Engineered nucleocytosolic vehicles for loading of programmable editors Engineered nucleocytosolic vehicles for loading of programmable editors (ENVLPE) with enhanced CRISPR ribonucleoprotein (RNP) loading and stabilization enable the efficient delivery of gene-editing ef...

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ENVLPE, our system for VLP-based delivery of gene editors, is now published in @cellcellpress.bsky.social. We showed efficient delivery of base- and prime-editors in primary T cells & in vivo retinal models. All core constructs are available from @addgene.bsky.social.

Engineering Smart Delivery for Gene Editors

Engineering Smart Delivery for Gene Editors 🧬
👉 t1p.de/vmdc9

Researchers from #HelmholtzMunich & @tum.de created ENVLPE – a modular, virus-like system that delivers CRISPR/Cas9 tools into cells with unprecedented efficiency.

#GeneEditing #CRISPR #CancerTherapy