I'm not looking forward to a future where all the tools are being vibe-rewritten into languages people don't want to learn. Who will maintain all this? The original maintainers won't. It's not the language they were comfortable with. Does the prompter understand the tool well enough?

What’s next: Quarto 2 – Quarto We’ve started working on quarto-dev/q2, a full rewrite of Quarto in Rust.

And another Quarto announcement; I've alluded to it before, but we're making it "official".

We've started work on Quarto 2. The blog post has an overview: quarto.org/docs/blog/po...

We'll share more in future blog posts, but here's what you can expect from the Quarto 2 dev effort:

(1/)

Looking through one of the four windows of the Orion spacecraft, a tiny crescent Earth is illuminated against the blackness of space and grows smaller as the crew journeys closer to the Moon. Part of the window edge is visible; the rest is darkness. [Alt-text slightly revised from ESA/NASA version]

We are so, so small. #Artemis

New tool from the lab...check out Novabrowse: An interactive and customizable tool for interpreting BLAST results in genomic context!
www.biorxiv.org/content/10.6...

Does your favorite gene seems to be missing from your species of interest?

Are you sure?

🧵👇 1/n

Welcome to RustQC Fast quality control tools for sequencing data, written in Rust.

Super excited to be launching two things today: #RustQC 🦀🧬 and rewrites.bio 🚀

I used AI to rewrite 15 RNA-seq QC tools into a single Rust binary (I've never written any Rust). It ended up being over 60x faster. Here's the story 🧵

seqeralabs.github.io/RustQC/

Github now use your interaction with copilot to train their models, unless you disable this feature. Here is how to do:

Go to GitHub Account Settings >
Select Copilot Settings >
In Privacy, Set Allow GitHub to use my data for AI model training to "Disable"

Don't work for free.

Integration of large, complex single-cell datasets with Harmony2 #SingleCell 🧪🧬🖥️
www.biorxiv.org/content/10.64898/2026.03...

Single-cell Long-read Bioinformatics: from Data Generation to Visualisation Hands on training in long‑read single‑cell RNA‑seq, from experimental design to data interpretation

New for 2026, register your interest for our course 'Single-cell long-read bioinformatics: from data generation to visualisation', providing comprehensive end-to-end training on how to perform and analyse data from #longread #singlecell #RNA-seq experiments.

📅 17-19 November 2026

"Here, we present SPAtial Cell Exploration (SPACE), a spatial CRISPR screening platform that integrates whole-transcriptome profiling (~18,000 genes), multiplexed protein detection (~68 markers), and CRISPR perturbation mapping at subcellular resolution"

www.biorxiv.org/content/10.1...

Gorillaz - The Mountain, The Moon Cave and The Sad God YouTube video by Gorillaz

Amazing music, Amazing animation, thanks Gorillaz!
youtu.be/ucRulNQsuYQ?...

Hello, dplyr 1.2.0! Join us with Davis Vaughan to explore new functions! Tuesday, Feb 24 at 12pm ET pos.it/dslab

I'm beyond excited for tomorrow's Data Science Lab with @davisvaughan.bsky.social!

dplyr 1.2.0 is now out. There are many new functions in this release, and you will see them in action, live. You won't want to `filter_out()` this info 😉

Join us, we can't `replace_*` you 🧡 pos.it/dslab

Creating Polished, Branded Documents with Quarto Creating Polished, Branded Documents with Quarto - Isabella Velasquez Resources mentioned in the workshop: * Workshop site: https://bit.ly/rpharma2025-quarto * Exporting Quarto slides to PDF:…

Creating Polished, Branded Documents with Quarto www.youtube.com/watch?v=sVMg... (R/Pharma 2025 #Rstats)

anndataR: converting single-cell data, from R to python and back tomsing1.github.io/blog/posts/a... #Rstats

Pick a License, Not Any License doi.org/10.59350/98n... #Rstats #databs

I feel it quite possible that those relying on AI from the very start may form a different skill set that will accelerate some software, but result in key regressions (without the expertise to address them) in other types. combine-lab.github.io/blog/2026/02... see the caveats section here…

@gmilgram.bsky.social J'utilise la même méthode pour analyser mes séquences ADN. Je réserve une salle de réunion et je les fait défiler sur l'écran. 🤓

Nike et sa chaussure qui booste votre cerveau. Ah ? 😑 YouTube video by G Milgram

Une fois encore, la science se fait piétiner. Heureusement que @gmilgram.bsky.social est la pour la défendre auprès du grand public youtu.be/2jdZbag21xQ?...

#bioinformatics #statistics #memes #bluesci

I'm using #Nexflow almost daily. It is such a time saviour for analysis by suppressing job management. Here is the Hello-Nextflow playlist for those who want to join the Nexflow family. youtube.com/playlist?lis...

Une annonce tonitruante sur un remède au cancer aurait-elle été faite sans vérification de la qualité de la publication ?

Don’t use DataCamp A timeline of transgressions & community response

I just opted out of a workshop with a heavy heart when I learned it's a collab with DataCamp.

No matter what, I'll maintain my boycott — why? Here is a detailed overview: dnlmc.medium.com/dont-use-dat...

There are soooo many other options that value you, the community, and the instructors!

Postdoctoral Researcher (Charpentier Group) | John Innes Centre An exciting opportunity has arisen for a Postdoctoral Researcher to join the Charpentier Group at the John Innes Centre, working on cutting-edge science in the field of plant calcium signalling.

My lab at the JIC is recruiting 3 PDRA:
🔹 Bioinformatics / AI
🔹 Molecular Biology / Genetics
🔹 Proteomics
Programme funded by the Novo Nordisk Foundation.
📅 Closing date: 27 February
Apply via JIC website:
www.jic.ac.uk/vacancies/
Please share with outstanding candidates. 🙏

New tool from @alexsweeten.bsky.social to find and classify all your satellites: "AniAnn's: alignment-free annotation of tandem repeat arrays using fast average nucleotide identity estimates"
📄 www.biorxiv.org/content/10.6...
📦 github.com/marbl/anianns

Emmanuel Macron’s softly-softly approach to Donald Trump is over, it appears. As you'll see below, the Elysée Palace has published a gif of Trump  labelled with one of the US president’s own favourite slurs: “Fake news”.
 1/

European senior diplomats are (indirectly) comparing Donald Trump to Adolf Hitler

[AI bubble bursts] billionaire tech bro: the stupid consumer did not understand it

Opening Bluesky in the morning these days is basically a variation of thinking “what the hell did Trump do AGAIN” and spending a few minutes researching what actually happened

(This is not a criticism of Bluesky, this is a criticism of Trump)

La voiture de la manifestante anti-ICE qui tente de partir. Elle ne fonce pas sur les agents de l'ICE, elle tente de contourner la voiture blanche arrêtée sur la droite mais sans foncer sur les policiers qui sont sur le côté du véhicule, debout. L'un des policiers tire à bout portant.

A Minneapolis l'ICE a tué une manifestante anti-ICE. Elle était dans sa voiture, arrêtée en travers pour bloquer la route. 2 policiers lui disent de sortir, elle refuse et démarre pour s'en aller. Sans rouler vers eux... mais un policier tire à bout portant.
Or, Trump raconte un autre récit. [1]

Top U.S. Universities Are Quietly Removing LGBTQ+ Discrimination Protections From the Ivy League to elite state schools, this list might surprise you

NEW: My research has found that 17 of the 200 highest-ranked U.S. colleges have removed references to gender identity, gender expression, and/or sexual orientation from their nondiscrimination policies. See the full list here: medium.com/prismnpen/to...

Bird feeders have caused a dramatic evolution of California hummingbirds

Evolution doesn’t always take thousands or millions of years. Sometimes it happens right before our eyes.

Such is the case with the Anna’s hummingbird, a species that has undergone a dramatic transformation in a few generations, thanks to the advent of hummingbird feeders: https://scim.ag/3YMuQQu