A mast cell receptor mediates post-stroke brain inflammation via a dural-brain axis Meningeal mast cells, via the receptor Mrgprb2/X2, orchestrate brain inflammation after stroke by recruiting and promoting the transfer of skull bone marrow neutrophils into the brain, highlighting th...

Very excited to share our new work out today @cellpress.bsky.social. Here, we propose that meningeal mast cells regulate brain inflammation after stroke by coordinating immune infiltration from the skull bone marrow, through the meninges, and into the brain!

www.cell.com/cell/fulltex...

Awesome seeing you in person ❤️❤️ And it was such an exciting talk!!!

I've also now made a Starter Pack for the #AntimicrobialPeptide field here:

go.bsky.app/JLHHzt1

Please let me know who I am missing! This is a very incomplete list so far. I also expect many will join Bluesky later. I will happily keep populating this list! 📣🧬🦠

Headshots of 102 women and non-binary scientists who are now assistant professors. At the bottom is the Leading Edge logo and www.leadingedgesymposium.org

Leading Edge is celebrating a milestone: 100 (actually 102!) new assistant professors!!! 🎉🥳🎊

Learn more about them:
www.leadingedgesymposium.org/fellows/

Applications are now open for the 2025 Leading Edge cohort! (Deadline Feb 3).

You do NOT need to be ready for the job market to apply.

Assistant / Associate Professor in Computational Neuroscience opening at University of Texas Dallas.
jobs.utdallas.edu/postings/28027

Type I IFN-mediated NET release promotes Mycobacterium tuberculosis replication and is associated with granuloma caseation Sur Chowdhury et al. report that Mycobacterium tuberculosis (Mtb) infection results in the release of neutrophil extracellular traps (NETs) that promote Mtb replication and associate with tissue damage. Blocking NET release results in better control of Mtb replication, revealing a strategy for treating these deadly infections.

Very excited for this story to be out!! Check out our dissection of how type I IFN promotes NET release, which contributes to Mtb pathogenesis and is associated with granuloma necrosis. Congratulations to all authors!! www.cell.com/cell-host-mi...

I’ve made a Starter Pack of #innateimmunity and #inflammation researchers to follow! Please contact me to get added or to suggest others to add. We are just getting started 😎
#immunosky
#academicchatter
go.bsky.app/QqJ9AgB

Leading Edge Fellows Join the conversation

go.bsky.app/He3EAcq

new app, same drum 🥁! Leading Edge supported me through my postdoc and continues to be and incredibly valuable community for me as a start my lab. Follow @leadingedgeprogram.bsky.social for more information about applying...and apply!!