Dear #spatial #transcriptome scientists, what would be an R based package/pipeline/function suggestion of yours regarding cell/trx niche determination after RCTD deconvolution?

“The Imperial need for authority is so desperate because it is so unnatural. Tyranny requires constant effort. It breaks, it leaks. Authority is brittle. Oppression is the mask of fear.”
#Andor S2 E12

Heavy-heartedly watched season2 episodes 8 and 9 of #Andor. Experiencing such dystopia in our daily lives in Turkiye for a long time is making eveything much heavier...
What a great story-telling, acting, and art in #StarWars Universe, way ahead of the last trilogy f*cked everything.

Dear #microbiome people:
How can I perform beta diversity analysis and permanova testing in R between treatment and control groups for a study where each participant has paired samples collected from two time points?

Another four rejections received today. What a great start to a week 😅

🧠 Microbiome Markers for Epilepsy Subtypes: Our research also revealed that the Eubacterium siraeum group can differentiate between MR and MS epilepsy subtypes.

Key findings include:

🔬 α-Diversity and Age: We found that microbial α-diversity correlates with age in epilepsy patients.

🧒 Differentiating Microbial Profiles in Children: In pediatric epilepsy, Hungatella appears to distinguish epilepsy patients from healthy controls.

Medication‐resistant epilepsy is associated with a unique gut microbiota signature Objective Dysfunction of the microbiota–gut–brain axis is emerging as a new pathogenic mechanism in epilepsy, potentially impacting on medication response and disease outcome. We investigated the co...

Our latest study entitled "Medication-resistant epilepsy is associated with a unique gut microbiota signature" where I have been one of the co-first-authors with Antonella Riva and Greta Volpedo from Genoa.

onlinelibrary.wiley.com/doi/full/10....

Still seeking jobs in Bioinformatics.
Experienced in 16S seq, shotgun metagenomics, and bulk RNAseq analysis. Skilled in R for multi-omics integration, statistics, and visualization. Currently expanding expertise in single-cell/spatial omics and Nextflow pipeline management.
#Bioinformatics

Closing the day with nine new applications 🤞

#bioinformatics #multiomics #jobsearch #postdoc

Entering to the last week of my full time work ar CosmosID. Feeling extra emotional 🥹

“Good science ends when you become more attached to your solution
than to the problem.”
Me - 2018

Still seeking jobs in Bioinformatics.
Experienced in 16S seq, shotgun metagenomics, and bulk RNAseq analysis. Skilled in R for multi-omics integration, statistics, and visualization. Currently expanding expertise in single-cell/spatial omics and Nextflow pipeline management.
#Bioinformatics

Another day of feeling worthless and pathetic, will fade away tomorrow.

#LifeWithAnxiety

Happy International Women & Girls in Science Day 2025 #WomenInScience #womeninSTEM #IDWGS

This is an opportunity to point out that there are 364 other days in the year to talk about, highlight and celebrate Women in Science.

CDC datasets uploaded before January 28th, 2025 by Centers for Disease Control and Prevention Topics cdc, government, united states, dataset, archive Language English Item Size 98.5G An archive of all CDC datasets uploaded to https://data.cdc.gov/browse before January 28th, 2025. Excludes corrupt datasets and data not publicly accessible.

The entire archive of all CDC datasets uploaded before January 28th, 2025 has been backed up on Internet Archive.

Incredible work everyone. Science will never be silenced!

Use the Human Microbiome Compendium data!

We made the data and code available, & created a website and R package to navigate the compendium. Links:

- Website: microbiomap.org

- Data: zenodo.org/records/1373...

- R package: blekhmanlab.github.io/MicroBioMap/

- Code: github.com/blekhmanlab/...

Loving #stackoverflow community. ChatGPT can never (LoL) replace it.
#bioinformatics #R #analysis #joy

Hope to move from #2 to @1 for myself :)

A one-panel comic by Glauco Villas Boas. A group of people stand against the corner of a wall. One reaches around the corner and uses a long stick to push open a door labeled 2025.

This comic gets shared every year with the date changed. It is by Brazilian cartoonist Glauco Villas Boas (1957-2010).

Happy Friday!

Would love to be involved, if possible

I'm happy to announce our next computational genomics course for 2025 🖥️ 🧬 🧪. The deadline for application is January 30th 2025. We will cover:
- AI-assisted data analysis
- Spatial omics analysis
- Multi-omics data analysis.
More info is here: bioinformatics.mdc-berlin.de/compgen/2025/

What about dealing with a 35 years old myself refusing to leave bad and now suffering reflux 🙈😂

Very excited (and a bit nervous) to announce that I will be hiring two Postdocs for my new group(!) in Copenhagen to study the Neanderthal and Denisovan DNA which survives in present-day humans. Retweet will be much appreciated :)

Link for application:
candidate.hr-manager.net/ApplicationI...

Thanks a ton 🙏

I have been looking for options in Europe