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Posts by Matthew Gibson

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Coventry City: Sky Blues back in the Premier League after a quarter of a century Coventry City are back in the Premier League after 25 years. Here's how they achieved promotion under the guidance of Frank Lampard.

www.bbc.co.uk/sport/footba...

4 days ago 0 0 0 0
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Thanks to @chemguyeli.bsky.social and others for hosting me in St Andrews. We had some great discussions, particularly around ‘impact’/tech transfer (including challenges) and shared some of our experiences. I was also treated to some incredible views over the old course and beach..!

1 week ago 1 0 1 0
ACS Global Outstanding Student and Mentor Awards in Polymer Science and Engineering Sponsored by CME – PMSE

Mentoring the next generation is one of the most rewarding aspects of the job, and I'm delighted to share the 2026 ACS Global Outstanding Student and Mentor Awards in Polymer Science and Engineering with former PhD student Lei Chen!

pmsedivision.org/global-outst...

2 weeks ago 14 1 1 0
Research Associate in Synthetic Inorganic Chemistry:Oxford Road For recent publications relevant to the project see: J. Am. Chem. Soc. 2023, 145, 27993; J. Am. Chem. Soc. 2024, 146, 15000; Nat. Commun. 2019, 10, 3330; Chem. Sci. 2024, 15, 3003.

We are hiring! Two PDRAs in a collaborative project between researchers in the EPSRC National Research Facility for EPR Spectroscopy, Manchester Chemistry, and the Eddleman Quantum Institute. Please share:
www.jobs.manchester.ac.uk/Job/JobDetai...
www.jobs.manchester.ac.uk/Job/JobDetai...

4 weeks ago 4 6 0 0
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Poly(sarcosine)-block-oligo(l-tryptophan) Copolymers as Noncovalent Inhibitors of Protein Aggregation Irreversible protein aggregation can cause loss of function of proteins during storage and transport, presenting a challenge in biotherapeutics, biocatalysis, and the food industry, as well as in basi...

Our latest work @uommib.bsky.social is published @pubs.acs.org . Here we explore new polypeptoids to inhibit protein aggregation in solution, using PEG alternatives.

pubs.acs.org/doi/10.1021/...

1 month ago 0 0 0 0
Research Associate in Life Cycle Assessment of Polymeric Cryoprotectants:Oxford Road As an equal opportunities employer we welcome applicants from all sections of the community regardless of age, sex, gender (or gender identity), ethnicity, disability, sexual orientation and transgender status. All appointments are made on merit.

We have a PRDA vacancy, in collab. with Mike Shaver to explore life cycle analysis of polymeric cryoprotectants, which have many use cases but sustainability metrics are not known.
Experience of LCA essential. Not a ‘wet lab’ project.

www.jobs.manchester.ac.uk/Job/JobDetai...

1 month ago 2 0 0 0
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Polymer-tethered glycosylated gold nanoparticles as versatile tools for bio-sensing Glycans direct many biological recognition and signalling processes, spanning basic cell biology to diagnostics and therapy. Multivalent presentation of glycans is well established to increase avidity...

Our latest work is online @chemcomm.rsc.org @uommib.bsky.social . This feature article covers progress we (+ others) in polymer-tethered glycosylated nanoparticles as tools for glycoscience. This spans synthetic rationale and opportunities for deployment.
pubs.rsc.org/en/content/a...

3 months ago 5 2 0 0
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We've got ISSUES. Literally.

We scraped >100k special issues & over 1 million articles to bring you a PISS-poor paper. We quantify just how many excess papers are published by guest editors abusing special issues to boost their CVs. How bad is it & what can we do?

arxiv.org/abs/2601.07563

A 🧵 1/n

3 months ago 508 315 17 49
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Cryopreservation of Avian Erythrocytes Using Macromolecular Cryoprotectants Erythrocyte (red blood cell) cryopreservation is an essential biotechnology for healthcare (transfusions), diagnostics, conservation, and fundamental research. Mature mammalian erythrocytes are anucleate, do not divide, and cannot undertake protein biosynthesis. In contrast, avian erythrocytes have a distinct evolutionary pathway, retaining their nucleus, and are capable of other limited functions, such as protein biosynthesis, but have a shorter shelf life than mammalian erythrocytes. Here, we report the successful cryopreservation of avian red blood cells using a polyampholyte (macromolecular cryoprotectant), which can reduce intracellular ice formation. Under optimized conditions with 10% DMSO and 60 mg·mL–1 of polyampholyte, ∼90% recovery could be achieved, outperforming a conventional glycerol-based formulation, especially when longer-term storage (up to 6 months) was tested. Scanning electron microscopy confirmed that the cells’ morphology was retained. Confocal fluorescence microscopy showed reduced apoptosis compared to glycerol cryopreservation and confirmed increased recovery of actin (cytoskeleton) polymerization post-thaw. Overall, these results show the potential of macromolecular cryoprotectants to be deployed in nonhuman cryobiology for animal health and potentially species conservation.

Our latest work, showing cryopreservation of Avian red blood cells using our macromolecular cryoprotectants is out now!

pubs.acs.org/doi/full/10....

3 months ago 2 0 0 0
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🎉 Read our latest RSC Applied Polymers blog in which @labgibson.bsky.social and Natalia Gonzalez-Martinez discuss their article ‘Cryopreservation and post-thaw differentiation of monocytes enabled by macromolecular cryoprotectants which restrict intracellular ice formation‘
blogs.rsc.org/lp/202...

4 months ago 1 1 1 0
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Jobs | Job Search | Job Vacancies on jobs.ac.uk Start your UK & international job search for academic jobs, research jobs, science jobs and managerial jobs in leading universities and top...

Would you like to be our Head of Department? A unique opportunity to guide some important developments (see e.g., news.liverpool.ac.uk/2025/11/18/u...). Advert now live on jobs.ac.uk.

www.jobs.ac.uk/job/DPQ019/p...

4 months ago 7 3 0 0
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Blood on demand: New freezing method slashes thaw time for emergency blood transfusions A transformative new method for freezing human red blood cells has been developed by researchers from the Universities of Manchester and Leeds.

A new cryopreservation method using polyampholytes, DMSO, and trehalose significantly reduces thaw time for red blood cells, supporting faster emergency transfusions and improved blood storage. doi.org/g92knc

7 months ago 2 1 0 0
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Scientists develop groundbreaking ‘blood on demand’ technology to revolutionise emergency transfusions Rapid washout: Cocktail-treated RBCs can be washed and prepared for transfusion in just 25 minutes – compared to over 75 minutes for glycerol.Higher recovery rates: The new method results in an averag...

and press release here.
www.manchester.ac.uk/about/news/s...

7 months ago 4 3 0 0
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Towards blood on demand: Rapid post-thaw isolation of red blood cells from multicomponent cryoprotectants Severe blood loss due to trauma, anaemia, or chemotherapy necessitates immediate red blood cell (RBC) transfusions. The short shelf-life of RBCs at 4 …

Our work showing how our macromolecular cryoprotectants unlock "blood on demand' is now published! @uommib.bsky.social From the freezer to fully washed in just 25 minutes, compared to 75 mins using glycerol. Partnership with Tom Whale, Fraser Macrae and more.
www.sciencedirect.com/science/arti....

7 months ago 5 2 1 0

I have so many questions. Why so lilac? Why video shot in the style of Duran Duran’s Wild Boys? Beyond what? But somehow the one that’s bothering me most is why no definite article before “University of Warwick”?

9 months ago 204 26 42 5

Was a fun meeting and nice to catch up with so many colleagues and collaborators.

9 months ago 2 0 0 0
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Label‐Free and Microplate‐Based Dissection of Glycan‐Virus Interactions Using Polymer‐Tethered Glyconanoparticles This work demonstrates the use of polymer-tethered glycosylated gold nanoparticles for the label-free evaluation of influenza virus binding in a simple microplate. Sialylated linear and branched glyc...

Our latest work is out. Glyconanoparticles with complex branched glycans to interrogate influenza binding, with no labels in a microplate. Nice academic/industry collaboration @uommib.bsky.social with Iceni and AZ, and Rob Field. onlinelibrary.wiley.com/doi/10.1002/...

9 months ago 3 2 0 0
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Our team's dedicated microscopy platform for (live) cell imaging is set up @uommib.bsky.social : spinning disk confocal + high-content microscopes, + flow cytometer. This will accelerate our biomaterials discovery for cryo/glyco sciences. Credit to @akalabyabissoyi.bsky.social for hard work!

10 months ago 9 1 0 0

Today I’ll be visiting my Alma Mater, Durham Chemistry, as part of my Corday-Morgan lecture series. I’ll present our latest advances in (macro)molecules for cryobiology.

11 months ago 2 0 0 0
2025 MacroGroup Annual Symposia and Medal Lectures Get ready for two jam-packed days of talks, discussions, and prestigious medal lectures at the 2025 MacroGroup Annual Symposia!

Registration is now open for the Annual MacroGroupUK Symposia and Medal Award Lectures, hosted @uommib.bsky.social 8/9th September. Fabulous line up of speakers. Thanks to sponsors, we have poster prizes and low registration including all refreshments .
www.eventbrite.co.uk/e/2025-macro...

11 months ago 1 2 0 0

This will let us explore the benefits of PVAylation, which is not only ice-binding, water soluble, low toxicity, but is also degradable in the environment

11 months ago 0 0 0 0

This has been a challenge for us, due to lability of the RAFT end-group after deprotection giving us low conversion. Using a photo-reduction, we can cap the reactive end group and install bio-conjugation functionality at the other end.

11 months ago 0 0 1 0
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PVAylation: precision end-functionalized poly(vinyl alcohol) for site-selective bioconjugation The (bio)conjugation of polymers onto proteins enhances their pharmacokinetics and stability, most commonly using PEG (polyethylene glycol), but there is a need for alternatives. Poly(vinyl alcohol), ...

Our latest from Doug is out @chemicalscience.rsc.org @uommib.bsky.social . We introduce #PVAylation: site specific bioconjugation of PVA to proteins, bringing unique ice-binding capability as well as other benefits of polymer-conjugation. pubs.rsc.org/en/content/a...

11 months ago 7 1 1 0
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Biggest commitment to a 3 second joke I've ever seen

1 year ago 90963 28351 885 1334
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We have 3 talks #ACSSpring2025 from the team. Glycodiagnostics, covalent glycocalyx-targeting gene delivery and new poly(oxazoline) materials.

1 year ago 1 0 0 0
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We have another #postdoc vacancy @uommib.bsky.social . Join us to explore new applications of glycan-nanodiagnostics, with our partners Iceni Glycoscience and Field Lab. #glycotime We have world-class facilities in great environment. Pls RT.
www.jobs.manchester.ac.uk/Job/JobDetai...

1 year ago 1 2 0 0

Early morning start, to head over the Pennines to visit Sheffield, hosted by Steve Armes . I’ll be talking Chemical Cryobiology, focussing on new, and unpublished, polymeric protein stabilisation tools. Talk is at 12 noon in chemistry dept.

1 year ago 2 0 0 0
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Our new HPLC from Agilent to go along with our Glyconeer is set up and ready at @uommib.bsky.social . This platform for automated polysaccharide synthesis will transform our capabilities for biomaterial discovery. Science soon!

1 year ago 3 1 0 0
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**SAVE THE DATE** @MacroGroup_UK Annual Meeting and Medals Symposium 8/9th September at Manchester. We look forward to welcoming the polymer community. Details coming soon.

1 year ago 6 4 0 1
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First step of our Glyconeer installation from @glycouniverse.bsky.social complete! Automated synthesis of polysaccharide materials will be coming soon (ish). @uommib.bsky.social

1 year ago 4 0 0 0