Percentage of PCs undergoing cell proliferation is not changed but the percentage of PCs undergoing apoptosis is increased upon CDK1 and PLK1 inhibition. (A) PCs were immunolabeled with the Sp1 antibody shown in red. Dividing cells at the gastrula stage are shown in green and DNA is shown in blue. Scale bar = 50 μm. Orthogonal projection of images shown.

#DBfeature

Proteins involved in cell division have broad tissue-specific functions in sea urchin development

By Jessica Benito, Elizabeth McCulla, Raisa Sumaiya, Jia Song

tinyurl.com/554jhd6h

Model of N/C as a universal clock of ZGA

This finding provides broad comparative support for the longstanding hypothesis that the nuclear-to-cytoplasmic (N/C) ratio acts as a timer of genome activation. Moreover, this scaling accurately predicts ZGA timing across diverse animals from genome size and egg volume of a species alone. 8/15

These images show live embryos of animals (jellyfish, crustacean, worm, sea urchin, sea squirt, beetle) and one of animals closest single-celled relatives. They were captured taking advantage of fluorescent proteins localised on the outer membrane of cells, allowing us to observe cell outlines. 1/9

New preprint out! We show how cellular nematic order can be harnessed to program tissue-wide force fields and guide 3D shape transformations.

The tissue morphogenesis logic, now engineered into living, programmable materials.

www.biorxiv.org/content/10.1...

#ActiveMatter #TissueEngineering

A series of spontaneously blinking dyes for super-resolution microscopy - Nature Methods A series of spontaneously blinking dyes in the far-red range facilitate single-molecule localization microscopy. These dyes vary in their blinking properties and can be matched to the applications and...

Out in @natmethods.nature.com: More dyes. They work. Quite well. And blink. Pick the one that fits your target, your technique, and your labeling density. With too many collaborators and institutes to list, but anchored at @hhmijanelia.bsky.social www.nature.com/articles/s41...

Examples of the new model organism shirts for sale on the SDB merchandise website

Excited to share that @socdevbio.bsky.social has a new and improved merch store! Rep your fav model organism in one of the Society’s new original designs 🤗 sdb-official-merch.printify.me

Two great talks coming up this Thursday at VGZT!

🗓️ Thursday, April 16th
⏰ 9:30 PDT / 12:30 EDT / 17:30 BST / 18:30 CEST

Our speakers are
👉 Meng Zhu (@zhumeng123.bsky.social)
👉 Pulin Li (on X: @Pulin_Li)

See you on Thursday! 👋

Grateful for my undergrads 🥰

RNA-specific local translation is patterned by condensates for multinucleate cell growth - Nature Cell Biology Geisterfer, Jalihal et al. show spatially distinct effects of Whi3 condensates on target translation in Ashbya syncytia. In vitro, translation is enriched at condensate–solute interfaces but repressed...

www.nature.com/articles/s41...

Would you like to learn about ✨ #Nudibranch 🐌 🌊 regeneration✨ and the evolution of ✨ ✨ #musculoskeletal 🍖 development in avian models 🐣 ✨ ✨ ? Join us this next Monday 1pm ET for our first @evodevopanam.bsky.social #EvoDevoMondays! It’s open to all registrants 🩷. Link 🔗 👇

🗓️Key dates:
Early-bird deadline – 8 May 2026
Abstract deadline – 12 June 2026
Final registration deadline – 24 July 2026

🎤An amazing line up of speakers and organised by some of your fav dev bio scientist ;)

@wellcometrust.bsky.social @bsdb.bsky.social @biologists.bsky.social

‼️The registration for the Development Journal Meeting 2026 - Human Development: Stem Cells, Models, Embryos is now open. This year marks a collaboration between @dev-journal.bsky.social and the Human Developmental Biology Initiative consortium.
www.biologists.com/meetings/dev...

14th Structural Birth Defects Meeting flyer Children's Hospital of Philadelphia; Philadelphia | September 21-23 2026; Abstract Deadline June 22; Photo of Children's Hospital of Philadelphia; Abstracts & Registration Open May 1; Keynote Speakers: Erica E. Davis, PhD, Ann & Robert H. Lurie Children's Hospital of Chicago, Northwestern University; Jeremy Reiter, MD, PhD, University of California, San Francisco

Save the Date! The 14th Structural Birth Defects Meeting will be September 21-23 @childrensphila.bsky.social Keynotes: Erica E. Davis @luriechildrens.bsky.social @feinberg.northwestern.edu & Jeremy Reiter @reitergroup.bsky.social at UC San Francisco. Abstracts & registration open May 1. #14thSBD

New preprint @cxqiu.bsky.social @jshendure.bsky.social ! Can we learn regulatory grammars of human cell types — by training on mouse development and transferring across 241 mammalian genomes? Introducing STEAM & a whole-organism scATAC-seq atlas from E10 to birth.
www.biorxiv.org/content/10.6...

Humm enhancer power! www.nature.com/articles/s41...

Wuau beautiful images

Mapping the maternal–fetal interface through pregnancy in high resolution @nature.com
www.nature.com/articles/d41...
www.nature.com/articles/s41...

Thank you for the shoutout @drstarbird.bsky.social. We are both on the ballot and you can vote for 3 Council members in addition to other leadership positions. If you are an @ascbiology.bsky.social member, find that email and please vote before April 30th! 🤩🗳️

Primary cilia and BBS4 are required for postnatal pituitary development Primary cilia orchestrate several signaling pathways, and their disruption results in pleiotropic disorders called ciliopathies. Bardet-Beidl syndrome…

Excited to have my first senior author publication out in the world! An awesome collab between myself in @reitergroup.bsky.social's lab and the Berbari lab at IU. We found primary cilia are necessary for postnatal pituitary development. 1/n.

www.sciencedirect.com/science/arti...

Join us this Friday at 3pm ET for another #SDBPostdocSeminar featuring @mads100tist.bsky.social and Yiqun Wang, who will be presenting their awesome research! 🐟 🐌
Martha Echevarria-Andino and I will be moderating 🌼

Two decades of induced pluripotent stem cell research: From discovery to diverse applications Since the discovery of induced pluripotent stem cells (iPSCs) 20 years ago, iPSC technology has transformed stem cell research and regenerative medicine. This perspective reviews key advances in repro...

🚨 NEW 🚨

"Two decades of induced pluripotent stem cell research: From discovery to diverse applications" by Shinya Yamanaka

Catch up on Development presents… webinar on neural development - the Node Our February webinar featured three early-career researchers studying neural development. Here, we share the talks from Joaquín Navajas Acedo (University of Basel) and Carlo Donato Caiaffa (Universida...

Catch up on Development presents… webinar on neural development

Our February webinar featured early-career researchers studying neural development. Here, we share the talks from Joaquín Navajas Acedo @mads100tist.bsky.social & Carlo Donato Caiaffa. #DevPres

thenode.biologists.com/catch-up-on-...

I illustrated my way through the @bsdb.bsky.social Spring Meeting a couple weeks ago - here's my illustrated summary of the conference! I sketched (almost) all the speakers and glimpses of the science that made it such a great few days.

photo of company staff

Paid 12-month internship: Communications Officer. We have an exciting opportunity for someone looking to take their first step into a science communication or publishing role. Based Cambridge, UK (& wfh). See the full role description for further details at biologists.com/wp-content/u...

PREPRINT ALERT !!!
Excited to share our #reptile #embryo cryopreservation method optimised on peri-gastrulation veiled chameleon embryos! This lays the foundation for functional studies & reptile #conservation efforts!
#devbio #squamates #evodevo

www.biorxiv.org/content/bior...

If you know a graduating undergraduate looking for the chance to spend 1-2 years in a lab before graduate school, we're hiring! Our lab explores morphogenesis, defining how the cell adhesion & cytoskeletal machinery work together to allow cells to change shape & move tarheels.live/peiferlab/ 1/n RT

Linked in post from Sarah Bray The Company of Biologists (known for its 5 journals, Development, Journal of Cell Science, Journal of Experimental Biology, Disease Models and Mechanisms, Biology Open, as well as its charitable activities) is looking to appoint a new CEO. An opportunity to guide the next chapter! More information here:

The Company of Biologists @biologists.bsky.social has a more than 100 year history of supporting science through its journals, meetings, and fellowships. Help lead it into its second century! pls share
www.inspiredselection.com/jobs/jo00000...

Unraveling the genetic landscape and admixture dynamics of urban populations across Peru - Communications Biology Genomic analysis of Peruvians populations reveals how admixture and recent migrations shaped genetic diversity, fine-scale structure, and sex-biased ancestry in the context of urban areas.

Despite broad "mestizo" classifications, urban Peruvians retain strong Andean and Aymara genetic continuity, inherited primarily through maternal lineages due to colonial dynamics. 😍😍😍 share.google/RXHaOCZElvDp...