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Posts by Brett Collins

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Man Finally Good Enough At New Hobby To Understand How Bad He Is At It ST. LOUIS—Voicing frustration as he discussed his lack of even the most rudimentary skills, local man Henry Right told reporters Monday that he had finally gotten good enough at his new hobby to under...

“I picked up the guitar last year, and after endless hours of private lessons and online tutorials, I’ve now learned enough to realize that I have no idea what I’m doing with this instrument,” said the 45-year-old content strategist

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Only 9 years to go from today, until AI cures all disease 🚀 🚀🚀

Really looking forward to it!

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Don't be shy to take on a little two-week side project. These five months will be the most precious three years of your academic journey.

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How your email finds me

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AAAAAAAAAAAAHHHHHHHHH

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You know what modern comics are missing? Sea monkeys!

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Development of the fluorescent probe CenSpark for labeling centrioles and cilia - Nature Chemical Biology CenSpark is a dual-ligand fluorescent probe binding simultaneously inner and outer microtubule sites, a configuration unique to doublet and triplet microtubules, enabling selective live imaging of cen...

Very cool probe to label doublet MTs and therefore centrioles across different species and set ups (from live imaging, STED and expansion)!😍

www.nature.com/articles/s41...

2 days ago 28 10 0 2
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On April 19, 1898, Camillo Golgi first described what we now call the Golgi apparatus - a structure so striking and unusual that it took more than 50 years for scientists to accept it wasn’t just an artefact.

April 19 is #GolgiDay! Celebrate the cell’s most iconic and best organelle.

3 days ago 49 11 2 2
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I am so excited to share our new findings with you! We provide the structural evidence for a direct protein-to-DNA information pathway, showing how a bacterial enzyme 'reads' its own structure to 'write' DNA. www.science.org/doi/10.1126/...

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This is Mav. She couldn't contain her excitement during her ultrasound. Appreciated the attention and honestly a cold, wet belly rub is still a belly rub. 13/10 (IG: duluthveterinaryhospital)

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Check out our new release on BioRxiv
co-lead by @pm-mueller.bsky.social

👉 rb.gy/lnrizk

special🙏 to
Severine Kunz #MDC
@leventallab.bsky.social
@andimicroscopy.bsky.social
@ewerslab.bsky.social and Kedar Narayan @NCI CCR VolumeEM

Are the days of discovering new cellular structures over?? /1

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One more Asgard archaeon! Meet Nerearchaeum marumarumayae from the microbial mats of Shark Bay, Australia. It interacts with #bacteria via intercellular nanotubes 🧬!
#microbiology #archaea #eukaryotes #MicroSky #ArchaeaSky
@currentbiology.bsky.social
www.cell.com/current-biol...

1 week ago 20 11 1 0
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1/ Excited to share our preprint! 🥳

Degradation of aromatic compounds, including BTEX pollutants, requires highly endergonic aromatic ring reduction. Using #cryoEM and in situ #cryoET, we show how BCRII couples electron bifurcation modules in one giant redox machine

www.biorxiv.org/content/10.6...

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Congratulations to our Head of Department, @mjafreeman.bsky.social, awarded the @biochemsoc.bsky.social Centenary Award!

This recognises his contributions in the field of intramembrane proteases and pseudoproteases, and his commitment to supporting talent within the scientific community.

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Dr Tom Deegan from University of Edinburgh awarded The Colworth Medal by The Biochemical Society 2027 Awards.

Dr Tom Deegan from University of Edinburgh awarded The Colworth Medal by The Biochemical Society 2027 Awards.

Congratulations to Tom Deegan who receives the Colworth Medal in 2027! Pioneering work from the Deegan Lab has redefined our understanding of eukaryotic DNA replication and provided conceptual and technical frameworks that continue to drive new discoveries across molecular biology.

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Portrait of Dr Laura Lorenzo-Orts, Institute of Molecular Biology, Germany, recipient of the 2027 Biochemical Society Early Career Research Award.

Portrait of Dr Laura Lorenzo-Orts, Institute of Molecular Biology, Germany, recipient of the 2027 Biochemical Society Early Career Research Award.

Bridging the gap between biochemistry and developmental biology, we are excited to announce Laura Lorenzo Orts as a recipient of an Early Career Research Award in 2027! Laura's new lab focusses on understanding the mechanisms that activate mRNAs during early development.

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The Biochemical Society 2027 Centenary Award presented to Professor Matthew Freeman from University of Oxford, UK.

The Biochemical Society 2027 Centenary Award presented to Professor Matthew Freeman from University of Oxford, UK.

A leader in the cell biology of signalling, the 2027 Centenary Award is presented to Matthew Freeman in recognition of his pioneering discoveries into the biological significance and mechanisms of rhomboid intramembrane proteases and pseudoprotease and unwavering commitment to mentorship!

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Is the alt text AI generated? It is trolling Jurgen.

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Male bald speaker in blue shirt giving a presentation on early days of tomographic imaging in the 1980s, featuring Walter Hoppe and technical diagrams.

Male bald speaker in blue shirt giving a presentation on early days of tomographic imaging in the 1980s, featuring Walter Hoppe and technical diagrams.

Audience seated in a room attentively listening to a presentation, some holding notebooks or tablets.

Audience seated in a room attentively listening to a presentation, some holding notebooks or tablets.

Audience seated in a room attentively listening to a presentation, some holding notebooks or tablets.

Audience seated in a room attentively listening to a presentation, some holding notebooks or tablets.

Female researcher presenting colorful microscopic images at Max Planck Institute for Biophysics during the EMBO Practical Course on “In-situ structural biology by Cryo-FIB and Cryo-ET”.

Female researcher presenting colorful microscopic images at Max Planck Institute for Biophysics during the EMBO Practical Course on “In-situ structural biology by Cryo-FIB and Cryo-ET”.

We’ve kicked off our @embo.org Practical Course on #cryoFIB & #cryoET!

Participants from around the world are joining us this week for hands-on training, from lamella milling to tomogram reconstruction 🔬

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A surface rendered view of an endosome. The endosome surface is rendered in blue with dimples on it. In specific regions of the endosomal surface, clusters of proteins are seen as aggregates of blobs, coloured in yellow and red.

A surface rendered view of an endosome. The endosome surface is rendered in blue with dimples on it. In specific regions of the endosomal surface, clusters of proteins are seen as aggregates of blobs, coloured in yellow and red.

🚨New paper out today in @acs.org ACS Nano, showing how expansion microscopy can visually quantify the cell surface receptor turnover mediated by signalling & receptor organising machineries on the surfaces of endosomes, some of the smallest organelles in cells. 🧪 🔬 1/ pubs.acs.org/doi/10.1021/...

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"This is a new piece, it reflects feelings of neglect, abandonment and broken promises. I call it "WHERE'S MY FUCKING DINNER '"

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"America is now a Mel Brooks movie.

“Open the Strait of Hormuz or I’m closing the Strait of Hormuz”"

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The cartwheel was first visualized ~70 years ago in the symbiont Trichonympha in the wood termite gut. We’ve discovered the cartwheel’s secret: a unique zigzag stacking of SAS-6 tetramers that facilitates the iconic 9-fold symmetry of cilia.

#cellbiology #teamtomo #SAS6 #cartwheel

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One of biggest mysteries in biology: how did complex eukaryotic cells evolve from simple microbes? ~1.8 billion years ago, an archaeal cell likely merged with a bacterium to form the first eukaryotic cell, but can we ever find direct evidence of this transformative event? 🦠 🚶‍♂️

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Tabby stands on hind legs with one paw outstretched toward a TV displaying a capsule above water.

Tabby stands on hind legs with one paw outstretched toward a TV displaying a capsule above water.

NASA failed to predict the real splashdown risk.

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Splashdown confirmed!

Let us welcome the crew of Artemis II back to our pale blue dot.

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An Asgard archaeon from a modern analog of ancient microbial mats (Current Biology)

Beautiful microscopy of an Asgard archaeon, in the same family as Lokiarchaea, in syntrophy with a sulfate-reducing bacteria

Very very nice paper we saw in preprint form:
www.cell.com/current-biol...

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Remy the cat sees a duck for the first time 😂

TT: McKenna

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From Asgard to Earth: Tiny tubes may reveal the moment complex life began Stromatolites—and their close relatives, microbial mats—could be mistaken for what seems like a bunch of old dark rocks. But instead, they are dense, layered communities of microbes. Long before compl...

Our paper is out today! See this news article on it. Asgard archea have some cool proteins. If you are interested in protein evolution it’s a really exciting space. I’m lucky to be a structural biologist in the age of DL🧬🧶 @brendanburns999.bsky.social @iduggin.bsky.social @debnathghosal.bsky.social

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