✅ Registration is now open for SENESCEL 2026 (Sept 16-18, Salamanca, Spain).
Enjoy a fantastic lineup of international speakers on aging and cellular senescence at this beautiful city.
senescel2026.org/registration/

In this study, we uncover the senolytic mechanism of conjugated polyunsaturated fatty acids (PUFAs), specifically α eleostearic acid (α-ESA), demonstrating that these compounds eliminate senescent cells by inducing ferroptosis, rather than classical programmed cell death pathways.

yICSA Webinar Series: Osama Elsallabi YouTube video by ICSA main

youtu.be/cbqrqdFGsN8?...

Really grateful for the chance to share my journey across Europe and the U.S.
looking forward to it!

#ICSA #cellularsenescence #agingresearch #academia #senolytics #geroscience

Had an amazing time at SenesceL 2025 in Barcelona! Great science, great talks, and so nice seeing familiar faces again. Can’t wait for next year. Big thanks to the organizers! @senescel.org

Elastin-derived extracellular matrix fragments drive aging through innate immune activation @nataging.nature.com
www.nature.com/articles/s43...

It was great to be at #ICSA2025Rome grateful to present my research & connect with brilliant scientists. Thanks to MarcoDeMaria, @martakova.bsky.social & Fabrizio D’Adda di Fagagna for the outstanding organization! @icsasenescence.bsky.social @yicsac.bsky.social

Highlights from yICSA at #ICSA2025Rome 🌍✨
✔️Networking Social Event 🤝
✔️Special Session with career insights from @dimiccolab.bsky.social & @narita-lab.bsky.social 🙌
Thank you to everyone who joined us!
#yICSA #Senescence #ECR

Excited to dive into fascinating science on cellular senescence! @yicsac.bsky.social @icsasenescence.bsky.social
#CellularSenescence #Aging #ICSA2025 #yICSA”

Mitochondrial innate immune signaling in skeletal muscle adaptation to exercise Exercise-induced inflammation is regarded as a response to muscle damage from mechanical stress, but controlled immune signaling can be beneficial by promoting metabolic adaptation which, for example,...

“NIH researchers found that exercise triggers mitochondrial DNA release in muscle, activating immune pathways that boost fat-burning fibers and fight obesity—but this same response may worsen fatigue in long COVID and #ME/CFS through immune overactivation.” www.cell.com/trends/endoc...

Mindblowing!!!

Are you interested in joning our lab to work on #CellSenescence? You could apply for a MSCA fellowship, the call is open: ec.europa.eu/info/funding...
Get in touch!

🪰 The next step is to carry out a more extensive search in the drosophila fly genome.

In the long-term, this knowledge could be used to increase the success rate of assisted reproduction treatments and to develop drugs to tackle aneuploidy, which is a characteristic of many tumours.

Identification of lipid senolytics targeting senescent cells through ferroptosis induction Cellular senescence is a key driver of the aging process and contributes to tissue dysfunction and age-related pathologies. Senolytics have emerged as a promising therapeutic intervention to extend he...

www.biorxiv.org/lookup/doi/1...

Development of novel flavonoid senolytics through phenotypic drug screening and drug design Accumulation of senescent cells drives aging and age-related diseases. Senolytics, which selectively kill senescent cells, offer a promising approach for treating many age-related diseases. Using a se...

www.biorxiv.org/content/10.1...

Fucoidans are senotherapeutics that enhance SIRT6-dependent DNA repair Aging is marked by the accumulation of senescent cells (SnCs), which contribute to tissue dysfunction and age-related diseases. Senotherapeutics, including senolytics which specifically induce lysis o...

doi.org/10.1101/2025...

Loved the mix of science, good conversations, and familiar faces. Already looking forward to the next one!

#PhDLife #CellularSenescence #KarolinskaInstitute #yICSA #ResearchCommunity #Gratitude

It was really special to meet Federico Pieatrocola again, the one who first got me interested in senescence. Super grateful for that early spark. And big thanks to Francesca Castoldi for being such a great teacher when it came to lab techniques!

Had the pleasure of presenting my PhD research at the yICSA Symposium at the Karolinska Institute! It was a great experience to share my work on cellular senescence and connect with so many scientists.

🚨 Calling senescence researchers!
Applications are open for the #ICSARome2025
@icsasenescence.bsky.social & @yicsac.bsky.social
Travel Fellowships 🌍✈️
Need-based & merit-based awards available!
🗓️ Deadline: May 15