Extremely beautiful!

BRAVO!!!!!!! So well deserved.

BIG ANNOUNCEMENT📣: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!🙀🥳 (thread 👇)

It is with great sadness that the University shares the news of the death of Professor Sir John Gurdon, founder of the @gurdoninstitute.bsky.social

Read our tribute to the visionary Nobel Laureate and watch an interview from 2012, just after he won: https://bit.ly/4mM8o3r

We have had a great final morning at #EDRC2025 with three fantastic keynote lectures by Maria Gambetta, Tor Erik Rusten and Silke Sachse

3, 2, 1 and we are on!!! #EDRC2025 is starting! Welcome to our more than 740 participants from more than 40 countries! Thank you to all our sponsors!

Mushroom bodies tiny regulates Sidekick localization to tricellular adherens junctions Highlighted Article: Localization of the cell-adhesion molecule Sidekick to tricellular adherens junctions requires specific extracellular domains and its intracellular binding partner, the PAK4 kinas...

Read the article ‘Mushroom bodies tiny regulates Sidekick localization to tricellular adherens junctions’ here: doi.org/10.1242/dev....

Congratulations!
So Sunday notifications are good. Nice!
My experience is that Friday notifications just before WE or holidays are bad, really bad...

Our new preprint is out !
We uncover how adult Drosophila muscles respond to injury through a coordinated dialogue between hemocytes, tracheal cells, and muscles.
Check it out and please share
@igdrennes.bsky.social

BTW, same goes for grant reviews...

Shame on the reviewers to be that lazy and disrespectful. I had similar suspicion with another publisher. Some claims of the reviewers were completely wrong. Discussed with editors about the issues without actually calling them AI generated. Is there a way to prove it was AI generated?

But it is a fraction of the price, and extremely robust (ours is a shared equipment for the institute).

My point is it is great to count objects and have a pretty picture with less background and blur (even though confocal remains way better), but I would be extremely cautious for intensity quantification.

We use it daily on Drosophila tissues. It gives pretty images, but it remains epifluorescence (more bleed through) and one must remain extremely careful with the "levels" seen on the screen.

Bravo!

After manuscript reviews full of inaccuracies which appear AI generated, and final grant rejection (despite excellent reviews), I will let the disappointment and anger pass, and will not review your manuscript tonight. I apologise for the potential delay, but you might thank me later.

Great ressource!

Multi-omic mapping of Drosophila protein secretomes reveals tissue-specific origins and inter-organ trafficking Secreted proteins regulate many aspects of animal biology and are attractive targets for biomarkers and therapeutics. However, comprehensively identifying the "secretome", along with their tissues of ...

I’m thrilled to share a @biorxivpreprint for my postdoc work in the @PerrimonLab🎉. Together with our collaborators, we built a tissue-specific atlas of circulating secreted proteins in Drosophila 🧬🪰🧪🗺️.
Thread below🧵
1/8
www.biorxiv.org/content/10.1...

That is a tough one to beat... But sometimes it is better these obviously bitter reviews that can be dismissed with the editors (once you have let the anger pass), than those who want to kill your paper by asking an endless list of unfeasible experiments (to which editors rarely, hum never, say no)

Congratulations!

Cell-type-specific nucleotide sharing through gap junctions impacts sensitivity to replication stress in Drosophila Boumard et al. demonstrate gap-junction-dependent tissue-scale nucleotide sharing, which impacts cellular sensitivity to perturbation of nucleotide homeostasis and replication stress. Drosophila wing ...

Very happy to share our latest lab publication!
The hard work of @bboumard.bsky.social, Gwenn Le Meur and collaborators!
Cell-type-specific nucleotide sharing through gap junctions impacts sensitivity to replication stress in Drosophila: Developmental Cell
authors.elsevier.com/a/1lDFi_Yv6z...

Serotonergic neurons regulate the Drosophila vascular niche to control immune stress hematopoiesis
#Drosophila

Drosophila Genetic Database The Drosophila Genetic Database, FlyBase, is on the brink of collapse due to the sudden termination of the FlyBase NIH grant, which includes salaries for 5 literature curators based at the University ...

#drosophila @flybase.bsky.social request emergency funding:
"As it stands, by the end of July, 2025, there will be no future updates to FlyBase, and in the worst case scenario access to the website will also be lost" => please donate!

www.philanthropy.cam.ac.uk/give-to-camb...

Drosophila Genetic Database The Drosophila Genetic Database, FlyBase, is on the brink of collapse due to the sudden termination of the FlyBase NIH grant, which includes salaries for 5 literature curators based at the University ...

Flybase lost all of the NIH support overnight - it is a disaster for the community. Please consider donating. I just did! www.philanthropy.cam.ac.uk/give-to-camb...

At the end of a seminar part of an interview process, after 15 minutes of question and a good exchange waiting to be last to talk: "What you propose is exactly what not to do..."

Many cells during development are exposed to caspase activation and yet survive. Why some die and not others ? We found out that the memory of previous caspase activation bias significantly later death comitment and bias death distribution and single cell decision
www.biorxiv.org/content/10.1...

📣 Junior PI Opportunity
Join CNRS Strasbourg to lead cutting-edge research on host-pathogen interactions in insects 🪰
450k€ package | Drosophila, RNA, immunity
IBMC + Labex NetRNA network
📅 Apply by June 30, 2025
🔗 ibmc.cnrs.fr/en/laboratoi...
#RNA #Insects #Drosophila #NetRNA #Immunity #JobAlert

PS: would be very interested to have your feed back on the specificity of these TRE / mRE-DsRed in muscles. Thanx

In our hands, even the control mutant mRE-DsRed were becoming pinkish with age. We used them for reporting JNK activity only in imaginal discs, where it was specific.

Congrats!