Out today in @cp-cell.bsky.social! We studied how environmental stresses like high-fat diets today can prime tumorigenesis months to years in the future (1/n)

High-fat diets make liver cells more likely to become cancerous Liver cells exposed to too much fat may revert to an immature state that is more susceptible to cancer-causing mutations.

Study by @ragoninstitute.bsky.social, @mitkochinstitute.bsky.social, @broadinstitute.org team - including @constantine-sci.bsky.social, @drshay.bsky.social, and @shaleklab.bsky.social - suggests a high-fat diet puts liver cells in a state that makes them more susceptible to cancer-causing mutations

NIH Funding Has Stagnated Since 2003 This Viewpoint explores how funding has changed at the National Institutes of Health over time and discusses how continued investment is necessary to maintain the current level of biomedical research.

"The NIH budget has not increased in more than 20 years despite research being more expensive to conduct. This is a necessary data point for policymakers to consider as they determine funding priorities." 🧪

jamanetwork.com/journals/jam...

Harvard University Harvard University is devoted to excellence in teaching, learning, and research, and to developing leaders who make a difference globally.

Harvard redid its whole homepage to push back against the administration’s demands. I mean, this is just a website but I think it’s kind of a great PR move: www.harvard.edu

Short-term effects of high-protein, lower-carbohydrate ultra-processed foods on human energy balance - Nature Metabolism This single-blind crossover trial shows that the short-term consumption of protein-enriched ultra-processed foods does not prevent overeating but favourably affects energy partitioning.

New data on why ultra-processed food (UPF) intake should be limited. Adding protein to UPF didn't reduce overeating in a randomized, crossover study
www.nature.com/articles/s42... @naturemetabolism.bsky.social

NIH Grants Fueled $95 Billion In FY 2024 Economic Activity, Finds New Report National Institutes of Health grants generated almost $95 billion in economic activity nationwide in FY 2024 according to a new report by United for Medical Research.

New report shows that NIH grants fueled $95 billion in economic activity and 407,782 jobs in 2024.

That's not to mention the countless lives that biomedical research has saved.

Show me a better investment than that.
www.forbes.com/sites/michae...

An enormous amount of work, to tailor models to human liver cancer for precision therapy -congratulations Tom Bird and team 👏 #gastrosky #medsky #immunosky #liversky

Get excited #liversky! #TLM24 party is starting!

Great start to #TLM24 with the Basic Science session! Fantastic discussions on lipid metabolism reprogramming and HCC. #liversky

Would love to be added as well! Thanks!