#PediatricResearch #MentalHealth #Psychiatry #Leadership #AcademicMedicine #CincinnatiChildrens #WeAreCincyKids

Suzanne Sampang Appointed Director, Division of Child and Adolescent Psychiatry - Research Horizons The board-certified physician and leader brings more than two decades of clinical, educational and leadership experience to the role.

Suzanne Sampang, MD, has been named director of the Division of Child & Adolescent Psychiatry at Cincinnati Children's. With 20+ years of leadership in pediatric mental health, she will help advance research, collaboration & innovation across the field.

An international research team led by our experts is making AI in pediatric mental health more accurate. By improving how algorithms learn from clinical notes, researchers reduced gender bias in anxiety detection by up to 27%—without sacrificing performance.

🔗 https://ow.ly/ZZ4o50YKCbB

@cincychildrens.bsky.social #HealthEquity #PedsResearch #SickleCellDisease #WeAreCincyKids

Road to Researcher: Lori Crosby, PsyD - Research Horizons The researcher-psychologist shares how her work in behavioral medicine and community-engaged research is advancing care for sickle cell disease.

What does it take to move from clinical care to research that impacts entire communities? Lori Crosby, PsyD, shares her journey—from an unexpected start in research to leading community-engaged work focused on sickle cell disease and health equity. Read the Q&A:

We’re partnering with New Zealand‑based BioOra to advance safer CAR‑T cell therapy for children with leukemia. Led by Dr. Stella Davies, this clinical trial is accelerating what’s possible for pediatric patients.

Hear from Davies below and learn more on our science blog:
https://ow.ly/hMzF50YK1CB

Despite low uptake, a study in The American Academy of Pediatrics found fewer flu‑related hospitalizations outpatient visits among vaccinated children. Vaccine effectiveness ranged from 34% to 60%. Cincinnati Children’s was one of 7 hospitals in the CDC's NVSN.
👉 https://ow.ly/pPVa50YH36J

Published in: @epilepsiajournal.bsky.social
#Epilepsy #ChildHealth #ClinicalTrials #PediatricResearch

Adherence Feedback Reduces Seizures in Children - Research Horizons

Can adherence feedback improve seizure outcomes for children with epilepsy? New research says yes. A multi-center clinical trial led by our experts found that digital reminders, education, and individualized feedback improved medication adherence and reduced seizures.
Read more on our Science Blog:

CAR T-cell therapy and indications for pediatric rheumatology: Structured overview of applications, risks, and considerations @cincyresearch.bsky.social
www.sciencedirect.com/science/arti...

Monoclonal Antibody Fremanezumab Shows Strong Efficacy in Treating Pediatric Migraine | Neurology Today

Cincinnati Children’s researcher Andrew Hershey, MD, PhD, had his @nejm.org study featured in Neurology Today.

The study showed that the adult migraine medication fremanezumab provides meaningful relief for children—leading to FDA approval.

@aanmember.bsky.social @cincychildrens.bsky.social

EoE: The Fifth Member of the Atopic March - Research Horizons

Children with atopic dermatitis are 10x more likely to develop eosinophilic esophagitis by age 8, according to new research from our experts. The study, published in @jacionline.bsky.social, supports adding EoE to the atopic march and could improve care.
Learn more: https://ow.ly/Qwj450YCrcs

Single-Cell Study Reveals How Immune Memory Cells Remember Threats - Research Horizons

How does the immune system respond so quickly to familiar threats? 🧬

New research from our experts, published in @cellpress.bsky.social, reveals that memory T cells are pre‑programmed for rapid defense—findings that may shape vaccine design and treatments for immune‑mediated disease. Read more:

Pediatric pneumonia guidelines get first update in 15 years For most children with complicated pneumonia, a less aggressive treatment approach is favored for those with small or moderate pleural effusions, according to updated guidance. The Infectious Diseases...

Updated pediatric pneumonia guidelines—first in 15 years—highlight a shift toward less aggressive care for many children, driven by clinical research. Cincinnati Children’s Dr. Samir S. Shah helped shape the recommendations. Read his insights:
@pidsociety.bsky.social @samirshahmd.bsky.social

Why Do Women with IBD Face Higher Risk of Pregnancy Complications? - Research Horizons

Why do women with IBD face higher pregnancy risks? New research from our expert's links reduced KLF2+ CD4 T cells to infertility and complications—offering insight into the biology behind these challenges. Learn more:
@pnas.org @babiesresearch.bsky.social
#WomensHealth #Microbiome #MaternalHealth

Congrats to our experts who are part of the eMERGE Network, advancing how genetic risk is shared responsibly. Learn more about the study on our Science Blog: scienceblog.cincinnatichildrens.org/yes-genetic-...

@geneticssociety.bsky.social @genomeweb.bsky.social #GenomicMedicine #HumanGenetics

$10.3M NIH HEAL Grant Powers a New Era in Pediatric Chronic Pain Research - Research Horizons Chronic pain affects millions of children and teens, disrupting school, sleep, sports, friendships, and mental health. Yet even as pediatric pain clinics have expanded, families still ask a question science has struggled to answer: Why does pain continue when the injury or illness is gone?

Chronic pain affects millions of children, but why it persists isn’t fully understood. A new $10.3M NIH HEAL grant supports Cincinnati Children’s researchers working to uncover causes and develop targeted therapies.

Learn more about the grant and what’s next for the team: https://ow.ly/URKJ50YxFFB

AngiotensinII-ATR1 driven stress-erythropoiesis results in increased dysfunctional mitochondria retention in mature RBCs, perpetuating hyperangiotensinemia and sickle cell anemia-associated nephropathy @insight.jci.org
@cincyresearch.bsky.social #Malik
insight.jci.org/articles/vie...

We're proud to see CNN highlight findings from the Cincinnati-based Health Outcomes and Measures of the Environment (HOME) Study, a longitudinal cohort at Cincinnati Children's that has followed families since 2001.

Learn more about the study: scienceblog.cincinnatichildrens.org/how-childhoo...

@babiesresearch.bsky.social @nature.com @npr.org #PediatricResearch #MaternalHealth #NeonatalHealth #ResearchDiscovery

New research looks at mother's antibodies that protect babies from E. coli Cincinnati Children's study reveals that many newborns are protected from serious bacterial infections by antibodies passed from mother before birth.

Dr. Sing Sing Way joined Cincinnati Public Radio's Cincinnati Edition to discuss his new study on how maternal antibodies protect newborns — and what this could mean for preventing serious infections.

🎧Listen here, or wherever you get your podcasts: https://ow.ly/AWbK50YwOP0

#ClinicalResearch #QualityImprovement #HealthcareInnovation #PatientEngagement #RandomizedTrials #TranslationalResearch

Quality Improvement Methods Can Improve Clinical Trial Design - Research Horizons

Randomized trials often struggle with enrollment, retention, and engagement. Our researchers recently published and study that shows how low-cost QI methods can improve all three—without compromising scientific rigor.

What worked? 👇

Parents’ Role in the Triad of Adolescent Shared Decision Making - Research Horizons

Parents, teens & providers form a triad in shared decision making. A new study from Cincinnati Children’s highlights how trust, clear communication & support help families work together as teens take on more healthcare responsibility. Read more on our Science Blog:

Cincinnati Children’s Chosen to Prepare Novel CAR‑T Therapy for Further U.S. Clinical Development - Research Horizons

Our newly expanded Applied Gene and Cell Therapy Center was selected by Tempest Therapeutics to advance a dual-targeting CAR‑T therapy for relapsed/refractory multiple myeloma. Proud of our team advancing next-gen cell therapies! #CellTherapy #GeneTherapy @cincychildrens.bsky.social

Read more:

@babiesresearch.bsky.social @cincychildrens.bsky.social @nature.com #PediatricResearch #NeonatalHealth
#MaternalHealth #InfantImmunity

Mothers’ Exposure to Microbes Protect their Newborn Babies Against Infection - Research Horizons

New research led by our experts finds newborns who develop severe E. coli infection have lower levels of protective antibodies from their mothers. The study, published in Nature, could help identify high-risk infants and guide new prevention strategies. Learn more and see what's next:

Natural maternal immunity protects neonates from Escherichia coli sepsis @cincyresearch.bsky.social @babiesresearch.bsky.social @nature.com
www.nature.com/articles/s41...

This support helps scientists test bold ideas, build new collaborations, and move discoveries closer to cures for children with complex diseases.

@rascalflatts.bsky.social @cincychildrens.bsky.social #ChildHealth #PediatricResearch #Philanthropy #kaleidoscope #WeAreCincyKids

Philanthropy Supports Tomorrow’s Cures - Research Horizons Annual Kaleidoscope event raises $2 million-plus to advance Cincinnati Children's research innovation.

Philanthropy fuels discovery. During our recent Kaleidoscope event, featuring host Cris Collinsworth and a special performance by Rascal Flatts, we received a $2+ million boost from our community of supporters to benefit the Cincinnati Children’s Research Foundation.
Read more: