That thing at 100km looks like a beast.

Eating its own tail, the central dogma of molecular biology has come full circle!
🧬

New @currentbiology.bsky.social paper from Dr. Leila Elabbady on neural circuits that transform a touch stimulus into spatially targeted grooming.

Leila discovered a leg somatotopic map and used it to infer tactile receptive fields in the fly VNC connectome.

authors.elsevier.com/a/1mvu83QW8S...

A series of spontaneously blinking dyes for super-resolution microscopy - Nature Methods A series of spontaneously blinking dyes in the far-red range facilitate single-molecule localization microscopy. These dyes vary in their blinking properties and can be matched to the applications and...

Out in @natmethods.nature.com: More dyes. They work. Quite well. And blink. Pick the one that fits your target, your technique, and your labeling density. With too many collaborators and institutes to list, but anchored at @hhmijanelia.bsky.social www.nature.com/articles/s41...

Check out our new release on BioRxiv
co-lead by @pm-mueller.bsky.social

👉 rb.gy/lnrizk

special🙏 to
Severine Kunz #MDC
@leventallab.bsky.social
@andimicroscopy.bsky.social
@ewerslab.bsky.social and Kedar Narayan @NCI CCR VolumeEM

Are the days of discovering new cellular structures over?? /1

Last call!

Graphic announcing the MSCA Postdoctoral Fellowships 2026 call. It shows the opening date (9 April 2026), closing date (9 September 2026), and a budget of €399.05 million. The design features scientific visuals such as cells, a leaf, and lab elements on a dark background, with the European Commission logo at the bottom.

Big opportunities for researchers 🌍

We are investing nearly €400 million to help researchers share their work and collaborate with the best scientific teams across the EU.

The 2026 Marie Skłodowska-Curie Actions Postdoctoral Fellowships are now open.

More: link.europa.eu/PNxpxw

I am excited to share our most recent work collaborating with @centriolelab.bsky.social and @stearnslab.bsky.social to look at the ciliary base of mammalian multiciliated cells w/ cryo-ET, XL/MS, and U-ExM www.biorxiv.org/content/10.6...

🚨 Deadline approaching (Apr 16)! Don’t miss your chance to join our student-led #TheoreticalBiophysics workshop. Meals, accommodation + reasonable travel covered for accepted participants.

Apply ➡️ janelia.news/THB26

@allysonsgro.bsky.social @zamakany.bsky.social

Applications are open for the Junior Theoretical Neuroscientists Workshop which will take place July 21-24, 2026 at the Center for Computational Neuroscience, @flatironinstitute.org

Travel, lodging, and meals will be covered for accepted participants.
Application deadline: April 15, 2026

Deadline is approaching (April 16th). Send in your applications . All details here: www.janelia.org/you-janelia/...
Apply for this workshop at @hhmijanelia.bsky.social
intended as a "by the students, for the students" meeting.
@janeliaconf.bsky.social

Senior Director – Scientific Program Officer Primary Work Address: 4000 Jones Bridge Road, Chevy Chase, MD, 20815 Current HHMI Employees, click here to apply via your Workday account. The Howard Hughes Medical Institute (HHMI) advances the disco...

Join us in shaping the future of science! @hhmi-science.bsky.social is hiring a new Scientific Program Officer to support the #HannaGrayFellows #FHScholar programs

hhmi.wd1.myworkdayjobs.com/en-US/Extern...

Data-Driven AI for Neuroscience Organizers Carsen Stringer, HHMI/Janelia Research Campus Srini Turaga, HHMI/Janelia Research Campus Atika Syeda, HHMI/Janelia Research Campus Fabian Sinz, University of Göttingen Alice Wang,

📢 Applications are open! This meeting brings together scientists using data-driven #AI to analyze + model neural circuits and uncover how the brain performs complex computations. 🧠

Apply by May 28 ➡️ janelia.news/NAI26

@computingnature.bsky.social @sinzlab.bsky.social @srinituraga.bsky.social

🧵 New preprint led by @bingbrunton.bsky.social, @elliottabe.bsky.social, @lawrencehu.bsky.social

We gave a worm brain control of a fly body and it walked

What did we learn? Nothing, other than deep reinforcement learning is effective

We call it the digital sphinx

www.biorxiv.org/content/10.6...

Friday, 13:15 (Poster 2-048) at @cosynemeeting.bsky.social #cosyne2026: @allierced.bsky.social and @lappalainenjk.bsky.social present how they made GNNs learn interpretable circuit models from neural activity. Code: saalfeldlab.github.io/flyvis-gnn/

I have just arrived at @cosynemeeting.bsky.social ! During my flight, as I thought about opening remarks (and had a glass of wine), I got to reflect on why I love neuroscience. Maybe other folks are doing the same and would like to read or add, so I thought I'd do something unusual and share!

@mackelab.bsky.social is at @cosynemeeting.bsky.social #cosyne2026 in Lisbon with two posters presented by PhD students from the lab.
Thread below on the projects 👇

We opened 4 PhD positions at @humantechnopole.bsky.social together with Polimi (see 👇).

My lab offers a PhD project on "Computational Morphogenesis": use state-of-the-art machine learning methods together with realistic simulations to build digital twins of developing tissue.

Apply by March 26.

Looking forward to heading off to Cosyne next week, and excited to be part of a two day workshop about connectomics, with day one being about species comparison and day two about using data for constraining models. alleninstitute.github.io/connectomics...

Ping.

A central somatotopic map of the fly leg supports spatially targeted grooming www.biorxiv.org/content/10.64898/2026.02...

Excited to share our new paper (CVPR 2026 🚀): "MuViT: Multi-Resolution Vision Transformers for Learning Across Scales in Microscopy" which enables local predictions to use global context.
Great work led by @albertdm.bsky.social & another fun collab w @gioelelamanno.bsky.social! @scadsai.bsky.social

Yep, it lags a little. But still quite impressive considering that each "pixel" is a 150 MPixel multires image. Overall the total number of 'adressable' pixels in this 2D image are 225x225x150 Mpix = 7.6 Tera pixels. #ImageJ #Fiji #BigDataViewer

After 5 years of developing, a new preprint from the lab - introducing our workflow for comparative insect connectomics, aimed at democratizing connectomics. @erc.europa.eu @lundvision.bsky.social @biologylu.bsky.social Read it here: www.biorxiv.org/content/10.6...

Evolved Virtual Creatures by Karl Sims, 1994 Demo of simulated block creatures performing various evolved behaviors.

Christian Donlan of @theguardian.com unfortunately missed that #AnLife is exactly Karl Sim's evolved creatures www.karlsims.com/evolved-virt..., beautiful work from 1994, and not a recent AI wonder. Cute though! www.theguardian.com/games/2026/f...

People sitting on stairs discussing a project. Text highlighting the next EMBO Lab Leadership for Scientists in the Americas live online course running on17-20 March 2026 still has places available.

Scientists in the #Americas: spots still open for the @embo.org Lab #Leadership online course. Spread over 4 days, March 17-20, 9am-3:30pm NY time. Built for life science researchers. #EMBOLabLead Register before places fill up: www.embolableadership.org/course/embol...

Long Lake, Little Lakes Valley, Inyo National Forest, CA, photos from 2007, 2016, 2023 showing the same dead tree.

Some people are just mean though... And some places are just nice. That tree trunk ain't goin' anywhere 😀

We are excited to be recruiting a new tenure track group leader in the Structural Studies Division at MRC LMB! It is an amazing place to start your own lab.
@mrclmb.bsky.social

Please get in touch if you have any questions.
www.nature.com/naturecareer...

Accelerating Innovation in Biology HHMI’s $500 million over the next 10 years will support AI-driven projects and embed AI systems throughout the scientific process in labs across HHMI.

Join us in building foundational datasets and models for microscopy with @jakobtroidl.bsky.social and many others

AI Engineer Pre-Training: lnkd.in/eyEEV5nm
AI Engineer Post-Training: lnkd.in/eShVQ3y9
Data Engineer Data: lnkd.in/eCvm58xH
Data Engineer Pipelines: lnkd.in/ec6qGJkX

ai.hhmi.org