Our findings suggest that circadian misalignment precedes overt muscle wasting and is closely linked to the onset of metabolic inflexibility.
Excited about what this could mean for understanding early drivers of cachexia and looking forward to sharing more with the scientific community soon!
Posts by Francielly Morena
Had a fantastic time sharing my postdoctoral work with an incredible community of scientists and colleagues at the Myology Institute.
Using the PER2::LUC circadian reporter mouse, we mapped the temporal progression of circadian disruption in the experimental pancreatic KPC model.
Our latest WCX Quarterly Newsletter is out!
This issue is all about community + science:
β new cachexia research
β celebrating trainees & early-career wins
β upcoming journal club
β Save the date: featured talk with Dr. Grandis
WCX, building a space where science and support go hand in hand π
Want to be inspired by and interact with great scientists? Thereβs still time to register for @cancercachexia.bsky.social WCX initiative Stories and Science with Dr. Sarah Kolitz.
Tomorrow, Jan 20th at 12EST.
See you there!
Link to register: us02web.zoom.us/webinar/regi...
Ready for some Stories and Science?
Join us on January 20th!
Register for the Stories & Science here:
us02web.zoom.us/webinar/regi...
@cancercachexia.bsky.social
@aneedasgupta.bsky.social
@snoke-phd.bsky.social
@parnesonwissink.bsky.social
@brittcounts.bsky.social
@debi-mukh.bsky.social
@aneedasgupta.bsky.social @snoke-phd.bsky.social @brittcounts.bsky.social @parnesonwissink.bsky.social @debi-mukh.bsky.social
β¨ WCX Quarterly Newsletter is out! β¨ @cancercachexia.bsky.social
New leadership, community announcements, and fresh science β plus Stories & Science in January with Dr. Kolitz.
π Newsletter, links to publications & register for the Stories and Science:
www.cancercachexiasociety.org/assets/2025/...
Studying metabolism? Pay attention to time of day Nice collaborative review led by Satchin Panda www.nature.com/articles/s42...
Great first day of the Muscle Biology Meeting! Come chat with me about circadian clocks & muscle atrophy over at poster 101 tomorrowβ°πͺπ½
Updated version of our preprint is now live! In addition to our prior data, we conducted a 2ndary analysis of CT-based body comp collected from the National Lung Screening Trial. We found that there are body composition changes prior to cancer diagnosis.
www.biorxiv.org/content/10.1...
Thank you, Brian!!
π π¨ @fmorena.bsky.social et al use transcriptional analysis to clarify model-specific cancer cachexiaβs complexity. Key finding: Osmr emerges as a universal candidate and the circadian clock genes are impacted. Details π journals.physiology.org/doi/abs/10.1...
#Cancer #Cachexia #Circadian #Muscle
It was a pleasure being interviewed by the Women in Cachexia Initiative for their quarterly newsletter spotlight!@cancercachexia.bsky.social
Tremendous initiative with great events, information, and collaboration opportunities. Thank you WCX team!
www.cancercachexiasociety.org/assets/2024/...
Cannot wait!
I made a starter pack for those involved in cachexia encompassing every aspect :research, teaching, clinical, caregiver, patient.
Tagging a few people to spread the word:
@marcusgon.bsky.social
@fmorena.bsky.social
@snoke-phd.bsky.social
go.bsky.app/PNfvbUm