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Posts by Sarah E Hancock

Abstract submission for the 6th Australian Cancer Metabolism Meeting closes today. Don't miss this chance to showcase your work to the Australian Cancer Metabolism community. www.acmm.au
#Cancer #Metabolism #CancerMetabolism #Sydney #Australia

3 days ago 2 2 0 0
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At an outdoor performance of Phantom of the Opera in Sydney Harbour tonight. Absolutely stunning location despite the weather.

6 days ago 0 0 0 0

Am I the only one who gets annoyed when the wrong picture of mass spec is used in a manuscript figure? e.g., an Orbitrap-based instrument was used for data acquisition, but the vector image shown in the figure is an Agilent QTOF (or worse, a QqQ). #TeamMassSpec #massspectrometry

1 week ago 11 1 0 0
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I'm on holidays with the kids this week, and every morning when the moon is still out they've been waving to the astronauts #artermis #artemisIi 🌕

2 weeks ago 7 0 0 0
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🔬 ACMM 2026 | Sydney | 20–22 May
Join us for the 6th Australian Cancer Metabolism Meeting, featuring leading international & national speakers including Rushika Perera, Isaac Harris, Lisa Butler, Renea Taylor and more.
🧬 Abstracts close: 20 Apr
📝 Registration closes: 6 May
👉 www.acmm.au

3 weeks ago 4 2 1 1

Wow even Avanti? That's odd to say the least.
Not sure if Larodan make those types of lipids.

3 weeks ago 1 0 0 0

Where are you normally buying them from? I'm in Australia and am still getting shipments from Avanti Polar Lipids (one arrived last week). Although those are a bit shorter than the phospholipids I typically work with. Cayman have recently expanded its lipid catalogue as well.

3 weeks ago 1 0 1 0
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🚀 The Lipid Network is now live!

A new platform designed to connect researchers across all areas of lipid biology.

Find collaborators, discover expertise, and help build a more connected lipid research community.

Join the network:
lipidnetwork.com

3 weeks ago 7 1 1 0
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What kinds of lipids are we talking about? Just fatty acids, or phospholipids, glycerolipids, sphingolipids etc.

3 weeks ago 0 0 1 0

If you're working in the field of lipids, then be sure to follow my #LipidSky feed, which collects lipid-related skeets from the past 7 days. If you find it useful then please give it a like!

1 month ago 1 1 0 0
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Lipids are everywhere in biology, but lipid researchers are often scattered across disciplines.

Membranes, metabolism, infection, neuroscience, lipidomics… the field is huge, but the community isn’t always connected.

Something new is coming to change that.

Stay tuned. 🧬

1 month ago 9 3 1 1
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Registration is open for the 6th Australian Cancer Metabolism Meeting (ACMM2026), taking place 20–22 May 2026 in Sydney. 🔬 🧪 www.acmm.au

If you work in cancer biology, metabolism, oncology or translational research, we'd love to see you there!

1 month ago 4 4 1 0
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When your research assistant is a massive trekkie you get awesome lab archives entries such as this

2 months ago 3 0 0 0
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Registrations for the #Lipidomics #GRC close soon. Don't miss this chance to learn from and engage with leaders in the field #TeamMassSpec 🧪 www.grc.org/lipidomics-c...

3 months ago 2 1 0 0

😂

3 months ago 1 0 0 0
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Found on LinkedIn alongside text describing how PCR works. 😂. #TeamMassSpec #massspectrometry #science #badai

3 months ago 58 16 9 10

Super gross stuff

3 months ago 0 0 0 0

*inaccessible region. That's what I get for posting before coffee

3 months ago 0 0 0 0
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Fatberg the size of four buses likely birthed poo balls that closed Sydney beaches – and it can’t be cleared Exclusive: Secret report suggests fats, oils and grease accumulate in ‘inaccessible dead zone’ at Malabar plant, then dislodge when pumping pressure ‘rapidly increases’

Turns out the Sydney beach poo balls we analysed in late 2024 might be baby poo balls birthed from a giant fatberg stuck in an accessible region of Sydney's waste water system. #TeamMassSpec

www.theguardian.com/australia-ne...

3 months ago 2 0 3 0

#NHMRC Ideas grant success rate was 8.1% this year. This is not sustainable.

4 months ago 0 0 0 0

Super thrilled to have this one accepted at AnalChem last week. Nice way to see out the end of the year. 🎉 #lipidomics #TeamMassSpec

4 months ago 11 4 1 0
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Celebrating Dr Banks (@jasmineleighb.bsky.social) and Dr Govindäraj (@hemnaphd.bsky.social) who graduated last Friday! 👩🏻‍🎓 🎉
Wishing you the very best for the many exciting adventures to come!

4 months ago 5 2 2 0

@phenylauraline.bsky.social is on 🔥🔥🔥 taking out the Paul Korner Seminar awards for two consecutive years. #TeamMassSpec #lipidomics

4 months ago 4 0 0 0
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Gambling on the electricity market: summer heatwave edition

4 months ago 1 0 0 0

FTR I would totally have this student back for a PhD but she is international and we currently don't have any stipend funding support for her. I'm working on it but in the meantme actively supporting her other applications.

4 months ago 1 0 0 0
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The worst, especially when you're on >1 app with multiple interruptions.

4 months ago 1 0 1 0

RIP James Watson. I'll always remember you as the dude berating the cafeteria staff at CSHL because they served turkey bacon on the open day.

5 months ago 3 3 0 0

Our very own newly minted PhD @jasmineleighb.bsky.social is the @victorchang.edu.au Star Scientist for November. Best of all, she's currently looking for postdoc opportunities for 2026. Hit her up if you think she might be a good fit for your lab. #teammassspec #obesity #nad 👩‍🔬🧪

5 months ago 11 4 0 0

Pretty much :)

5 months ago 1 0 0 0
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Epoxidation-enhanced charge-switch derivatization for rapid profiling of monounsaturated fatty acid isomers Structural isomerism in monounsaturated fatty acids (MUFAs) presents a persistent challenge in lipidomics due to limited chromatographic resolution and indistinguishable mass spectral profiles. Moreover, many methods that overcome these limitations require specialized instruments or complex photochemistry typically not accessible in for those using standard lipidomics core facilities. We report a streamlined LC-MS/MS method that integrates N-(4-aminomethylphenyl)pyridinium (AMP)-based charge-switch derivatization with meta-chloroperoxybenzoic acid (mCPBA) epoxidation to enable rapid and sensitive profiling of MUFA double bond positional isomers. Charge-switching enables enhanced detection of fatty acids while epoxidation improves chromatographic resolution and produces diagnostic fragmentation patterns upon collision-induced dissociation (CID), enabling precise localization of double bond positions. The optimized workflow achieves baseline separation of 16:1, 18:1, and 20:1 MUFA isomers within a 20-minute gradient, with reproducible retention times and consistent epoxide yields. The method also supports partial resolution of polyunsaturated fatty acids (PUFA) and cis/trans isomers. Application to prostate cancer cell lines revealed distinct MUFA isomer profiles associated with aberrant fatty acid desaturase 2 (FADS2) activity, including elevated n-10 and n-12 isomers in tumorigenic lines. These results align with prior studies using other isomer-resolving techniques, validating the method’s analytical performance. This accessible and robust strategy expands the toolkit for lipidomics research, providing a method that is compatible with conventional LC-MS/MS workflows, positioning it as a practical solution for high-resolution isomer analysis in complex biological samples

I put this one up quietly on @chemrxiv.org before disappearing on annual leave for 3 weeks. It is a quick and useful technique for those of us who want to do isomer-resolved #lipidomics but don't have access to modified instruments. doi.org/10.26434/che... #teammassspec #massspec

5 months ago 8 2 1 0