GitHub - eneskemalergin/z-fasta: ⚡ SIMD-accelerated FASTA indexer written in Zig. 15–17x faster than samtools faidx. mmap, zero dependencies, single binary. Produces byte-identical .fai output. ⚡ SIMD-accelerated FASTA indexer written in Zig. 15–17x faster than samtools faidx. mmap, zero dependencies, single binary. Produces byte-identical .fai output. - eneskemalergin/z-fasta

As a project to learn #Zig, I wrote z-fasta, a drop-in replacement for samtools faidx. It indexes ~17x faster using mmap/SIMD. It's early days, and I have a lot more planned, but I'd really appreciate any feedback or bug reports from the #Bioinformatics community!
github.com/eneskemalerg...

Pan-cancer N-glycoproteomic atlas of patient derived xenografts uncovers FAT2 as a therapeutic target for head and neck cancers Cell surface proteins offer significant cancer therapeutic potential attributable to their accessible membrane localization and central role in cellular signaling. Despite this, their promise remains ...

Big effort (> 7 years) from a large number of colleagues. Finally on BioRxiv and to be submitted in January

Pan-cancer N-glycoproteomic atlas of patient derived xenografts uncovers FAT2 as a therapeutic target for head and neck cancers

www.biorxiv.org/content/10.1...

The human proteomic revolution proceeds with high-throughput assessment, AI analytics, correlation with health and disease, drug interactions, biomarkers
www.cell.com/cell/fulltex...