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a man in a suit and tie stands at a podium and says " fool me you can t get fooled again " ALT: a man in a suit and tie stands at a podium and says " fool me you can t get fooled again "
3 hours ago 1 0 0 0

I would submit that a gerrymander by politicians saying fuck the voters and one by voters saying fuck the politicians are two wholly different animals

21 hours ago 10074 2348 47 56

I feel like Sun Tzu really missed out on "Invent Pete Hegseth and give him to the enemy"

1 day ago 3507 570 45 9
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Fractures Emerge Between GOP’s Pro-Pedophilia, Extremely Pro-Pedophilia Wings

1 day ago 19117 4975 280 404

the goal of going to an airport is to leave the airport as swiftly as possible. as douglas adams put it, there is a reason no one has ever invented the phrase "as pretty as an airport."

1 day ago 12 2 1 0

It remains notable that The Onion — The Onion! — has had a stronger moral compass and more clear set of values in this moment than nearly every powerful and well-funded institution in American life.

2 days ago 896 195 10 4

We proved ourselves willing to languish in legislative miasma, and to permit abhorrent misinformation to lessen our own amorality.

2 days ago 4 1 0 0

If MAGA is a plague, then Sandy Hook really was the first slight discoloration, the first cough, the first ghostly ache of inflamed tissue deep within us.

2 days ago 19 2 1 0
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Feeling this on many levels this morning!

2 days ago 1 0 0 0

That’s not my experience, I’ve actually been noticing a marked increase in the amount of BS since the start of the war

2 days ago 216 17 8 0
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homer simpson from the simpsons is sitting in a chair with his mouth open and his hands outstretched . ALT: homer simpson from the simpsons is sitting in a chair with his mouth open and his hands outstretched .
3 days ago 1 0 0 0

A peer reviewed study shows a promising link between flu and shingles vaccines and a reduced risk of dementia. A heroin addict who cut off a raccoon’s penis for “further study” says these vaccines cause autism. For busy Americans, it can be hard to know who to trust.

4 days ago 4672 1178 32 36

It's almost as if everything Trump says about the negotiations bullshit and everyone who believes him is a cultist or a moron.

4 days ago 1684 287 59 5

It’s always “this meeting could’ve been an email” and never “this email could’ve been a fine cask of delectable amontillado wine”

4 days ago 108 32 6 0
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Epigenetic constraints and enhancer innovation link neuronal plasticity to evolutionary adaptation | PNAS How nervous systems balance the generation of robust neuron types with gene expression plasticity mechanisms and how these processes impact cell-ty...

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Epigenetic constraints and enhancer innovation link neuronal plasticity to evolutionary adaptation

www.pnas.org/doi/abs/10.1...

4 days ago 7 2 0 0

Great to see this out. Practical guidance on how to use protein depletion systems in C. elegans

2 weeks ago 23 12 0 0
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maybe she just knows that you're going to let it slide, cause she's a gooooooood dog!

4 days ago 1 0 1 0
Bacteria producing PHB harm C. elegans in multiple ways. Top: Model of how bacterially produced PHB affect C. elegans and which mechanisms can be alleviated by nuc-1 knock out. PHB, poly-β-hydroxybutyrate; Dar, deformed anal region. Bottom: Transmission electron micrograph of bioplastic polyhydroxybutyrate granules filling the intestine of C. elegans. Imaged by Gregor Hendricks, PHD at UMass Chan Medical School Electron Microscopy Core.

Bacteria producing PHB harm C. elegans in multiple ways. Top: Model of how bacterially produced PHB affect C. elegans and which mechanisms can be alleviated by nuc-1 knock out. PHB, poly-β-hydroxybutyrate; Dar, deformed anal region. Bottom: Transmission electron micrograph of bioplastic polyhydroxybutyrate granules filling the intestine of C. elegans. Imaged by Gregor Hendricks, PHD at UMass Chan Medical School Electron Microscopy Core.

Some #bacteria polymerize excess carbon into polyhydroxybutyrate (PHB), a biodegradable storage polymer. This study shows that #PHB -producing bacteria kill #Celegans nematodes by disrupting pharyngeal & intestinal function @plosbiology.org 🧪 plos.io/4cFAwDz

1 week ago 14 6 1 1

Don’t forget the basic research that made it all possible. Ozempuc originally comes from discoveries from Gila monster venom.

Let’s stop the attacks on basic research, and enable the discoveries of the future. SamForNJ.org

1 week ago 436 78 5 4

If you think “That’s ridiculous, a weird elderly guy in robes doing something inappropriate with his hands to a comatose patient while a soldier and anachronistic nurse and crying eagle watches CAN’T be a doctor,” clearly you don’t have an HMO

1 week ago 698 71 12 0
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U.S. Reaches Trade Deal With Pedotopia

1 week ago 1626 258 28 18

Bluesky Says They Like Drinking And Sex. But They Ran Eric Swalwell Out of Office for Drinking and Sex. My Anger At This Hypocrisy Is Exactly Why I Can Only Write For The Atlantic.

1 week ago 1168 85 19 0
Trump Escalates Feud With Unclear Adversary By Posting AI Video Of Self Fucking Basketball

Trump Escalates Feud With Unclear Adversary By Posting AI Video Of Self Fucking Basketball

Trump Escalates Feud With Unclear Adversary By Posting AI Video Of Self Fucking Basketball theonion.com/trump-escalates-feud-wit...

1 week ago 1844 210 35 16
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You think the Pope is weak on crime? You should see what Jesus did for a thief.

1 week ago 1 2 0 0

The idiom "screwed the pooch" should forever be replaced with "fucked the couch"

Example usage: JD Vance and the negotiators really fucked the couch on this one.

1 week ago 344 91 10 7

Okay, sure, but there are five whole continents where Vance didn’t take an L this week.

1 week ago 1757 195 34 15
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If you're one of aides, are you just guzzling Maalox while these interviews happen?

1 week ago 0 0 0 0

I do think the tendency to yeet sex pests out of the democratic tent is an unalloyed good.

1 week ago 606 74 5 2

He knows that those vessels have already priced the bribe into their operating costs

1 week ago 0 0 0 0
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was once New Amsterdam.

1 week ago 10375 1733 103 71