 0 0
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Some measles patients in West Texas show signs of vitamin A toxicity, doctors say, raising concerns about misinformation | CNN Doctors treating people hospitalized as part of a measles outbreak in Texas and New Mexico have also found themselves facing another problem: vitamin A toxicity.

Irresponsible public health leadership is dangerous and it kills.
The head of DHHS routinely tries to practice medicine without a license via podcasts and TV interviews and encouraged Vitamin A as treatment for measles. This is the direct result!
www.cnn.com/2025/03/26/h....

1 year ago 128 54 6 3

Sure looks like it'll be a 'study' with a predetermined outcome. If this were really an open question (it is not) it would make sense to contract with one of the numerous centers with extensive experience in vaccine trials. (1/2)

1 year ago 2 2 1 0
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Clinical Positions in Transplant Infectious Diseases 2024-2025 University of California, Los Angeles is hiring. Apply now!

We are hiring #TxID #TxIDSky faculty at @ucla-id-fellowship.bsky.social @domucla.bsky.social - come join our dynamic and collaborative group to battle infection in sunny Los Angeles! @ast-idcop.bsky.social See link for description and please reach out with questions! recruit.apo.ucla.edu/JPF09517

1 year ago 8 7 0 0
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New episode out now! Get to the bottom of a nonresponding pneumonia and hear some discussions about endemic fungal disease! 🍄 Ft. @tomschmidt30.bsky.social @natebahrid.bsky.social @grthompsonmd.bsky.social

Follow @msgerc.bsky.social for more fungal learning!
#IDSky

1 year ago 10 10 0 1
Febrile #115: Dust to Diagnosis – with MSGERC – febrile

Loved listening to this new @febrilepodcast.bsky.social episode on endemic mycoses 🍄with @grthompsonmd.bsky.social @tomschmidt30.bsky.social @natebahrid.bsky.social @msgerc.bsky.social

febrilepodcast.com/115-dust-to-...

1 year ago 5 2 0 0
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115: Dust to Diagnosis - with MSGERC Febrile · Episode

Check out the new episode of @febrilepodcast.bsky.social “Dust to Diagnosis”

Great experience working with @grthompsonmd.bsky.social, @natebahrid.bsky.social, & @msgerc.bsky.social!

open.spotify.com/episode/61sB...

#IDSky
#Fungi

1 year ago 15 10 2 0
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20250314-TTS-EC This is "20250314-TTS-EC" by TTS on Vimeo, the home for high quality videos and the people who love them.

Looking for a comprehensive review of measles in solid organ transplantation? #TTS #TID organized a webinar that will get your prepared! It is on 🔥 @kottonnelson.bsky.social @jobadd.bsky.social
urldefense.com/v3/__https:/...

1 year ago 15 7 0 0
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UMass Chan rescinds admission for biomedical sciences PhD program amid funding concerns UMass Chan Medical School is rescinding admission offers to candidates for its biomedical sciences PhD program over concerns about federal funding cuts.

A troubling moment for the next generation of scientists.

UMass Chan Med School is rescinding dozens of PhD offers in biomedical sciences due to fears over federal research funding cuts.

www.nbcboston.com/news/local/u...

1 year ago 467 196 18 19
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Measles virus infection diminishes preexisting antibodies that offer protection from other pathogens Measles virus infection can cause long-term damage to the immune system.

MMR is better than natural infection for many reasons > Measles virus infection diminishes preexisting antibodies that offer protection from other pathogens #measlesoutbreak www.science.org/doi/10.1126/...

1 year ago 11 4 0 0

Why…

1 year ago 7 5 0 0
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ID physicians stand up for science to protect our patients. #IDStandsUpForScience

In honor of tomorrow's #StandUpForScience rallies, share the reason why you stand up for science with the hashtag #IDStandsUpForScience.

1 year ago 39 12 0 1