New publication out in Intensive Care Medicine! We review the challenges & advances in managing atrial fibrillation in critical illness, and outline key gaps for future research.
Read it here: doi.org/10.1007/s001...
#ICU #AFib #CriticalCare

@ortegamartorell.bsky.social @ivanolier.bsky.social @ingeborgwelters.bsky.social

In Lund, Sweden 🇸🇪 for the TARGET meeting — advancing AI-driven virtual twins 🤖 to fight AF ❤️ and stroke 🧠 across Europe 🇪🇺

#TARGETproject #DigitalHealth #AF #EUresearch

@nhsuhlg-ri.bsky.social @target-horizoneu.bsky.social @liverpooluni.bsky.social

Opening slide regarding Haemodynamic effects of Prone Positioning by Prof X. Monnet

Infographic describing potential outcomes of prone positioning g on the cardiovascular system

Four keys messages on the impact of prone positioning on patient Haemodynamics

Prof Xavier Monnet addresses the HD effects of prone positioning.

Great take homes about the risk of the waterfall effect and the use of Trendelenburg position in the prone patient to predict fluid responsiveness.

Linked paper below

#ISICEM25
#EMIMCC

ccforum.biomedcentral.com/articles/10....

#ISICEM25 | Always fascinating to hear @MichardFrederic discuss the future of bedside screens 🖥️🔍

📊 Evolution to visual decision support tools
🔹 Turning data into knowledge
⚡ Faster & more accurate detection of abnormalities
🧠 Improving situation awareness & reducing cognitive workload

Absolutely thrilled that @liverpooluni.bsky.social 4th year medical student Jessica who undertook her MRes with us at NHS University Hospitals of Liverpool Group has won an award for her poster at #isicem25 #isicem ISICEM. Absolutely bossing it! 👊🏻🤗 well done Jessica! 👊🏻

@nhsuhlg-ri.bsky.social

Visual Abstract. Inhaled Sedation in Acute Respiratory Distress Syndrome

Among patients with moderate to severe ARDS, inhaled sedation with sevoflurane resulted in fewer ventilator-free days at day 28 and lower 90-day survival than sedation with propofol. https://ja.ma/4kxDZGm #ISICEM25

Prof. Julia Wendon finishing her talk on acute on chronic liver failure (ACLF) and encouraging hepatology sustaining behaviours.

The liver IS evil.
Is does needs exercise

The day ends with a phenomenal talk from one of my favourite hepatologists - Prof Julia Wendon.

ACLF… a difficult topic that we all should know more about.

Prognosis is everything.
#ISICEM25
#EMIMCC

Now @pirracchior presenting the OVISS Reinforcement Learning Study: Optimal Vasopressin Initiation in Septic
Shock

@ISICEM.bsky.social #ISICEM25

Results of the #SESARtrial:

Among patients with moderate/severe ARDS, inhaled sedation with sevoflurane resulted in
- fewer ventilator-free days at day 28
- lower 90-day survival
than sedation with propofol.

Now published in JAMA jamanetwork.com/journals/ja...

@isicem.bsky.social #ISICEM25

Optimal Vasopressin Initiation in Septic Shock This multicenter study uses reinforcement learning to examine the treatment implications of a vasopressin initiation rule developed to improve short-term and hospital outcomes in critically ill adults...

At #ISICEM

Fodder for the evening run is gathering.

Not least the OVISS study looking at a reinforcement learning tool for the optimal timing of vasopressin introduction.

jamanetwork.com/journals/jam...

@isicem.bsky.social is renowned for its full, high-quality scientific program.
Watch now Prof. Fabio Taccone's recommendations & start crafting your personalized learning journey today!
More sessions on isicem.org/1/ProgrammeI...

#criticalcare #intensivecare #emergencymedicine

Image shows article on website.

"The sparseness of formal regulation contrasts starkly with AI’s potential to cause harm." This Viewpoint examines prospects for populating the regulatory landscape for health and health care AI in the coming years. https://ja.ma/429LY54

This is horrible to post, but I may as well post it. We are essentially shutting down research operations in my group, which is focused on treatments for pediatric brain cancer. I’m a well funded investigator, and there’s no choice. Science can’t function without the stability of NIH

A Vaccine For Pancreatic Cancer Continues To Show Promise In a small trial, nearly half of pancreatic cancer patients who received an mRNA vaccine for the disease had no relapse three years later.

In a small trial, nearly half of pancreatic cancer patients who received an mRNA vaccine had no signs of relapse after three years.

Dr. Vinod Balachandran from @mskcancercenter.bsky.social joins us to discuss the results and what they could mean for cancer treatment.

🩺🫀 Exciting news! 🫀🩺

Thank you, Isansys Lifecare, for delivering our next batch of wireless patient monitoring systems for the WARD 24/7 substudy!

We’re using AI & wireless monitoring to improve patient care & save lives.

#AIinHealthcare #WirelessMonitoring #Research #AI

@nhsuhlg-ri.bsky.social

Disappointing decision whatever the underlying reasons, given that Liverpool's future economic growth is centred on Health and Life Sciences development.

Me in a hospital bed wearing one of those standard NHS hospital gowns preparing for a mastectomy

It's World Cancer Day and 10 years ago this year I was diagnosed with breast cancer. I can't believe it was a decade ago

This is me in hospital waiting to have a mastectomy. I'm smiling but god I was so anxious, so worried I wouldn't wake up from the anaesthetic

🧵

Signalling pathways, cytokine axes and possible therapeutic interventions for managing CAR-T cell inflammatory toxicity.

#Medsky🧪 #IDSky #Immunosky #pharmasky #publichealth This Review discusses management of safety issues for #CARTcell therapies : #cytokine release syndrome, as well as druggable targets & cellular engineering strategies to develop safer #CART cells

www.nature.com/articles/s41...

🚨🚨We’re so excited to be back podding today!!

Listen now to the first episode in our new Guidelines Series. We’re starting with the Asthma GINA guidelines and today talking about diagnosis, assessment, and phenotyping

www.pulmpeeps.com/2025/02/04/9...

And submental muscle recruitment increases during expiratory loading tasks

pubmed.ncbi.nlm.nih.gov/17294298/

Although post extubation dysphagia is clearly multi factorial, could training of the submental muscles after extubation improve swallowing?

Effects of Expiratory Muscle Strength Training on Swallowing in Survivors of Critical Illness: A Protocol for a Systematic Review and Meta‐Analysis Background and Aims Post Extubation Dysphagia (PED) is a common consequence of mechanical ventilation. Muscular weakness and atrophy are potential causes. Expiratory Muscle Strength Training (EMST) ...

Expiratory muscle strength training (EMST) has some evidence for improving swallowing in several disease states

But what about after extubation in intensive care? Can EMST improve post extubation dysphagia?

Our SR protocol, published today #critcare

onlinelibrary.wiley.com/doi/full/10....

Effects of Expiratory Muscle Strength Training on Swallowing in Survivors of Critical Illness: A Protocol for a Systematic Review and Meta‐Analysis Background and Aims Post Extubation Dysphagia (PED) is a common consequence of mechanical ventilation. Muscular weakness and atrophy are potential causes. Expiratory Muscle Strength Training (EMST) ...

🫁 Can breathing training help ICU patients swallow again?

💡 41% of ICU patients struggle with swallowing after ventilation. This review explores Expiratory Muscle Strength Training (EMST)—a technique that strengthens breathing muscles 💪 to aid recovery.

#medsky #icu #criticalcare #recovery

Screening performance and characteristics of breast cancer detected in the Mammography Screening with Artificial Intelligence trial (MASAI): a randomised, controlled, parallel-group, non-inferiority, ... The findings suggest that AI contributes to the early detection of clinically relevant breast cancer and reduces screen-reading workload without increasing false positives.

New: The largest medical A.I. randomized controlled trial yet performed, enrolling >100,000 women undergoing mammography screening
The use of AI led to 29% higher detection of cancer, no increase of false positives, and reduced workload compared with radiologists w/o AI thelancet.com/journals/lan...

Stromatolites xkcd.com/3046

@liverpoolccs.bsky.social @nhsuhlg-ri.bsky.social @liverpooluni.bsky.social @ljmuofficial.bsky.social

Sage Journals: Discover world-class research Subscription and open access journals from Sage, the world's leading independent academic publisher.

🚑 Can AI predict pneumonia severity? A study finds ML models show promise but need better validation. Some outperform CURB-65, but practical barriers remain. Future focus: clinical validation, integration & transparency. AI in healthcare is evolving—will it transform pneumonia care? #AI #Healthcare

The NHS treats research as a hobby rather than a properly remunerated part of a clinician’s work. www.ukri.org/news/report-...

#sepsis @nhsuhlg-ri.bsky.social

One of my kitchen utensils seems to be playing classical music.

I think it’s the Chopin board.

#dadjokes