The @natsmb.nature.com March issue is out! Though always interested in proteostasis, in 2026 we have published and will continue to do so relevant content. Our editorial www.nature.com/articles/s41... recaps why the processes and mechanisms of proteostasis continue to interest us.
Posts by Devanshi Gupta
The E3 ubiquitin ligase mechanism specifying target-directed microRNA degradation (TDMD) is now published! 🎉🍾 We, @bartellab.bsky.social and Schulman lab, describe how 2-RNA factors control protein degradation by recruiting an E3 ligase. @mpibiochem.bsky.social
www.nature.com/articles/s41...
Proteostasis UK Logo Competition
Design our new logo and win registration, UK‑based travel, and accommodation to attend the UK Proteostasis Meeting 2026, 20–21 July at The Francis Crick Institute, London.
See here for more information:
proteostasisuk.co.uk/calls/proteo...
Deadline: 1st May 2026
“.global catastrophe since many incredible programs are not currently being funded. Parasites don’t carry passports. Diseases spread across countries, so being able to survey & address these pathogens in one part of the world benefits public health everywhere.”
www.the-scientist.com/a-low-cost-s...
Excited to announce that FASEB Ignite Career Forum 2026 (preceding FASEB Ubiquitin Mechanisms, Functions, and Therapeutics & Protein Folding in the Cell) is open for registration! Abstract deadline - April 6, 2026
For more details -
events.faseb.org/event/Protei...
events.faseb.org/event/Ubiqui...
Registration is now open for the EMBO Workshop "#Ubiquitin and ubiquitin-like proteins in health and disease" in #Monopoli, Italy, 28 Sep–2 Oct 2026.
Registration deadline: 31 May
Abstract submission deadline: 15 Jun
https://meetings.embo.org/event/26-ubiquitin
#EMBOubiquitin #EMBOevents 🧪
As someone who’s published a couple of two-authored papers:
Yes, they're RARE...
but absolutely possible to conceptualise, execute, draft, and publish with just one or two people.
And when it lands, the sense of ownership and satisfaction is unmatched...
SAVE THE DATE: Ubiquitin & Friends Symposium 2026 on April 29-30 or even better, sign up now: lnkd.in/eEQmaCYT
It takes place at Van Swieten Hall, 1090 Vienna & is organized by the SFB Targeted Protein Degradation (incl. numerous research groups at Vienna BioCenter)
@sfb-tpd-vienna.bsky.social
📣 UK Proteostasis Meeting 2026 – Registration Now Open!
I’m delighted to share that registration is now open for the UK Proteostasis Meeting 2026, hosted by The Francis Crick Institute on 20–21 July 2026
.
Please register here(lnkd.in/ervXMzWN) and through Eventbrite for payment (lnkd.in/eTxqjnQy)
Once a pitch, now a discovery 🔬
Our study provides the first mechanistic explanation of Lis1’s dual role in regulating dynein function is now out in @cp-cellreports.bsky.social
We clarify how Lis1 can both activate and restrain dynein, resolving a longstanding paradox in the field.
XIII-ZOMES & 11th Proteasome Joint Meeting
📍 Montpellier, South of France
📅 27–30 April 2026
www.biolum.cnrs.fr/animation-sc...
Focus on proteasome, COP9 signalosome & eIF3 (PCI) in protein homeostasis/pathology, with great speakers + selected talks.
Info/registration: 13-zomes.sciencesconf.org
All good things come in pairs...
Proud to share our work in @cp-cellreports.bsky.social and @cp-iscience.bsky.social
An end to an era on a high note 🥂
New paper published in @cp-cellreports.bsky.social from the lab of Dr. Subbareddy Maddika on essential regulators of Dynein function.
Read the paper here: sciencedirect.com/science/arti...
@devanshigupta.bsky.social
#dyneinfunction #lish #lissencephaly
Mechanochemistry of Molecular Motors and Filaments. 8-9 May 2026 at University of Warwick.
Calling all #MotorsInQuarantine fans: Please join us for 1.5 days of science on motors and the cytoskeleton as we celebrate the career of Rob Cross. More info and sign-up here: tinyurl.com/mechanochemi... #kinesin #dynein #myosin #microtubules #actin #cytoskeleton
To move or not to move...
That's the question ⁉️
Hard proof of hardwork in PhD is now finally out in @cp-iscience.bsky.social
It looks really pretty 🤩
📢 Call for Abstracts – One Month to Go!
Don’t miss your chance to present at the 51st Lorne Proteins Conference. Share your research, connect with global scientists, and be part of a legacy 51 years strong.
👉 Submit your abstract now: www.lorneproteins.org
#LorneProteins #ProteinScience
Ways for overcoming challenges as a new PI, dealing with bureaucracy, hiring people for the team and ways to keep them.
Such kind of sorts, I think.
📢 Supporting the #nextgeneration of researchers, JCB offers the Hall & Gilula Travel Awards ✈️ that assist #undergraduates, #gradstudents, and early-career #postdocs in attending #CellBio2025 (Dec. 6-10)! Apply by October 17 👉 rupress.org/jcb/pages/al...
Life in academia according to autobiographies of Nobel laureates
Our PhD student will be travelling to Spain to attend the 28th EDRC.
@DBTIndia
#conference #EDRC2025 #Spain
Lots of exciting science is brewing at @grk2243.bsky.social
Just 3 weeks to go until #WUeBI2025! We can‘t wait to welcome you to Würzburg. The full program is now set - check it out and get ready:
➡️ www.ubiquitin-wuerzburg-2025.de ⬅️
I use Google keep. I like the list feature, image attachment option, sync and accessibility on any device.
These are my must-haves
COP9 signalosome and PRMT5 methylosome complexes are essential regulators of Lis1-dynein based transport www.biorxiv.org/content/10.1101/2025.04....
There is absolutely nothing funny about this btw
COP9 signalosome and PRMT5 methylosome complexes are essential regulators of Lis1-dynein based transport www.biorxiv.org/content/10.1101/2025.04....
A dragon is born every time a reviewer responds that they cannot review the paper, but by the way, from the abstract this looks completely flawed.
Thank you so much Samatha for keeping my hopes up 🤞🏽