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Posts by Sagar Bashyal

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Silencing of MiPSKs compromises gall formation in tomato plants and parasitic success

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All four MiPSK genes identified exhibited strong expression in root-attracted J2s compared with other developmental stages.

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Meloidgyne incognita was selected for further experimental analysis. In situ hybridization assay shows that MiPSK transcripts are expressed in the esophageal glands of nematodes

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PSK like proteins from PPN forms monophyletic clade

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Interestingly, some PSK motifs in nematode encoded proteins are identical to plant PSK ones. However, the variable domains aa are quite different from the plant ones.

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Happy to see this in biorxiv 🎉. Really proud of how it started and ended. Very first report of new peptide class “ PSK” encoded by parasitic nematodes. Nematodes getting smarter 🎉 Congrats to all authors
@nemaplant.bsky.social lab and @lmueller.bsky.social lab.

www.biorxiv.org/content/10.6...

2 weeks ago 14 5 1 0

🍅 Happy #TomatoTuesday from @nature.com Nature Genetics! #PlantScience 🍅

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it was great to collaborate with @lmueller.bsky.social to help characterize the Medicago crn mutant!

4 months ago 11 6 0 0
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Thank you @aribidopsis.bsky.social for this invitation and was a good open discussion. I really enjoyed it and hope to join more in future.

4 months ago 1 1 0 0
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SALICYLIC ACID SENSOR1 reveals the propagation of an SA hormone surge during plant pathogen advance Salicylic acid (SA) is a key phytohormone that orchestrates immune responses against pathogens, including Pseudomonas syringae bacteria. The timing and extent of SA accumulation are tightly controlled...

SALICYLIC ACID SENSOR1 reveals the propagation of an SA hormone surge during plant pathogen advance

www.science.org/doi/10.1126/...

6 months ago 5 2 0 0

Congratulations 🎉

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Grateful to be honored with the Alstroemeria Award from @ucsandiego.bsky.social
🌸. This recognition would not have been possible without the incredible support from so many people behind the scenes, thank you for lifting me up along the way. @salkinstitute.bsky.social

6 months ago 7 0 0 0
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Plant biologist Lucia Strader joins Salk faculty to study plant growth signaling - Salk Institute for Biological Studies LA JOLLA—The Salk Institute will welcome plant biologist Lucia Strader as a new professor and holder of the Howard H. and Maryam R. Newman Chair in Plant Biology in October 2025. Strader is an interna...

The lab is moving to the Salk Institute! We are thrilled to join an inspiring community where we will continue to explore plant growth and development.

Deep gratitude for the years of support and collaboration at Duke/NCSU/UNC.

www.salk.edu/news-release...

7 months ago 124 19 4 1
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Thrilled to have our spatial single-cell atlas of the Arabidopsis lifecycle in @NaturePlants. Turns out that its easy to make nice images when spatial expression of 1,000 genes is available! 1/n
@natanellae.bsky.social @tatsuyanobori.bsky.social @joeecker.bsky.social

www.nature.com/articles/s41...

8 months ago 70 41 7 4

Congratulations Travis 😊 Nice work🎉

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It’s one of the best feelings 🙃

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Congratulations Natalia 🎉

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I am thrilled to share the 2nd chapter of my PhD with @adsteinbrenner.bsky.social In collaboration with @tiszapatrick we demonstrated that the LRR-RLP INR is the missing molecular link between caterpillar recognition and predatory wasp recruitment in the field. A thread 1/6

8 months ago 33 17 2 1
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Unlocking expanded flagellin perception through rational receptor engineering - Nature Plants Receptor kinase FLS2 detects the flg22 epitope of bacterial flagellin. Here the authors identify key residues on FLS2’s concave surface that enable expanded perception of flg22 variants, allowing the ...

Excited this paper is finally published! We focused on the inner concave surface of LRR RKs to expand bacterial flagellin perception in plants. Selection indicates expanded perception is more common than previously thought. Experiments led by @jerrytli.bsky.social www.nature.com/articles/s41...

8 months ago 107 46 10 1
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Grateful to be at #2025ISMPMI! Reconnected with my former mentor @carogutj.bsky.social and met Maria, my current PIs mentor-so many cool stories🌱
Loved the energy at the poster session and great chats, including with Ertao Wang whose AMF work continues to inspire. #AMF

9 months ago 5 2 0 0
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Mark Estelle- UC San Diego- honored for his lifetime of excellence in research, mentorship, and support of the Arabidopsis community #ICAR2025

10 months ago 31 7 0 0
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The latest publication from our lab!

The famous "glomalin" from arbuscular mycorrhizal (AM) fungi is not a protein but a polysaccharide from AM fungi, so we renamed it "glomalose". Glomalin-related proteins are bacterial proteins stuck in this glomalose.
nph.onlinelibrary.wiley.com/doi/10.1111/...

10 months ago 73 40 3 0
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Exploring the untapped potential of single‐cell and spatial omics in plant biology Advances in single-cell and spatial omics technologies have revolutionised biology by revealing the diverse molecular states of individual cells and their spatial organization within tissues. The fie...

Excited to share my new Tansley Review @newphyt.bsky.social on emerging single-cell and spatial omics technologies, many of which are just beginning to be applied in plant biology! Big opportunities lie ahead for the field. [1/n] 

nph.onlinelibrary.wiley.com/doi/10.1111/...

11 months ago 107 61 3 1
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Plant Peptide Receptor Meeting 2025

Join us for the 🪴 🌵 Plant Peptide Receptor Meeting 2025 ☘️ 🪴 in 🏴󠁧󠁢󠁳󠁣󠁴󠁿 Edinburgh 🏴󠁧󠁢󠁳󠁣󠁴󠁿 8th-10th September

#plantsignaling #PlantScience #plantsci

pprm2025.events.kdmeventsportal.co.uk
@pprm2025.bsky.social

A thread 🧵
(1/n)

11 months ago 29 27 1 0
PNAS Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

Congratulations Michael and the entire team!👏Cool work from the @carogutj.bsky.social lab and a testament to all the long hard work behind it @pnas.org . Grateful to have contributed to this story✌️. Checkout the mechanisms by which the RAM1 functions.
www.pnas.org/doi/full/10....

11 months ago 4 1 0 0

Thank you☘️

11 months ago 2 0 0 0
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Our editors write:

- "Symbiosis signalling: Mycorrhizal CLE mimicry" rdcu.be/elQ6S

11 months ago 11 2 2 1
Mycorrhizal CLE mimicry - Nature Plants Nature Plants - Mycorrhizal CLE mimicry

Great to see our work highlighted in
@natplants.nature.com !🍀☘️🍄
Check it out: nature.com/articles/s41...
@lmueller.bsky.social @salkinstitute.bsky.social @ucsandiego.bsky.social

11 months ago 4 0 0 0

🌍 International Molecular Mycorrhiza Meeting 2025!
#IMMM2025
🏨 Book your hotel at our discounted group rate: genetik.bio.lmu.de/immm-2025/lo...
⚠️ Discounted rate only available until May 16th – act fast!

11 months ago 4 3 0 0
Signaling peptides control beneficial and pathogenic plant-microbe interactions Interactions between organisms, such as those between plants and microbes, require extensive signaling between and within each organism to detect and recognize the partner and elicit an appropriate response. Multiple families of small signaling peptides regulate plant interactions with beneficial or pathogenic microbes, and sometimes both. Some of these signaling peptides transmit information between different cells or organs of the host and allow plants to orchestrate a coordinated response towards microbial mutualists or pathogens. However, not only plants produce signaling peptides required for the interactions. Microbes themselves also secrete peptide signals, which are detected by host receptors and required for infection. Among these are microbial peptides mimicking those of plants, allowing mutualistic or pathogenic microbes to hijack endogenous plant signaling pathways and evade the host immune system. In this review, we provide a comprehensive summary of current knowledge on host- and microbe-derived signaling peptides and their cognate receptors regulating mutualistic and parasitic plant-microbe interactions. Furthermore, we describe how microbes hijack endogenous host signaling pathways, and discuss possible crosstalk between the plant signaling pathways controlling mutualism with those modulating immune responses to pathogens.

Great review from @lmueller.bsky.social -> Signaling peptides control beneficial and pathogenic plant-microbe interactions | Journal of Experimental Botany | Oxford Academic

11 months ago 11 6 0 0