Another fresh preprint from the lab!
Menarche marks an inflection point for female brain and mental health trajectories. This milestone may identify a critical window for screening.
This is an effect you don't need stats to see (though we did those too).
Led by @carinaheller.bsky.social 🧵👇
Posts by Bart Larsen
🚨Preprint Alert 🧠
Our new preprint „Menarche onset is an inflection point for mental health and brain development“ is now online!
👉 Preprint available here: www.biorxiv.org/content/10.6...
Very excited to announce our new preprint, led by @hollysully.bsky.social, that presents, benchmarks, and validates a method to estimate brain iron content from routine fMRI scans!
It comes complete with a BIDS app!
Check out the preprint and thread below!
doi.org/10.64898/202...
Updated preprint: doi.org/10.1101/2025...
We have improved DELSSOME and showed that we can accelerate the estimation of two new biophysical models. By collating 12,005 individuals, we derive normative trajectories of cortical E/I ratio across the lifespan ...
We think of white matter as the highways of the brain. But when we followed development along those highways, we were surprised. The journey is more complex than we thought. My final PhD paper, “Two Axes of White Matter Development”, is now out in @natcomms.nature.com! 🛣️🧠✨
🔗 bit.ly/wm2axes
Amazing! This is sorely needed. Thank you!
“These findings provide clear evidence that data collected on MTurk simply cannot be trusted.”
screenshot of article title & author team
New paper & a thread on the results 👇
‘Reward-specific learning parameters change across normative adolescent development and are blunted in youth with high risk for depression’
acamh-onlinelibrary-wiley-com.ezp3.lib.umn.edu/doi/full/10....
Ever wondered how white matter tracts actually map onto the cortical hierarchy and cognition—beyond the usual “projection vs association” labels?
Our new preprint tackles exactly that! 🧠✨ doi.org/10.64898/202...
Thread below 🧵
Very happy to share our paper on the "summer slide" in kid's cognitive test scores is out now in @pnas.org!
We find a replicable dip in performance across multiple domains of cognition in >23,000 kids across 4 datasets!
Check out the 🧵 from @ariellekeller.bsky.social below! 👇
Excited to share our new review “Mapping interactions between adversity and neuroplasticity across development” in @cp-trendscognsci.bsky.social. We discuss how experience - particularly adversity - interacts with neuroplasticity during human development authors.elsevier.com/c/1mB5U4sIRv...
Department of Psychological & Brain Sciences at Johns Hopkins is inviting applications for 3 open-rank tenured/tenure-track positions in (1) Behavioral Neuroscience, (2) Cognitive Neuroscience, and (3) Cognitive Psychology.
pbs.jhu.edu/about/jobs/
Is the “standard workflow” holding back fMRI analysis?
Mass-univariate analysis is still the bread-and-butter: intuitive, fast… and chronically overfitted. Add harsh multiple-comparison penalties, and we patch the workflow with statistical band-aids. No wonder the stringency debates never die.
I can't recommend this fantastic new review from @valeriejsydnor.bsky.social enough! It does an amazing job of synthesizing the current state of the literature and then looking forward to provide a fresh perspective on how to move this work forward in humans. Check it out!
After years of development and testing, we are happy to present our work in "Diffusion MRI Processing in the HEALthy Brain and Child Development Study: Innovations and Applications"! www.biorxiv.org/content/10.1.... A thread:
I am beyond excited to announce that ggplot2 4.0.0 has just landed on CRAN.
It's not every day we have a new major #ggplot2 release but it is a fitting 18 year birthday present for the package.
Get an overview of the release in this blog post and be on the lookout for more in-depth posts #rstats
I still get chills
Meet Mike
*30+ years severe depression
*first hospitalized @ 13y
*20 meds
*3 rounds of ECT
*2 near-fatal suicide attempts
Mike felt joy for the first time in decades after we turned on his new brain pacemaker or PACE
see videos, read paper, follow thread
doi.org/10.31234/osf...
This paper truly exemplifies what is possible in the modern era of neuroimaging data. A beautiful and extremely impressive piece of work from @valeriejsydnor.bsky.social that was a treat to contribute to. Check it out!
OK, It is not just the HBCD release...
docs.hbcdstudy.org
It’s the ABCD Release time too!
docs.abcdstudy.org
nbdc-datahub.org
That means the ABCC 3.0.0 is live!!!
The largest release yet from the ABCD-BIDS Community Collection.
This is going to be fun!!
👇 Let’s dig in.
Excited to share that our paper is now in press at the British Journal of Psychiatry! Looking forward to presenting our work this Friday at #SOBP2025 in our symposium: "Does one size fit all? Subgroup Modeling of Brain-Behavior Relationships in Psychiatry" 🧠
#neuroskyence #neuroimaging #psychscisky
While the world burns, we cook up a new preprint! doi.org/10.1101/2025...
Biophysical modeling is a key tool to derive mechanistic insights into the brain. These models are governed by biologically meaningful parameters (unlike artificial neural networks), but the dirty secret ... 1/N
Awesome opening salvo from the lab of @lindenmp.bsky.social!! Super cool work that will stem many future directions!
Age-related differences in 1/f aperiodic EEG/MEG signals can be driven by cardiac rather than brain activity 👇
#interoception 🧠🫀 #neuroskyence
elifesciences.org/reviewed-pre...
AOC and Bernie in front of the rally crowd in Denver
Zoomed out crowd shot of 34,000 people in downtown Denver with Colorado mountains in the background
Tonight an unbelievable **34,000 people** gathered for our Denver rally to take on billionaires and win our country back.
This was the largest political gathering in Denver since Obama in 2008.
Also bigger than the 2024 DNC.
And the largest ever rally in Bernie’s career (and obviously, mine too).
We think of white matter as the brain's highways—uniform conduits between cortices. But what if we study development along tracts? Turns out the journey matters as much as the cortical destination! We're thrilled to share “Two Axes of White Matter Development” www.biorxiv.org/content/10.1...
1/n
For those who don't know, here are very real research costs that directs cannot cover - all fall within indirects: the buildings we work in (upkeep, maintenance, cleaning, etc), utilities, IT infrastructure, human resources, administrative staff, security, and lots more
Finally out in its polished form 🤩 New methodological avenues that help facilitate looking at individual brain functional organization in developmental populations 👶🧠
Psychedelic mental health research is booming—but how do we keep up with rapidly evolving evidence? 🌱 Our team proposes a living evidence synthesis approach to ensure clinicians, policymakers, and the public have access to the latest, most reliable data.
🔗 www.nature.com/articles/s44...
🧪🧵
hey -- i'm hiring a postdoc! the ad will be up shortly, but looking for someone with network neuroscience experience (very broadly). the position isn't tied to any specific project/grant, so lots of flexibility in terms of what you'd actually *do*. hmu if you might be interested/want to learn more!