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Posts by Diego Safian

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New Pre-Print Alert!

Evolving initial conditions: an alternative developmental route to morphological diversity

with Shannon Taylor and @jamesehammond.bsky.social

www.biorxiv.org/content/10.6...

1 day ago 123 48 6 2

Thrilled to present our comparative study on the evolution of zygotic genome activation (ZGA)!! 🥚🧬

Amazing PhD work of @campobes.bsky.social together with @fedemantica.bsky.social and many collaborators! @melisupf.bsky.social @crg.eu. Thread below 1/15

www.biorxiv.org/content/10.6...

2 days ago 114 57 4 9
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Interested in miRNAs, early animal evolution, and RNA biology? We’re recruiting a BBSRC-funded Postdoctoral Research Associate @bristolbiosci.bsky.social #Postdoc #microRNA #RNAbiology
Apply by 14 May 2026. 👉 www.bristol.ac.uk/jobs/find-in...

2 days ago 31 15 0 1
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Perspective helps a little.

2 weeks ago 22 7 0 0

This looks very cool 😎

🔗 to download: github.com/RegenImm-Lab...

2 weeks ago 5 3 0 0

🔥 New paper out now!
Do ectotherms actually adjust their physiology to cope with daily temperature swings? Our latest meta-analysis suggests… not really. Check it out now: doi.org/10.1098/rstb... and the other great studies in this special issues on #EmbracingVariability #PhilTransB#ThermalBiology

1 month ago 17 6 0 0
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Florent Murat Fish Evolution, Genomes, and Reproduction

Our lab is hiring a postdoctoral researcher with expertise in bioinformatics, evolutionary genomics and single-cell data analyses, to explore the evolution of reproductive organs across fishes. We are located in Rennes, France (INRAE-LPGP). For more details: florentmuratwebpage.wordpress.com

1 month ago 9 12 0 0
Chelodina longicollis, Eastern Long-necked Turtle. Melbourne Museum. 
Photographer: David Paul, Source: Museums Victoria

Chelodina longicollis, Eastern Long-necked Turtle. Melbourne Museum. Photographer: David Paul, Source: Museums Victoria

I hear you want novelty🦎->🐢,
chromosome evolution 🧬,
sex determination🩷,
link population history📈 & climate🌏🌡️?

Or you share my love for wonderfully weird animals?

Side-necked turtle genomes reveal chromosomal dynamics, skeletal innovation and cancer resistance
www.biorxiv.org/content/10.6...

A 🧵

1 month ago 11 6 1 0
Figure showing 3 panels,(A) a picture of annelid Capitella teleta on black background, (B) a cladogram with major biological model organisms showing the phylogenetic position of C. teleta and (C) schematics of the 10 chromosomes of C. teleta

Figure showing 3 panels,(A) a picture of annelid Capitella teleta on black background, (B) a cladogram with major biological model organisms showing the phylogenetic position of C. teleta and (C) schematics of the 10 chromosomes of C. teleta

New from @chemamd.bsky.social lab @qmulsbbs.bsky.social Collab with Elaine Seaver, @baxevanislab.bsky.social @neva-meyer.bsky.social @abhinavsur.bsky.social

New chromosome-level assembly for Capitella teleta 🪱

academic.oup.com/gbe/advance-...

#DevBio
#WormWednesday
@genomebiolevol.bsky.social

1 month ago 26 15 0 1
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🚨 Job Alert - Please share! 🙏

Interested in 3D gene regulation in development & evolution? 🤓🧬

💥 Our lab at @cabd-upo-csic.bsky.social is expanding!

We’re recruiting:
✅ PhD students
✅ Postdocs
💻🧪 Experimental or computational backgrounds welcome

👇 Details below

1 month ago 41 38 1 5
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The molecular evolution of vertebrate organs - Nature Ecology & Evolution This Review discusses recent advances in the molecular evolution of vertebrate organs, including rates of evolution of organs and cell types, molecular mechanisms of organ evolution and how complex tr...

New Review 👇

The molecular evolution of vertebrate organs: www.nature.com/articles/s41...

Margarida Cardoso-Moreira discusses rates of evolution of organs and cell types, molecular mechanisms of organ evolution and how complex traits contributed to the diversification of vertebrates.

1 month ago 13 10 0 0
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Preprint Editors – Development's next step into the preprint landscape Summary: This Editorial announces a call for Preprint Editors in Development to help expand the journal's relationship with preprints by curating our ‘In preprints’ articles.

New from @dev-journal.bsky.social: we're launching a new initiative and hiring Preprint Editors to help navigate the growing world of preprints in developmental & stem cell biology

Join our community & shape the future of research

journals.biologists.com/dev/article/...

1 month ago 55 39 1 0
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The molecular evolution of vertebrate organs Nature Ecology & Evolution - This Review discusses recent advances in the molecular evolution of vertebrate organs, including rates of evolution of organs and cell types, molecular mechanisms...

Our internal organs are evolutionary marvels. New technologies are transforming our understanding of the evolution of vertebrate organs. You can find more by reading here:
rdcu.be/e5EgU
#EvoBio #EvoDevo 🐟🦎🐢🦇🐊🦜

1 month ago 141 54 2 5
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Join us in Vienna for the biggest international 'FISH' meeting in 2026! No matter which fish is your favorite model - zebrafish, medaka, killifish, cavefish, Danionella, cichlids, stickleback, you name them...- this meeting is for you!

www.ezm2026.org

Abstract submission deadline is March 15th.

1 month ago 27 16 3 3
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We have a postdoc position available. Please forward to anyone who may be interested.

1 month ago 26 36 1 2

New Preprint!! 🦐🪰🦀

In this study we compared moulting gene expression across insects and crustaceans. #insects #crustaceans

Thread ⬇️ (1/6) www.biorxiv.org/content/10.6...

2 months ago 11 7 2 2
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The PopGen Vienna Seminar series schedule is ready for the next term (March-June). It's jam-packed with fantastic speakers in #evolution, #genetics, #genomics, #popgen, and more! Details and streaming link signup can be found on our website popgen-vienna.at/news/seminars/

2 months ago 25 17 1 2
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Very interesting and thorough discussion of the history and challenges of the #genotype -> #phenotype mapping.
A genetic approach, of course. Are we missing something in that 'missing #heritability'?
academic.oup.com/genetics/adv...

2 months ago 8 4 0 0
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Annotating genomes at increased scale and resolution Nature Reviews Genetics - In this Review, Ji et al. overview how rapidly advancing experimental and computational methods are enabling improved and automated annotation of gene structure and...

Our new review on genome annotation just appeared in @naturerevgenet.bsky.social, with a particular focus on the human genome, with Hayden Ji and Mihaela Pertea: rdcu.be/e4mI1

2 months ago 24 12 0 0
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Can we accurately map cell family trees using mtDNA? Excited to share MitoDrift, a high-precision single-cell lineage inference tool, enabling reliable mapping of lineage history to cell phenotypes. doi.org/10.64898/202...
Joint with @gaoteng.bsky.social. @bloodgenes.bsky.social @jswlab.bsky.social🧵

2 months ago 20 6 1 2
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Interested in the evo-devo of the mammalian cerebellum? This review is a must-read!

Really happy to have contributed to this work, led by @marisepp.bsky.social , together with @ioansarr.bsky.social .

2 months ago 15 7 0 0
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Symbiotic entrenchment through ecological Catch-22 A symbiotic rove beetle develops a stealth phenotype by silencing production of its hydrocarbon pheromones, enabling it to infiltrate ant colonies, steal ant pheromones, and achieve social acceptance ...

Symbiotic entrenchment through ecological Catch-22: Cell www.cell.com/cell/fulltex...

2 months ago 11 8 2 2

This paper marks the end of a long but rewarding project - and the start of something new (more below👇).

Massive thanks to @kaessmannlab.bsky.social, @ioansarr.bsky.social, @tyamadat.bsky.social, our amazing collaborators @steinaerts.bsky.social, Stefan Pfister, Rüdiger Behr and the entire team! 💙

2 months ago 24 2 2 1
Throat coloration in common wall lizards (Podarcis muralis). From top to bottom: White morph with the characteristic green and black coloration of the nigriventris syndrome; White morph with the ancestral brown phenotype; yellow and orange morphs from populations where individuals show varying expression of the nigriventris characters.

Throat coloration in common wall lizards (Podarcis muralis). From top to bottom: White morph with the characteristic green and black coloration of the nigriventris syndrome; White morph with the ancestral brown phenotype; yellow and orange morphs from populations where individuals show varying expression of the nigriventris characters.

Two new Science studies on lizard coloration reveal how a delicate interplay of genetics, environment, and social dynamics can either preserve or erase polymorphic diversity in species.

📄: https://scim.ag/4srYKHi
📄: https://scim.ag/4qCcsWn

3 months ago 48 11 0 0
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Enforced specificity of an entrenched symbiosis Wagner et al. uncover how the specificity of a myrmecophile rove beetle to its single host ant species arises not from sensory specialization on host cues. Instead, constraints on dispersal and aggres...

Interesting new research showing how even slight fitness differences in host shifting can constrain what could be a generalist ant symbiont to one particular host species.

3 months ago 21 2 0 0
Senior Bioinformatician - Biodiversity Cell Atlas Do you want to help us improve human health and understand life on Earth? Make your mark by shaping the future to enable or deliver life-changing science to solve some of humanity’s greatest challenge...

Open Senior Bioinformatician position at
@sangerinstitute.bsky.social
Tree of Life, to work on the Biodiversity Cell Atlas initiative with @marakat.bsky.social and me.

📅 Apply by January 18
🔗 sanger.wd103.myworkdayjobs.com/en-US/Wellco...

Please share with anyone who might be interested!

3 months ago 20 30 0 1
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Sex differences in tissue-specific immunity and immunology Biological sex exerts a substantial influence on the immune system and immune-related diseases. Males are more susceptible to the acute effects of viral disease and certain cancers, whereas females ex...

Researchers in a recent #ScienceReview examine the influence that biological sex exerts on the immune system and immune-related diseases.

Learn more: https://scim.ag/48YKHAe

3 months ago 36 9 0 1
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Decoding cnidarian cell type gene regulation - Nature Ecology & Evolution This study reconstructs the gene regulatory networks that define cell types in the sea anemone Nematostella vectensis, providing a valuable resource for comparative regulatory genomics and the evoluti...

This study reconstructs the gene regulatory networks that define cell types in the sea anemone Nematostella vectensis, providing a valuable resource for comparative regulatory genomics and the evolution of new cell types 🧪 www.nature.com/articles/s41...

3 months ago 5 3 0 0

Anouk Necsulea, @maelledaunesse.bsky.social and myself are organising a symposium at SMBE this year.

Send us all of your abstracts!!

4 months ago 5 3 0 0
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#Mastodon, the Command Center for Large-Scale Lineage-Tracing Microscopy Datasets, is finally heading for publication (well, let's see). To #cite or not to cite shall no longer be the question 🙃, because the #preprint. Software is available in every #Fiji near you.

www.biorxiv.org/content/10.6...

4 months ago 112 48 1 1
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