Happy #3DThursday from Sweden! 🇸🇪 This Thy-1 mouse brain was the crowd favorite at Focus on Microscopy this year 🐭
🔬: Zeiss Lightsheet Z.1
🥼: Chih-Wei Logan Hsu @cwloganhsu.bsky.social
🏛️: Baylor College of Medicine
🎬: syGlass, v2.6.0
#FOM2026 #syGlass #Microscopy @scilifelab.se
Fun #3DThursday update: #syGlass now supports the #Sony Spatial Reality Display! 🎉📺
Glasses-free 3D—no headset needed. Just walk up, look, and see depth instantly. A powerful new way to share scientific data with researchers, students, and the public.
#3DVisualization #SciComm #EdTech
☘️ A special #3DThursday for St Patrick's: Beer foam evolving in 4D in a microCT! 🍻
This is a Belgian Duvel (sorry not Irish...) from @tescan.bsky.social + Wesley De Boever
Who’s off to #FOM2026 in Stockholm? I'll be there next week!
www.focusonmicroscopy.org
#Microscopy #MicroCT #Imaging #syGlass
Excited to see direct streaming of @openmicroscopy.org @zarr.dev datasets in #syGlass!
Exploring huge images without upfront download is just what we’ve been working toward with cloud-optimized formats.
Great to have tools connecting the ecosystem of imaging repositories, now including VR 🙌
Streaming OME-Zarr data directly into syGlass for #3DThursday🌍🔬
With #syGlass v2.6.0, datasets can stream from disk, S3, or HTTPS with no massive downloads required.
Huge thanks to the community building open imaging standards:
@openmicroscopy.org
#OMEZarr #Microscopy #OpenScience #Bioimaging
The fruit fly of plant science for #3DThursday! 🌱 #ModelOrganism
🔬: #microCT, Zeiss @zeiss-microscopy.bsky.social Versa 520 XRM (contrast-enhanced with OsO₄)
🌱: Arabidopsis thaliana
🥼: Keith Duncan @cygnusplantxray.bsky.social
🏛️: Danforth Center @danforthcenter.bsky.social
🎬: syGlass.io #syGlass
Image credit: A male water flea (Daphnia magna): yellow 🟨 is musculature, magenta/gray 🟪 shows autofluorescence of its outer cuticle.
🔬: Fluorescence Microscopy
🥼: Carsten Wolff @carsten-wolff.bsky.social
🏛️: Marine Biological Laboratory @mblscience.bsky.social
📸: #syGlass
New in syGlass for #3DThursday: a VR surface brush for editing meshes🖌️Here, I’m isolating a component from a @lumafield.bsky.social #microCT scan of a VR headset, painting partitions directly onto the surface and exporting clean .OBJs: v2.6.0
#VR #3DVisualization #syGlass #ScientificVisualization
syGlass v2.6.0 is out for #3DThursday! ❄️
🖥️ Sony Spatial Reality Display support
☁️ Direct OME-Zarr streaming from disk, S3, or HTTPS
🖌️ VR surface partition brush
⌨️ In-VR keyboard & numpad
🎮 Saved tool loadouts
www.syglass.io/blog/syglass...
#syGlass #Bioimaging #VR #3DData #OMEZarr #Sony
❤️ A cleared guinea pig heart for #3DThursday! Clearing a heart is HARD — dense muscle, deep antibody labeling, big volume. But to understand coronary networks, you need the whole organ.
🔬: Miltenyi Ultramiscroscope
🥼: Pam Rios Coronado, @pamrc.bsky.social
🏛️: Red-Horse lab @stanford.edu
🎬: #syGlass
🌕 Exploring a 3.6-billion-yo moon rock for #3DThursday! Showing how we can virtually slice through the volume, inspect internal structures, and take 3D measurements from #XCT data.
🔬: #Nikon XTH320 Scanner
🥼: Zoë Wilbur
🏛️: #NASA JSC Astromaterials X-ray Computed Tomography Lab
🎬: #syGlass, v2.5.0
Running TotalSegmentator inside #syGlass for #3DThursday! 🔬 Automated segmentation needs strong clinical data for training and benchmarking, plus models that generalize. Mayo Clinic Low Dose CT Grand Challenge + #TotalSegmentator by Jakob Wasserthal are great examples.
#MedicalImaging #3DImaging
The Allen Mouse Brain Atlas is a cornerstone of #neuroscience: a standardized, high-resolution map of brain anatomy built to keep experiments comparable across labs. 🧠 Here’s a 3D walk through its anatomical meshes in #syGlass!
@alleninstitute.org
#3DThursday #DataViz #VR
🪰 For #3DThursday, this #microCT scan of an adult #Drosphila (Schoborg et al.) captures the entire fly intact. Using #VR, we can teach anatomy by labeling the 3D fly from a 2D diagram. Spatial context changes everything. #SciComm
🔬: Bruker SkyScan 1172
🏛️: UWyoming
🎬: #syGlass, v2.5.0
2025 took us around the world 🌍
From Zurich to Beijing, London, Paris, Montreal, all over the Americas, we explored scientific datasets in VR with the researchers who created them -- and pushed #syGlass to new limits for 3D analysis.
On to 2026. 🔬✨
#3DThursday #Microscopy #ScientificImaging
🎄 A canonical visualization dataset, revisited! This #CT Christmas tree (2001) became a classic for teaching & benchmarking volume rendering. I’ve brought it into #syGlass to explore how far #3Dvisualization has come — same data, new method. 🔬 #3DThursday
Story: www.cg.tuwien.ac.at/page/xmas/
Nice feature from NVIDIA on #syGlass at the MBL! Exciting to see AI, RTX GPUs, and VR coming together to explore massive 3D brain datasets, with high school students contributing to ongoing, cutting-edge neuroscience research.
@mblscience.bsky.social
blogs.nvidia.com/blog/mbl-hum...
Label-free #holotomography for #3DThursday! This imaging technique lets you follow the same living organoid in 4D with no dyes or phototoxicity.
🔬: @tomocube.bsky.social, HT-X1
🧫: Mouse Intestinal #Organoid
🏛️: Institut Pasteur Workshop, Pushing the Frontiers of Dynamic Imaging
🎬: #syGlass, v2.5.0
#syGlass v2.5.0 is out! 🎉
New depth-aware colormaps, expanded file formats (NRRD/MRC/TCF/OME-Zarr v3), better #VR segmentation tools, and upgraded narration workflows — all focused on making #3Ddata easier to explore and share.
Blog: www.syglass.io/blog/syglass...
#Microscopy #Imaging #3DThursday
Guest lectured at UNH–Manchester’s Techniques in Microscopy this week, and the students are already thinking like researchers. Early exposure to real #Microscopy and #ImageAnalysis tools makes all the difference.
🔬: Zeiss LSM 510
🥼: Students + Prof Mark Scimone
🎬: syGlass.io
#3DThursday #syGlass
One year of #3DThursday! Revisiting our first specimen, a Pekin duck: thanks to this community we learned she was Beaker, a rescued duck from Utah who later contributed to science.
🔬: #CTScan, Scarlet Imaging's BriteVu
🥼: Scott Echols
🎬: syGlass.io
🦆📸: credit TIFOtter
#Anatomy #syGlass #SciComm
Happy #MicroscopyMonday! This week we're spotlighting Brandy Freitas, our Director of Media and Outreach at #NESM.👏 @brandy-syglass.bsky.social
Brandy is the Director of Data Science at #syGlass, and here is a video of #3Ddata from C Wolff the MBL @mblscience.bsky.social 🔬
#BioImaging #SciComm
For #3DThursday we’re introducing Dynamic Depth color mapping! It encodes distance with smooth depth-aware gradients so layered structures pop without losing context.
🔬 #MicroCT of a P1 mouse
🥼 Hsu Lab, Baylor, @cwloganhsu.bsky.social
🎬 syGlass.io
#Microscopy #SciComm #3DVisualization #syGlass
The #mesoSPIM community just celebrated 10 years of open-source light-sheet microscopy in Zürich! For #3DThursday, we're honoring Martina Schaettin & Fabian Voigt’s iconic 3D chick embryo dataset — a luminous benchmark for open science and shared discovery.
#Microscopy #Lightsheet #syGlass
One of my favorite #syGlass keyframes yet!
👀 #3DThursday: Cross your eyes to see this super res pollen dataset in 3D! Good old fashioned stereo pairs in #syGlass bringing science to life. 🌿✨
🔬: Zeiss LSM 980 with Airyscan 2
🥼: Nat Prunet, @nat-prunet.bsky.social
🏛️: UNC Biological Microscopy Core: tarheels.live/biologymicro...
🎬: syGlass.io
Non-destructive testing for #3DThursday!🥽 Apple Vision Pro vs MetaQuest in a microCT.
🔬: Lumafield @lumafield.bsky.social microCT
🎬: syGlass.io, loading two projects at once
3D imaging like this is used to validate design, catch flaws, and build smarter devices.
#MicroCT #syGlass #VR #SciComm
🦐 High-res microCT of #Parhyale hawaiensis for #3DThursday! A powerful crustacean model for studying limb development, regeneration, and evo-devo.
🥼: Nipam Patel & Andrew Gillis, 2017
🏛️: University of Cambridge @cam.ac.uk
🎬: syGlass.io
#Parhyale #MicroCT #DevBio #EvoDevo #ModelOrganisms #syGlass
Pollen diversity #3DThursday!🌼🌾 Thanks to Nat Prunet's careful microscopy, we see ridges, spikes & pores that reveal how plants spread & survive.
🔬: @zeiss-microscopy.bsky.social LSM 980, Airyscan 2
🥼: @nat-prunet.bsky.social
🏛️: UNC Biological Microscopy Core
🎬: syGlass.io v2.4.0 #syGlass
Chicken balancing for #3DThursday!🐔 These utricle hair cells sense gravity & straight-line motion. We segmented them with #CellposeSAM in #syGlass.
🥼: Stefan Heller Group
🏛️: Stanford @stanfordmedicine.bsky.social
🎬: syGlass.io v2.4.0, out now!
#Neuroanatomy #Microscopy #3DVisualization #SciComm
