Microbial interactions affect the tempo and mode of antibiotic resistance evolution bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution

New preprint from the lab:
Microbial interactions affect the tempo and mode of antibiotic resistance evolution. www.biorxiv.org/content/10.1...
#microsky

I'm recruiting a Research Technician to work on plasmid transmission and antimicrobial resistance in St Andrews, to start in October. Deadline for applications is 19 June. Please share!
www.vacancies.st-andrews.ac.uk/Vacancies/W/...

Loretta Mugo - my first Insect doctors Phd - just passed her viva at University of Tours with double degree at Exeter - congratulations

In Beijing hosted by Changlong Shu. He is researching how to use white grubs to process crop residues that are currently incinerated. The frass can go back to land to boost organic carbon while the bugs can be used for animal feed.

When does antimicrobial resistance increase bacterial fitness? Effects of dosing, social interactions, and frequency dependence on the benefits of AmpC β-lactamases in broth, biofilms, and a gut infec... Abstract. One of the longstanding puzzles of antimicrobial resistance is why the frequency of resistance persists at intermediate levels. Theoretical expla

I spent a long time developing a good gut infection model in insects to test AMR theory. My excellent ex student Elissa has just had this test of cooperative detoxification published using this model as well as biofuels etc. There’s lots in here!

academic.oup.com/evlett/advan...

Varying phylogenetic signal to four bacterial pathogens across species of Drosophilidae bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution

Congrats Hongbo! 1st PhD paper with @blongdon.bsky.social & @benraymond.bsky.social.

#Pathogen host shift modelling w/ #bacteria infections across a 36-species panel. Great dataset and analysis to start teasing apart the rules of host*pathogen dynamics across species.

#immunosky #Drosophila

Nice one

I think it’s particularly cool because a classic critique of social evolution is that experiments use toy traits in carefully selected & simplified conditions. Here we
applied a selection regime in vivo designed to promote sociality and watched to see what traits would emerge…sporulation was key!

Hello Bluesky ! Still in process of abandoning X so here is an opportunity to promote Zoltan’s excellence work on multilevel selection in a fungal pathogen

doi.org/10.1371/jour...
Our new study investigates the evolution of virulence of a fungal entomopathogen in vivo. Through a lens of evolutionary theory, we explore multi-level selection, revealing conflicts and potential for improving biocontrol traits! @benraymond.bsky.social