Science journal cover with a cute rat.

Happy world rat day everyone!
I owe my PhD to this furry friends 🐁

www.science.org/toc/science/...

Hypothalamic endoplasmic reticulum stress drives pubertal precocity due to early-onset obesity in female rodents | PNAS Early-onset obesity, especially in girls, is frequently associated with advanced puberty; a phenomenon bound to increased risk of long-term complic...

Thrilled to see our new paper published in @pnas.org ! 🧬🔬

We uncover a role for hypothalamic ER stress in linking early-onset obesity to precocious puberty in female rodents🐭🧠

Grateful to these fantastic co-authors for making this project possible👩🏼‍🔬🤝🏻👨🏻‍🔬

www.pnas.org/doi/10.1073/...

Thrilled to share that I’ve started as a postdoc fellow in the Navarro Lab at Brigham and Women’s Hospital/Harvard Medical School! Grateful for the opportunity — loving my first days in Boston!🍂🍁

We are waiting for the next meeting to newly experience this exciting and scientific environment. 🧪

During the last two days, 16th IMIBIC Young Investigators Meeting has been celebrated and our young researchers participate sharing amazing works in the endocrinology and reproductive field both in oral and poster communications. Congrats for all these stunning presentations. 🗨️👩🏻‍🔬

The abstract submission deadline for the PANS Workshop in Argentina is now October 10th, 2025! 🎉

Join us in Buenos Aires on December 6th, 2025 for the PANS Workshop “Connecting Neuroendocrinology Across the Americas”.

🔗 Register at paneuroendo.com or through the link in our bio.

Back from the summer break, our team, represented by @manueljpuyer.bsky.social, @silviaddue.bsky.social and @galianorus.bsky.social, attended the @bsneuroendo.bsky.social Congress in Bradford, UK, where they presented their work through posters — a great way to kick off the season! 👩‍💻🔙

Happy to share that last week I defended my 𝗣𝗵𝗗 𝘁𝗵𝗲𝘀𝗶𝘀 🎓 unveiling novel mechanisms in the metabolic control of puberty🧠, led by 𝗗𝗿. 𝗝.𝗠. 𝗖𝗮𝘀𝘁𝗲𝗹𝗹𝗮𝗻𝗼 & 𝗗𝗿. 𝗠. 𝗧𝗲𝗻𝗮-𝗦𝗲𝗺𝗽𝗲𝗿𝗲, conducted at @pubmetts.bsky.social group. Excited for what’s next!

🚨 ¡URGENTE! Buscamos hombres voluntarios para participar como control en un ensayo clínico sobre hipogonadismo. Solo se necesita una muestra de sangre🩸

💉 Rápido, sencillo y vital para la ciencia.
📩 Contáctanos para más info!

We are beyond excited to share that our lab head, Manuel Tena-Sempere, has been selected as the next Editor-in-Chief of Endocrinology, starting January 2026! 📝👨🏻‍💻 An incredible honor and well-deserved recognition!🥳🎉
@endocrinesociety.bsky.social

Thanks so much! Really appreciate the kind words!

Thrilled to share my first first-author publication! 👩🏼‍🔬🔬 Grateful to have worked with such incredible researchers and mentors! @pubmetts.bsky.social

Central lipid sensing pathways contribute to the control of puberty and its alterations in conditions of obesity | American Journal of Physiology-Endocrinology and Metabolism | American Physiological ... Childhood obesity, especially in girls, often correlates with advanced puberty and long-term comorbidities. Among the central circuits controlling energy homeostasis, hypothalamic lipid sensing pathwa...

🚨 Just out! Our latest study uncovers how central lipid sensing shapes puberty timing in obesity 🧠
PUBLISHED and ready to read 👇
journals.physiology.org/doi/abs/10.1...

#Puberty #Obesity #Neuroendocrinology #Metabolism

Investigadores de Córdoba lideran un innovador proyecto europeo para prevenir la obesidad El Imibic y la Universidad colaboran en 'Epr Obes', financiado con cerca de 10 millones de euros por la Comisión Europea

Investigadores de Córdoba lideran un innovador proyecto europeo para prevenir la obesidad https://dozz.es/gnmoo5

Last week #MitoNedWorkshop took place and we couldn't miss the opportunity to share our exciting results elucidating the specific role of Kiss1 neurons in hypogonadism development as well the impact of diet into the gut-brain axis. Brilliant work, Vero and Marina.

Hypothalamic SIRT1-mediated regulation of the hormonal trigger of ovulation and its repression in energy deficit - PubMed Female reproduction is highly sensitive to body energy stores; persistent energy deficit, as seen in anorexia or strenuous exercise, is known to suppress ovulation via ill-defined mechanisms. We repor...

🔬✨ New insights into female reproduction!
Hypothalamic SIRT1 links energy deficits to ovulation by modulating gonadotropin surges via Kiss1 neurons 🧠🌟

📖 Learn more: pubmed.ncbi.nlm.nih.gov/39740742/
#Reproduction #Ovulation #SIRT1 #Kisspeptins

Tena-Sempere’s lab wish you a very merry xmas! #UglyChristmasSweater 🎄🎁

Frontiers | Emerging roles of lipid and metabolic sensing in the neuroendocrine control of body weight and reproduction The hypothalamus lies at the intersection of brain and hormonal mechanisms governing essential bodily functions, including metabolic/body weight homeostasis ...

Interested in lipid and metabolic sensing in the neuroendocrine control of weight and reproduction? 🧠 🍔🤰 Don’t miss out my latest review! @pubmetts.bsky.social

www.frontiersin.org/journals/end...

Hi everyone!! We are the OLD kids on the NEW block, follow us to keep up with the latest news in neuroendocrinology 🤓
Kiss1 for everyone!!!