Make your own PDMS+micromirror device for single-objective light-sheet SMLM: www.biorxiv.org/content/10.6...

It's funky axons time 🔬 🧪

say hello to Laurent! just started his PhD, and new on bluesky. cloning-wizzard and optogenetics-guru, using microscopy to link signaling & mechanics

📣 Submission deadline extended for special issue "Taking the Stage: The Future of Microscopy"!

The Journal of Microscopy has launched an open call for papers for an exciting new special issue which will feature submissions by Early Career Researchers.

Deadline extended: 30 April 2026

🚨📰Now online in its full form www.nature.com/articles/s41...

Hi all fans of #smart #microscopy,

we from @zeiss-microscopy.bsky.social have just published a new application note: "Study Mitotic Progression with Guided Acquisition – Rare Event Detection"

go2.zeiss.com/ODk2LVhNUy03...

For more details: forum.image.sc/t/applicatio...

happy to share via mail!

Smart microscopy for automation of optogenetic targeting YouTube video by miti rtmfm

Recording of talk for the french bioimaging network RTmfm. My PhD work in @olivierpertz.bsky.social lab (closed-loop optogenetics, microfabrication, image analysis w/ Convpaint). On smart microscopes: the issue of interoperability and some preliminary results on LLM control :) youtu.be/Gvaw2kWsVIk

Such an intriguing concept for the future of smart microscopy, especially appreciate how the paper builds on the foundations of knowledge creation, rather than arguing from a technolocial perspective first!

🔬 In this new open access paper, the authors introduce a theoretical framework that reconceptualises smart microscopy as a partner in scientific investigation.

Central to their framework is the concept of the ‘epistemic–empirical divide’ in cellular investigation, ...

Open Blink: Low-cost TIRF microscopy for super-resolutionimaging via μManager www.biorxiv.org/content/10.64898/2026.03...

Excited to see direct streaming of @openmicroscopy.org @zarr.dev datasets in #syGlass!

Exploring huge images without upfront download is just what we’ve been working toward with cloud-optimized formats.

Great to have tools connecting the ecosystem of imaging repositories, now including VR 🙌

napari 0.7.0 ⚠️ Note: these release notes are still in draft while 0.7.0 is in release candidate testing. ⚠️ Tue, Mar 10, 2026 We’re happy to announce the release of napari 0.7.0! napari is a fast, interactive,…

Check out and give feedback on the latest pre-release 0.7.0rc0! You can install with `pip install "napari[all]>=0.7.0rc0"` or via the bundled app. 😁 🥳

The release notes, with highlights, include so many great new features and changes: napari.org/dev/release/...

Tiny, transparent, and now charted! Our brain atlas of adult Danionella cerebrum includes >200 annotated regions, 29 whole-brain in situs, and male/female reference volumes – openly available, versioned and extendable. Work by @nkadobyansky.bsky.social and team.
www.biorxiv.org/content/10.6...

Calling for protocols on The Basics: get a protocol recorded and peer reviewed, and help a colleague learn the tips and tricks by *seeing how it's done*
You don't need to include new results and it does not have to be your original protocol. Just cite well and share the know-how 💕🔥

Get in touch!

napari needs your help! Has napari helped you make cool and groundbreaking discoveries? We'd love to highlight that in our docs. Please tell us about it! You can fill in this survey:

napari.typeform.com/to/vTCKeTKv

and/or, as ever, drop by our chat room or meetings:

napari.org/dev/community/

🙏

Smart microscopy for automation of optogenetic targeting YouTube video by miti rtmfm

Live in 1h! www.youtube.com/live/infTDml...

🚨Preprint! Happy to share the research from my PhD “Genome delivery of a contractile tailed phage and its superinfection exclusion mechanism”. We use cryoEM to study the genome ejection of the phage T4, revealing how the tape measure protein regulates the process.
www.biorxiv.org/content/10.6...

Leclech, C., Cardillo, G., Roellinger, B., Zhang, X., Frederick, J., Mamchaoui, K., Coirault, C., & Barakat, A. I. (2025). Micro-Scale Topography Triggers Dynamic 3D Nuclear Deformations. Advanced science, 12(11), e2410052. #EpithelialMechanics
doi.org/10.1002/advs...

A cochlea imaged in light-sheet microscopy (right) with staining for spiral ganglion neurons (red) and inner hair cells (blue). You will develop AI-based methods to analyze these structures, for example via segmentation of the individual cells (right) that will support gene therapy development for hearing loss and a better overall understanding of the anatomy of hearing.

Looking for a PhD position at the intersection of AI, imaging, and gene therapy? Apply for this position in my lab: tinyurl.com/2a2v6tvx

Part of sfb1690.uni-goettingen.de to study hearing, vision, and more.

Plus, you can create pretty pictures as the one below :).

Very happy that MuViT, our (CVPR 2026!) work on learning across spatial scales in microscopy w transformers, is out! Check Martin's thread for a nice walkthrough :)
Big thanks to my advisors @maweigert.bsky.social @gioelelamanno.bsky.social!
🖥️: github.com/weigertlab/muvit
📜: arxiv.org/abs/2602.24222

Excited to share our new paper (CVPR 2026 🚀): "MuViT: Multi-Resolution Vision Transformers for Learning Across Scales in Microscopy" which enables local predictions to use global context.
Great work led by @albertdm.bsky.social & another fun collab w @gioelelamanno.bsky.social! @scadsai.bsky.social

👏👏👏

mail to smwgadmin@eurobioimaging.eu :)

Go Lucien!! Love to see it

Feel welcome to add your smart microscopy project! smartmicroscopy.github.io/implementati... (mail/dm or PR on github). We also have a monthly online meeting on all things smart microscopy, all labs & companies welcome!

PAPER OUT ✨ How can we make smart microscopy more interoperable? What are the technical and cultural challenges? 30+ people from academia and industry propose a roadmap: doi.org/10.1515/mim-... Also a review of applications and repo of implementations. Join the discussion! smartmicroscopy.github.io

Our article on how to use micropatterned presynapses-on-glass is out in its final form in the latest issue of the Journal of Neuroscience @sfnjournals.bsky.social: www.jneurosci.org/content/46/8...
The cover went to the special section on social neuroscience, so here's our #notthecover attempt

Get in touch if you want to be paid to work with us this summer. We are particularly interested in hearing from scientists who are interested in software development!

GitHub - imaging-formats/bffile: Modern Bio-Formats wrapper with clean lazy Python API Modern Bio-Formats wrapper with clean lazy Python API - imaging-formats/bffile

Rewrote my Python bioformats wrapper (from aicsimageio/bioio) as a standalone package:

- fully bootstrapped Java setup (just pip install)
- lazy, repeatably-indexable Array object
- fully spec-compliant OME-Zarr group obj.
- xarray/dask exports

github.com/imaging-form...
v0.0.rc1 on PyPI