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Posts by NealeLab

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Mining on the Moon is closer than ever, but challenges remain A scientist, an engineer, an archaeologist and a lawyer break down some of the physical, environmental, ethical and legal challenges of mining on the Moon.

Could this be my finest moment?

'"Your average space billionaire probably doesn't give a rat's arse about future generations," she said'.

I'm not sure I was expecting this to be quoted!
πŸ§ͺ

6 days ago 394 109 20 12

Complementary Holliday Junction observations now available to absorb from @martinxaver.bsky.social and coauthors!
www.biorxiv.org/content/10.6...

1 week ago 16 5 0 0
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How do authors want to use AI for review? - EMBO Reports EMBO Reports - A survey of researchers who compared AI-generated scientific reviews with journal-agnostic human peer review reveals that they overwhelmingly prefer using AI as a self-checking tool...

Commentary: How do authors want to use AI for review?
link.springer.com/article/10.1...

3 weeks ago 0 0 0 0
An infographic titled "The Chemistry of Spinach" explores iron content, vitamin A, and the "spinach teeth" sensation. It compares spinach to sirloin steak, noting that while spinach has more iron (2.6mg vs 2.5mg per 100g), only 1.7% is absorbed compared to 20% from steak. Low absorption is attributed to polyphenols. It highlights spinach as a source of beta-carotene and explains that "spinach teeth" are caused by oxalic acid reacting with calcium to form insoluble calcium oxalate crystals.

An infographic titled "The Chemistry of Spinach" explores iron content, vitamin A, and the "spinach teeth" sensation. It compares spinach to sirloin steak, noting that while spinach has more iron (2.6mg vs 2.5mg per 100g), only 1.7% is absorbed compared to 20% from steak. Low absorption is attributed to polyphenols. It highlights spinach as a source of beta-carotene and explains that "spinach teeth" are caused by oxalic acid reacting with calcium to form insoluble calcium oxalate crystals.

On #NationalSpinachDay, this graphic looks at the real story behind spinach’s iron content: www.compoundchem.com/2018/07/17/s...

#ChemSky πŸ§ͺ

3 weeks ago 56 22 3 1

Amazing to receive the @hfspo.bsky.social Research Grant to pursue the project I have been dreaming of since I started my lab..!!🧬: how meiotic drive impacts sex ratios in vertebratesπŸ‘©πŸ»β€πŸ”¬πŸ‘¨β€πŸ”¬ I am so fortunate to collaborate on this project with Jiri Hejnar at IMG and @amarques.bsky.social πŸŽ‰πŸ™πŸΌ

3 weeks ago 18 2 2 0

JOIN US!: PhD applications are still open.
Deadline extended until 6th April due to Easter break.
www.findaphd.com/phds/project...

4 weeks ago 1 1 0 0
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Meiosis alert! Last few days to register for #BMM2026.
Calling all postdocs/PhD students: your chance to meet the community, give a talk, present your poster!
Hosted at the beautiful Royal Society HQ in London this year!
www.rothamsted.ac.uk/event/xvi-br...

4 weeks ago 1 2 0 0
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Condensin loop extrusion properties, roadblocks, and role in homology search during recombination in S. cerevisiae - The EMBO Journal The in vivo mechanism, cis-acting roadblocks, and biological functions of DNA loop extrusion by eukaryotic SMC complexes remain incompletely defined. Here, we identify condensin-dependent Hi-C contact...

Condensin loop extrusion properties, roadblocks, and role in homology search
@aurelepiazza.bsky.social et al show yeast condensin unidirectionally extrudes long chromatin loops & contributes to biasing donor selection during recombinational DNA break repair
link.springer.com/article/10.1...

4 weeks ago 10 3 0 2
An infographic titled "The Chemistry of Daffodils" by Compound Interest for C&EN explains the flower's biological makeup. It features a bouquet of yellow daffodils and three main sections. The Aroma section highlights (E)-beta-ocimene for its woody scent, plus 1,4-dimethoxybenzene and (E,E)-alpha-farnesene. The Color section identifies carotenoids like zeaxanthin and beta-carotene. The Poison & Medicine section shows the toxic alkaloid lycorine and galantamine, used to treat Alzheimer's.

An infographic titled "The Chemistry of Daffodils" by Compound Interest for C&EN explains the flower's biological makeup. It features a bouquet of yellow daffodils and three main sections. The Aroma section highlights (E)-beta-ocimene for its woody scent, plus 1,4-dimethoxybenzene and (E,E)-alpha-farnesene. The Color section identifies carotenoids like zeaxanthin and beta-carotene. The Poison & Medicine section shows the toxic alkaloid lycorine and galantamine, used to treat Alzheimer's.

Spring is here in the northern hemisphere! Here's a graphic from the #PeriodicGraphic archives in @cenmag.bsky.social looking at the pigments that give daffodils their golden glow: cen.acs.org/articles/93/...

#ChemSky πŸ§ͺ

1 month ago 81 31 1 0
East Sands beach, St Andrews, in the sunshine (which happens more often than you probably think!)

East Sands beach, St Andrews, in the sunshine (which happens more often than you probably think!)

Chair in Earth Sciences position @uniofstandrews.bsky.social closing soon - Monday 23 March.

Very broad remit, so if you’d like to join our lovely school, and get to live in the super beautiful and friendly wee nation of Scotland, please apply!

www.st-andrews.ac.uk/earth-scienc...

βš’οΈπŸŒŠπŸ§ͺ

1 month ago 58 34 0 3
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Minutes of STFC's governing council, which are not publicly available, talk of the Council's head of strategy describing "a major shift of funding from curiosity-driven research to priority areas and targeted programmes".

Minutes of STFC's governing council, which are not publicly available, talk of the Council's head of strategy describing "a major shift of funding from curiosity-driven research to priority areas and targeted programmes".

Wow. @pallabg.bsky.social has a obtained leaked document from STFC Council suggesting the origin of the STFC funding crisis was a deliberate decision (by?) πŸ§ͺπŸ”­ www.bbc.co.uk/news/article...

1 month ago 17 6 1 0
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Associate Senior Lecturer/Assistant Professor in Molecular Microbiology The Department of Biology conducts research and teaching in many subject areas such as ecology, evolutionary biology, organismal biology and molecular biology. A total of approximately 300 people curr

Associate Senior Lecturer/Assistant Professor position in Molecular Microbiology available at Lund University, Sweden:
lu.varbi.com/en/what:job/...

1 month ago 25 52 0 1

@gdsc-sussex.bsky.social

1 month ago 1 0 0 0

www.biorxiv.org/content/10.6...

1 month ago 2 0 1 0
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Fantastic to share the work of @whgittens.bsky.social and Tom Powell. World-first detection of Topoisomerase 3 activity on chromosomes in vivo. Top3 maps to meiotic hotspots then migrates, indicating that branched Holliday junctions migrate codirectionally with transcription; resolve at the axis.

1 month ago 13 2 1 1

Three-legged race?

1 month ago 0 1 0 0

Some of my favourite plants πŸ™ƒ

1 month ago 1 1 0 0
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Two weeks left to get in your applications! ✍️
www.sussex.ac.uk/study/fees-f...

1 month ago 1 3 0 0
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Common variation in meiosis genes shapes human recombination and aneuploidy - Nature Analysis of data from pre-implantation genetic testing sheds light on the genetic basis of meiotic-origin aneuploidy, the leading cause of human pregnancy loss, identifying common genetic variants ass...

Pregnancy loss is common in humans, and chromosomal abnormalities are the leading cause. Using genetic data from ~140,000 IVF embryos, we show that maternal variation in meiosis genes influences recombination and aneuploidy risk.

First authors: @saracarioscia.bsky.social & @aabiddanda.github.io

2 months ago 121 55 1 5

www.biorxiv.org/content/10.6...

1 month ago 3 1 0 0
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After a long incubation, it is a huge pleasure to finally share the work of @luzmlopez.bsky.social, Jon Harper and their coauthors: "Localised negative feedback shapes genome-wide patterning of meiotic DNA breaks". @gdsc-sussex.bsky.social
www.biorxiv.org/content/10.6...

1 month ago 7 3 1 0
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I think you are right on the A-DNA...in addition to the tilts, there may well be 11 bases per turn here.

2 months ago 0 0 1 0

The one thing I *did* check for. And yet still got paranoid...

2 months ago 1 1 2 0
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Is it?! I'm just a lowly molecular biologist looking for a GIF... πŸ˜…
microbenotes.com/wp-content/u...

2 months ago 0 0 1 0

Now live on Find-A-PhD-dot-com:
Joint project between @labneale.bsky.social and @drjonbaxter.bsky.social @gdsc-sussex.bsky.social
Get in touch if you are interested in any and all of: Chromosomes, Genome Stability, Chromatin and DNA Topology in Mitosis and Meiosis.

www.findaphd.com/phds/project...

2 months ago 8 3 1 0

@science.org A small polymerase ribozyme that can synthesize itself and its complementary strand | Science www.science.org/doi/10.1126/... #RNA #ribozyme #evolution

2 months ago 32 8 1 1
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Indeed! And this depiction is just of one... www.nature.com/articles/sre...

2 months ago 5 2 1 0

NOW LIVE!: PhD opening joint with @drjonbaxter.bsky.social at @gdsc-sussex.bsky.social
Get in touch and apply if you are interested in any and all of: Chromosomes, Genome Stability, Chromatin and DNA Topology in Mitosis and Meiosis.
www.sussex.ac.uk/study/fees-f...

2 months ago 7 5 0 2
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Super strong representation from our department in SussexRNA at the RNA UK meeting in Windermere this week.

Many congrats to Jake, Courtney and Hope from the Ben Towler group, and Leandro Castellano, Lidia Vasilieva, Ben and Nikos for having abstracts accepted for presentation. πŸ‘

2 months ago 3 2 0 0

Beautiful! Is this in real time (20 seconds?)
(Speed also seem to slow over time?)

2 months ago 1 0 0 0