When I feel that overwhelmy stuff coming on I go full 🤖 Probably crying would be healthier but I forgot how

great article in @quantamagazine.bsky.social by natalie wolchover on the bacterial flagellum and proton motive force. alas, I missed this great model on what happens to the stators during gear-shifting. see it in STC:
smallthingsconsidered.blog/schaechter/2...
#MicroSky

I've had this pumpkin since Oct & it still seems happy

Don't be shy to take on a little two-week side project. These five months will be the most precious three years of your academic journey.

chemical mapping generated human single-base-pair–resolution nucleosome positioning maps during interphase and metaphase, revealing widespread nucleosome repositioning at gene regulatory regions across the cell cycle ➡️ link.springer.com/article/10.1...

My super department @warwicklifesci.bsky.social is hiring 6 assistant profs in the wake of recent retirements. We're looking for people in microbiology/infection, cellular disease / immunity; environmental biology; and plant/crop science. #MicroSky warwick-careers.tal.net/vx/lang-en-G...

cAMP triggers the turbo for swimming speed in 𝘝𝘪𝘣𝘳𝘪𝘰 𝘤𝘩𝘰𝘭𝘦𝘳𝘢𝘦 O1 AJ10 via its light-responsive adenylate cyclase, a cyaA variant in some but not all 𝘝𝘪𝘣𝘳𝘪𝘰 𝘤𝘩𝘰𝘭𝘦𝘳𝘢𝘦 strains/isolates (of course, also CRP is involved)

#MicroSky 🙏for the shoutout @cyrilpedia.bsky.social

A diagram showing that 24 annually funded grants becomes only 15 funded grants if 50% of the funds for competitive grants are used for multi-year funding.

I was preparing for a talk I gave last evening to a lay audience and came up with this graphic to explain multi-year funding and why it leads to fewer competitive awards and funding investigators and projects.

6/8

So many academic departments make up the fabric of a university. They teach the courses for their majors but also for students in other majors who either have to or want to take.

They're each part of what it means to offer well-rounded educational opportunities.

This is all a loss

How did you get better at it (besides better screens). I can read the thing, but I can't remember what I read later unless I touched paper

I have to print things I need to mentally digest. Unable to convert to screen digestion. Anyone else have this problem?

Very proud of this work and all the efforts from my team and collaborators on this! You can now use DGRs for in vivo targeted hypermutagenesis in E. coli. We also included some early proof of concept in Yeast thanks to @seth-shipman.bsky.social !

@heatherfeaga.bsky.social
Yeaaaaaah! 🥳

We recently did an accidental synthetic lethal screen b/c strain 2158 was streaked instead of 2518

Brief fun survey from Jessica, Andrew & myself:

If you are a faculty member, research scientist, postdoc, or senior Ph.D. student in any area of science, please take five minutes and fill it out. We’ll share the results widely along with some reflections.

docs.google.com/forms/d/e/1F...

Holy hell, I felt like I was sacrificing my children only being able to pick 6

If you have a snack attack on a moon mission, is that allowed?

Gary Larson perhaps portrayed this best with his school for the gifted cartoon

And there is additional strong evidence that Shingles vaccine delays or reduces dementia. Everyone eligible should get this vaccine

The next International Conference on Gram-Positive Bacteria will take place between 29 June – 2 July 2027 in Ljubljana, Slovenia.

#subtiwiki

Excited to share our new paper out today in @science.org 🎉

We show that HGT via natural competence drives diversification of chromosomal integrons in V. cholerae 🤩

Below a 🧵 on key findings incl. background on natural competence in V. cholerae 1/
#microsky #phagesky
www.science.org/doi/10.1126/...

😱 Wow: Competence-mediated DNA uptake diversifies Vibrio cholerae sedentary chromosomal integrons:

👇

www.science.org/doi/10.1126/...

@science.org #vibrio

Two panel comic. Panel 1: a digital kiosk at the entrance of a parking garage with a dispensed ticket. The screen display reads: PLEASE TAKE TICKET BELOW. Panel 2: a T-Rex is sticking its little arm out the window of its partially opened car door, trying to reach the ticket.

Very sorry to hear. Thank you for honoring his memory

We are recruiting postdocs to work on antimicrobial resistance and bacterial cell envelope biology. PLEASE SHARE.

I will report back in 2 wks. You know how attention spans work

You can also submit your one-day-potentially- foundational-science to your favorite trusted society journal, save ~75% on publication fees, & it will still be available to anyone who can read. Just saying
www.nature.com/articles/s41...

CSR to continue the one-third triage cutoff for NIH grant review Some non-public information points to CSR continuing to triage grant applications at about the 33% line, instead of the traditional 50% line. This was originally put in place for the re-scheduled F…

CSR to continue the one-third triage cutoff for NIH grant review drugmonkey.wordpress.com/2026/04/06/c...

Shoe taped to door jam

Strategy #lostcount to get my kids to put their shoes away

Local peptidoglycan composition defines division site selection in Streptococcus pneumoniae Nature Microbiology, Published online: 07 April 2026; doi:10.1038/s41564-026-02322-6Sequential peptidoglycan carboxylase activity of DacA and DacB generates a local peptidoglycan signature that recruits MapZ and establishes the division site at the Streptococcus pneumoniae cell equator.

Out Now! Local peptidoglycan composition defines division site selection in Streptococcus pneumoniae #MicroSky